Antihypertensive drug therapy in Nepal: findings from May Measurement Months 2019

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisKonferenceabstrakt i tidsskriftForskningpeer review

  • Dinesh Neupane
  • ,
  • Raja Ram Dhungana
  • ,
  • Harikrishna Bhattarai
  • ,
  • Tara Ballav Adhikari
  • Sweta Koirala
  • ,
  • Pratik Khanal
  • ,
  • Shiva Ram Khatiwoda
  • ,
  • Per Kallestrup
  • Bhagawan Koirala
  • ,
  • Kunihiro Matsushita
  • ,
  • Michael Hecht Olsen
  • ,
  • Neil Poulter
  • ,
  • Lawrence J. Appel
Objective: To explore the pattern of antihypertensive medication use among Nepali patients. Design and method: This cross-sectional study in Nepal analysed data from the May Measurement Month 2019 (MMM19). We converted all trade names to generic names and further categorized them according to the class of medication. Participants who provided the information about the name of their antihypertensive medication at the time of the interview were included. Blood pressure (BP) control was defined as a systolic BP < 140 mmHg and diastolic BP < 90. Results: Out of 72,320 who participated in the MMM19, three BP readings were available for 66,955 (93%). Among them, 15,872 (24%) had hypertension and 7,507 (47%) were taking antihypertensive medication. Out of them, 1,434 (19%) provided information about the antihypertensive medication. The mean (SD) of systolic and diastolic blood pressure were 135 mmHg (17 mmHg) and 86 mmHg (11 mmHg). Among those treated for BP, 85%,14% and 1% used 1, 2 and > 2 drugs respectively and 63% were controlled. The proportion of patient taking calcium channel blockers (CCB), angiotensin II receptor blockers (ARBs), and CCB plus ARB were 56%, 24% and 10%, respectively. Amlodipine was the most widely used medicine (55 %) followed by losartan (15%). Blood pressure control rate among participants using telmisartan, losartan plus hydrochlorothiazide, amlodipine plus losartan, losartan and amlodipine were 75%, 68%, 64%, 62% and 62%, respectively. Conclusions: Among individuals taking antihypertensive medications in Nepal, 85% of patients were taking monotherapy, mostly amlodipine. Improvements in BP control will likely require intensification of therapy, potentially through greater use of fixed dose combination therapy.
OriginalsprogEngelsk
TidsskriftJournal of Hypertension
Vol/bind39
Nummere-Supplement 1
Sider (fra-til)e376-e377
Antal sider2
ISSN0263-6352
DOI
StatusUdgivet - apr. 2021

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