Antenatal biological models in the characterization and research of congenital lower urinary tract disorders

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Antenatal biological models in the characterization and research of congenital lower urinary tract disorders. / Cao, Kevin Xi; Milmoe, Nathalie Jane; Cuckow, Peter Malcom; Olsen, Lars Henning; Johal, Navroop Singh; Douglas Winyard, Paul Julian; Long, David Andrew; Fry, Christopher Henry.

I: Journal of Pediatric Urology, Bind 17, Nr. 1, 02.2021, s. 21-29.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisReviewForskningpeer review

Harvard

Cao, KX, Milmoe, NJ, Cuckow, PM, Olsen, LH, Johal, NS, Douglas Winyard, PJ, Long, DA & Fry, CH 2021, 'Antenatal biological models in the characterization and research of congenital lower urinary tract disorders', Journal of Pediatric Urology, bind 17, nr. 1, s. 21-29. https://doi.org/10.1016/j.jpurol.2020.11.022

APA

Cao, K. X., Milmoe, N. J., Cuckow, P. M., Olsen, L. H., Johal, N. S., Douglas Winyard, P. J., Long, D. A., & Fry, C. H. (2021). Antenatal biological models in the characterization and research of congenital lower urinary tract disorders. Journal of Pediatric Urology, 17(1), 21-29. https://doi.org/10.1016/j.jpurol.2020.11.022

CBE

Cao KX, Milmoe NJ, Cuckow PM, Olsen LH, Johal NS, Douglas Winyard PJ, Long DA, Fry CH. 2021. Antenatal biological models in the characterization and research of congenital lower urinary tract disorders. Journal of Pediatric Urology. 17(1):21-29. https://doi.org/10.1016/j.jpurol.2020.11.022

MLA

Vancouver

Cao KX, Milmoe NJ, Cuckow PM, Olsen LH, Johal NS, Douglas Winyard PJ o.a. Antenatal biological models in the characterization and research of congenital lower urinary tract disorders. Journal of Pediatric Urology. 2021 feb;17(1):21-29. https://doi.org/10.1016/j.jpurol.2020.11.022

Author

Cao, Kevin Xi ; Milmoe, Nathalie Jane ; Cuckow, Peter Malcom ; Olsen, Lars Henning ; Johal, Navroop Singh ; Douglas Winyard, Paul Julian ; Long, David Andrew ; Fry, Christopher Henry. / Antenatal biological models in the characterization and research of congenital lower urinary tract disorders. I: Journal of Pediatric Urology. 2021 ; Bind 17, Nr. 1. s. 21-29.

Bibtex

@article{5b4690569b8d41909c7e26441d86ddf1,
title = "Antenatal biological models in the characterization and research of congenital lower urinary tract disorders",
abstract = "Congenital lower urinary tract disorders are a family of diseases affecting both urinary storage and voiding as well as upstream kidney function. Current treatments include surgical reconstruction but many children still fail to achieve urethral continence or progress to chronic kidney disease. New therapies can only be achieved through undertaking research studies to enhance our understanding of congenital lower urinary tract disorders. Animal models form a critical component of this research, a corner of the triangle composed of human in-vitro studies and clinical research. We describe the current animal models for two rare congenital bladder disorders, posterior urethral valves (PUV) and bladder exstrophy (BE). We highlight important areas for researchers to consider when deciding which animal model to use to address particular research questions and outline the strengths and weaknesses of current models available for PUV and BE. Finally, we present ideas for refining animal models for PUV and BE in the future to stimulate future researchers and help them formulate their thinking when working in this field.",
keywords = "Animal models, Bladder exstrophy, Fetal, Posterior urethral valves, Urology",
author = "Cao, {Kevin Xi} and Milmoe, {Nathalie Jane} and Cuckow, {Peter Malcom} and Olsen, {Lars Henning} and Johal, {Navroop Singh} and {Douglas Winyard}, {Paul Julian} and Long, {David Andrew} and Fry, {Christopher Henry}",
note = "Copyright {\textcopyright} 2020. Published by Elsevier Ltd.",
year = "2021",
month = feb,
doi = "10.1016/j.jpurol.2020.11.022",
language = "English",
volume = "17",
pages = "21--29",
journal = "Journal of Pediatric Urology",
issn = "1477-5131",
publisher = "Elsevier BV",
number = "1",

}

RIS

TY - JOUR

T1 - Antenatal biological models in the characterization and research of congenital lower urinary tract disorders

AU - Cao, Kevin Xi

AU - Milmoe, Nathalie Jane

AU - Cuckow, Peter Malcom

AU - Olsen, Lars Henning

AU - Johal, Navroop Singh

AU - Douglas Winyard, Paul Julian

AU - Long, David Andrew

AU - Fry, Christopher Henry

N1 - Copyright © 2020. Published by Elsevier Ltd.

PY - 2021/2

Y1 - 2021/2

N2 - Congenital lower urinary tract disorders are a family of diseases affecting both urinary storage and voiding as well as upstream kidney function. Current treatments include surgical reconstruction but many children still fail to achieve urethral continence or progress to chronic kidney disease. New therapies can only be achieved through undertaking research studies to enhance our understanding of congenital lower urinary tract disorders. Animal models form a critical component of this research, a corner of the triangle composed of human in-vitro studies and clinical research. We describe the current animal models for two rare congenital bladder disorders, posterior urethral valves (PUV) and bladder exstrophy (BE). We highlight important areas for researchers to consider when deciding which animal model to use to address particular research questions and outline the strengths and weaknesses of current models available for PUV and BE. Finally, we present ideas for refining animal models for PUV and BE in the future to stimulate future researchers and help them formulate their thinking when working in this field.

AB - Congenital lower urinary tract disorders are a family of diseases affecting both urinary storage and voiding as well as upstream kidney function. Current treatments include surgical reconstruction but many children still fail to achieve urethral continence or progress to chronic kidney disease. New therapies can only be achieved through undertaking research studies to enhance our understanding of congenital lower urinary tract disorders. Animal models form a critical component of this research, a corner of the triangle composed of human in-vitro studies and clinical research. We describe the current animal models for two rare congenital bladder disorders, posterior urethral valves (PUV) and bladder exstrophy (BE). We highlight important areas for researchers to consider when deciding which animal model to use to address particular research questions and outline the strengths and weaknesses of current models available for PUV and BE. Finally, we present ideas for refining animal models for PUV and BE in the future to stimulate future researchers and help them formulate their thinking when working in this field.

KW - Animal models

KW - Bladder exstrophy

KW - Fetal

KW - Posterior urethral valves

KW - Urology

U2 - 10.1016/j.jpurol.2020.11.022

DO - 10.1016/j.jpurol.2020.11.022

M3 - Review

C2 - 33386226

VL - 17

SP - 21

EP - 29

JO - Journal of Pediatric Urology

JF - Journal of Pediatric Urology

SN - 1477-5131

IS - 1

ER -