Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)

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DOI

  • Troels Thim
  • Matthias Götberg, Skåne University Hospital, Lund
  • ,
  • Ole Fröbert, Department of Cardiology, Örebro University Hospital, Örebro
  • ,
  • Robin Nijveldt, Radboud University Medical Center
  • ,
  • Niels van Royen, Radboud University Medical Center
  • ,
  • Sergio Bravo Baptista, Associação Protectora dos Diabéticos de Portugal (APDP), Lisbon, Portugal.
  • ,
  • Sasha Koul, Skåne University Hospital, Lund
  • ,
  • Thomas Kellerth, Department of Cardiology, Örebro University Hospital, Örebro
  • ,
  • Hans Erik Bøtker
  • Christian Juhl Terkelsen
  • Evald Høj Christiansen
  • Lars Jakobsen, Aarhus Universitet
  • ,
  • Steen Dalby Kristensen
  • Michael Maeng

OBJECTIVE: To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI).

RESULTS: We measured iFR and FFR at staged follow-up in 112 STEMI patients with 146 nonculprit stenoses. Median interval between STEMI and follow-up was 16 (interquartile range 5-32) days. Agreement between iFR and FFR was 77% < 5 days after STEMI and 86% after ≥ 5 days (p = 0.19). Among cases with disagreement, the proportion of cases with hemodynamically significant iFR and non-significant FFR were different when assessed < 5 days (5 in 8, 63%) versus ≥ 5 days (3 in 15, 20%) after STEMI (p = 0.04). Overall classification agreement between iFR and FFR was comparable to that observed in stable patients. Time interval between STEMI and follow-up evaluation may impact agreement between iFR and FFR.

OriginalsprogEngelsk
Artikelnummer410
TidsskriftBMC Research Notes
Vol/bind13
Nummer1
Antal sider3
ISSN1756-0500
DOI
StatusUdgivet - 2020

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