Advances in PET Imaging of Large Vessel Vasculitis: An Update and Future Trends

Kornelis S.M. van der Geest, Olivier Gheysens, Lars C. Gormsen, Andor W.J.M. Glaudemans, Charalampos Tsoumpas, Elisabeth Brouwer, Pieter H. Nienhuis, Gijs D. van Praagh, Riemer H.J.A. Slart*

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisReviewForskningpeer review

Abstract

Systemic vasculitides are autoimmune diseases characterized by inflammation of blood vessels. They are categorized based on the size of the preferentially affected blood vessels: large-, medium-, and small-vessel vasculitides. The main forms of large-vessel vasculitis include giant cell arteritis (GCA) and Takayasu arteritis (TAK). Depending on the location of the affected vessels, various imaging modalities can be employed for diagnosis of large vessel vasculitis: ultrasonography (US), magnetic resonance angiography (MRA), computed tomography angiography (CTA), and [18F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT). These imaging tools offer complementary information about vascular changes occurring in vasculitis. Recent advances in PET imaging in large vessel vasculitis include the introduction of digital long axial field-of-view PET/CT, dedicated acquisition, quantitative methodologies, and the availability of novel radiopharmaceuticals. This review aims to provide an update on the current status of PET imaging in large vessel vasculitis and to share the latest developments on imaging vasculitides.

OriginalsprogEngelsk
TidsskriftSeminars in Nuclear Medicine
Vol/bind54
Nummer5
Sider (fra-til)753-760
Antal sider8
ISSN0001-2998
DOI
StatusUdgivet - sep. 2024

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