TY - JOUR
T1 - Advances in PET Imaging of Large Vessel Vasculitis
T2 - An Update and Future Trends
AU - van der Geest, Kornelis S.M.
AU - Gheysens, Olivier
AU - Gormsen, Lars C.
AU - Glaudemans, Andor W.J.M.
AU - Tsoumpas, Charalampos
AU - Brouwer, Elisabeth
AU - Nienhuis, Pieter H.
AU - van Praagh, Gijs D.
AU - Slart, Riemer H.J.A.
PY - 2024/9
Y1 - 2024/9
N2 - Systemic vasculitides are autoimmune diseases characterized by inflammation of blood vessels. They are categorized based on the size of the preferentially affected blood vessels: large-, medium-, and small-vessel vasculitides. The main forms of large-vessel vasculitis include giant cell arteritis (GCA) and Takayasu arteritis (TAK). Depending on the location of the affected vessels, various imaging modalities can be employed for diagnosis of large vessel vasculitis: ultrasonography (US), magnetic resonance angiography (MRA), computed tomography angiography (CTA), and [18F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT). These imaging tools offer complementary information about vascular changes occurring in vasculitis. Recent advances in PET imaging in large vessel vasculitis include the introduction of digital long axial field-of-view PET/CT, dedicated acquisition, quantitative methodologies, and the availability of novel radiopharmaceuticals. This review aims to provide an update on the current status of PET imaging in large vessel vasculitis and to share the latest developments on imaging vasculitides.
AB - Systemic vasculitides are autoimmune diseases characterized by inflammation of blood vessels. They are categorized based on the size of the preferentially affected blood vessels: large-, medium-, and small-vessel vasculitides. The main forms of large-vessel vasculitis include giant cell arteritis (GCA) and Takayasu arteritis (TAK). Depending on the location of the affected vessels, various imaging modalities can be employed for diagnosis of large vessel vasculitis: ultrasonography (US), magnetic resonance angiography (MRA), computed tomography angiography (CTA), and [18F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT). These imaging tools offer complementary information about vascular changes occurring in vasculitis. Recent advances in PET imaging in large vessel vasculitis include the introduction of digital long axial field-of-view PET/CT, dedicated acquisition, quantitative methodologies, and the availability of novel radiopharmaceuticals. This review aims to provide an update on the current status of PET imaging in large vessel vasculitis and to share the latest developments on imaging vasculitides.
UR - http://www.scopus.com/inward/record.url?scp=85188993574&partnerID=8YFLogxK
U2 - 10.1053/j.semnuclmed.2024.03.001
DO - 10.1053/j.semnuclmed.2024.03.001
M3 - Review
C2 - 38538456
AN - SCOPUS:85188993574
SN - 0001-2998
VL - 54
SP - 753
EP - 760
JO - Seminars in Nuclear Medicine
JF - Seminars in Nuclear Medicine
IS - 5
ER -