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Advanced Pharmaco-EEG Reveals Morphine Induced Changes in the Brain's Pain Network
Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review
- Dina Lelic
- Anne Estrup Olesen, Danmark
- Christina Brock
- Camilla Staahl, Danmark
- Asbjørn Mohr Drewes
- Medicinsk Gastroenterologisk Afdeling, Medicinsk Center, Aalborg Sygehus
- Institut for Klinisk Medicin - Medicinsk Gastroenterologisk afdeling, AAL
- Institut for Klinisk Medicin - Center for visceral biomekanik og smerte, AAL
: By using a novel brain source modeling approach, where the evoked potential (EP) signal was decomposed with multichannel matching pursuit (MMP) before source localization, we investigated brain generators of EPs after a pain stimulus in the esophagus before and after administration of placebo/morphine. We showed that this new approach of pharmaco-electroencephalogram (EEG) analysis can shed light on subtle changes, which cannot be foreseen from conventional analysis (amplitude/latency/topography).
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Journal of Clinical Neurophysiology |
| Vol/bind | 29 |
| Nummer | 3 |
| Sider (fra-til) | 219-25 |
| Antal sider | 7 |
| ISSN | 0736-0258 |
| DOI | |
| Status | Udgivet - 2012 |
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