Adult post-cardiac arrest interventions: An overview of randomized clinical trials

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Adult post-cardiac arrest interventions : An overview of randomized clinical trials. / Andersen, Lars W; Carøe Lind, Peter; Vammen, Lauge et al.

I: Resuscitation, Bind 147, 02.2020, s. 1-11.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

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@article{76aa3e66ae4d49c3ae615f97bd574cbe,
title = "Adult post-cardiac arrest interventions: An overview of randomized clinical trials",
abstract = "AIM: To provide an overview of published and registered trials related to post-cardiac arrest interventions.DATA SOURCE: We searched PubMed and the International Clinical Trials Registry Platform for randomized clinical trials in adults specifically addressing a post-cardiac arrest intervention.RESULTS: We identified 65 manuscripts reporting randomized clinical trials. The majority of the trials were published within the last 10 years and the sample sizes were generally low with a median of 90 participants (quartiles: 49, 262; range: 9, 1359). The majority of the trials were conducted in out-of-hospital cardiac arrest (79%), while only 6% were conducted specifically in in-hospital cardiac arrest and 15% included both in- and out-of-hospital cardiac arrest. We identified 48 registered trials online. The median target sample size is 100 participants (quartiles: 60, 400; range: 20, 1900). The majority of trials are enrolling patients with out-of-hospital cardiac arrest (71%) while 6% specifically focuses on in-hospital cardiac arrest.CONCLUSION: This review provides an overview of published and registered trials addressing post-cardiac arrest interventions. We believe this information will be relevant to guide future research.",
author = "Andersen, {Lars W} and {Car{\o}e Lind}, Peter and Lauge Vammen and Maria H{\o}ybye and Holmberg, {Mathias J} and Asger Granfeldt",
note = "Copyright {\textcopyright} 2019. Published by Elsevier B.V.",
year = "2020",
month = feb,
doi = "10.1016/j.resuscitation.2019.12.003",
language = "English",
volume = "147",
pages = "1--11",
journal = "Resuscitation",
issn = "0300-9572",
publisher = "Elsevier Ireland Ltd.",

}

RIS

TY - JOUR

T1 - Adult post-cardiac arrest interventions

T2 - An overview of randomized clinical trials

AU - Andersen, Lars W

AU - Carøe Lind, Peter

AU - Vammen, Lauge

AU - Høybye, Maria

AU - Holmberg, Mathias J

AU - Granfeldt, Asger

N1 - Copyright © 2019. Published by Elsevier B.V.

PY - 2020/2

Y1 - 2020/2

N2 - AIM: To provide an overview of published and registered trials related to post-cardiac arrest interventions.DATA SOURCE: We searched PubMed and the International Clinical Trials Registry Platform for randomized clinical trials in adults specifically addressing a post-cardiac arrest intervention.RESULTS: We identified 65 manuscripts reporting randomized clinical trials. The majority of the trials were published within the last 10 years and the sample sizes were generally low with a median of 90 participants (quartiles: 49, 262; range: 9, 1359). The majority of the trials were conducted in out-of-hospital cardiac arrest (79%), while only 6% were conducted specifically in in-hospital cardiac arrest and 15% included both in- and out-of-hospital cardiac arrest. We identified 48 registered trials online. The median target sample size is 100 participants (quartiles: 60, 400; range: 20, 1900). The majority of trials are enrolling patients with out-of-hospital cardiac arrest (71%) while 6% specifically focuses on in-hospital cardiac arrest.CONCLUSION: This review provides an overview of published and registered trials addressing post-cardiac arrest interventions. We believe this information will be relevant to guide future research.

AB - AIM: To provide an overview of published and registered trials related to post-cardiac arrest interventions.DATA SOURCE: We searched PubMed and the International Clinical Trials Registry Platform for randomized clinical trials in adults specifically addressing a post-cardiac arrest intervention.RESULTS: We identified 65 manuscripts reporting randomized clinical trials. The majority of the trials were published within the last 10 years and the sample sizes were generally low with a median of 90 participants (quartiles: 49, 262; range: 9, 1359). The majority of the trials were conducted in out-of-hospital cardiac arrest (79%), while only 6% were conducted specifically in in-hospital cardiac arrest and 15% included both in- and out-of-hospital cardiac arrest. We identified 48 registered trials online. The median target sample size is 100 participants (quartiles: 60, 400; range: 20, 1900). The majority of trials are enrolling patients with out-of-hospital cardiac arrest (71%) while 6% specifically focuses on in-hospital cardiac arrest.CONCLUSION: This review provides an overview of published and registered trials addressing post-cardiac arrest interventions. We believe this information will be relevant to guide future research.

U2 - 10.1016/j.resuscitation.2019.12.003

DO - 10.1016/j.resuscitation.2019.12.003

M3 - Journal article

C2 - 31846693

VL - 147

SP - 1

EP - 11

JO - Resuscitation

JF - Resuscitation

SN - 0300-9572

ER -