Abstract
We evaluated the accuracy of biology informed genomic prediction for dry matter intake in 2,162 Dutch Holstein cows. Sequence variants were selected from meta-analyses including GWAS summary statistics for QTL and metabolomic QTL in several dairy and crossbred beef populations. Selected variants were prioritized in GBLUP models in a five-fold crossvalidation. The accuracies were compared to genomic prediction based on routine 50k genotype data. The average accuracy for the 50k scenario was 0.683. Adding selected sequence variants in the GBLUP model did not improve the accuracies for dry matter intake. Next steps will
include testing Bayesian variable selection methods to prioritize variants in genomic prediction for dry matter intake.
include testing Bayesian variable selection methods to prioritize variants in genomic prediction for dry matter intake.
Originalsprog | Engelsk |
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Titel | WCGALP 2022 Programme book |
Antal sider | 4 |
Forlag | Wageningen Academic Publishers |
Publikationsdato | jul. 2022 |
Status | Udgivet - jul. 2022 |
Begivenhed | World Congress on Genetics Applied to Livestock Production - Rotterdam, Holland Varighed: 3 jul. 2022 → 8 jul. 2022 Konferencens nummer: 12 https://wcgalp.com/ |
Konference
Konference | World Congress on Genetics Applied to Livestock Production |
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Nummer | 12 |
Land/Område | Holland |
By | Rotterdam |
Periode | 03/07/2022 → 08/07/2022 |
Internetadresse |