A single-domain antibody targeting complement component c5 acts as a selective inhibitor of the terminal pathway of the complement system and thus functionally mimicks the c-terminal domain of the staphylococcus aureusSSL7 protein

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A single-domain antibody targeting complement component c5 acts as a selective inhibitor of the terminal pathway of the complement system and thus functionally mimicks the c-terminal domain of the staphylococcus aureusSSL7 protein. / Yatime, Laure; Merle, Nicolas S.; Hansen, Annette G.; Friis, Niels Anton; Østergaard, Jakob A.; Bjerre, Mette; Roumenina, Lubka T.; Thiel, Steffen; Kristensen, Peter; Andersen, Gregers R.

I: Frontiers in Immunology, Bind 9, 2822, 29.11.2018.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

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@article{ed20d8a05410466da2d3f78a6cbb3082,
title = "A single-domain antibody targeting complement component c5 acts as a selective inhibitor of the terminal pathway of the complement system and thus functionally mimicks the c-terminal domain of the staphylococcus aureusSSL7 protein",
keywords = "Bacteriolysis, Complement, Hemolysis, Paroxysmal nocturnal hemoglobinuria, Pathogen mimicry, Single-domain antibody, Terminal pathway inhibition",
author = "Laure Yatime and Merle, {Nicolas S.} and Hansen, {Annette G.} and Friis, {Niels Anton} and {\O}stergaard, {Jakob A.} and Mette Bjerre and Roumenina, {Lubka T.} and Steffen Thiel and Peter Kristensen and Andersen, {Gregers R.}",
year = "2018",
month = "11",
day = "29",
doi = "10.3389/fimmu.2018.02822",
language = "English",
volume = "9",
journal = "Frontiers in Immunology",
issn = "1664-3224",
publisher = "Frontiers Research Foundation",

}

RIS

TY - JOUR

T1 - A single-domain antibody targeting complement component c5 acts as a selective inhibitor of the terminal pathway of the complement system and thus functionally mimicks the c-terminal domain of the staphylococcus aureusSSL7 protein

AU - Yatime, Laure

AU - Merle, Nicolas S.

AU - Hansen, Annette G.

AU - Friis, Niels Anton

AU - Østergaard, Jakob A.

AU - Bjerre, Mette

AU - Roumenina, Lubka T.

AU - Thiel, Steffen

AU - Kristensen, Peter

AU - Andersen, Gregers R.

PY - 2018/11/29

Y1 - 2018/11/29

KW - Bacteriolysis

KW - Complement

KW - Hemolysis

KW - Paroxysmal nocturnal hemoglobinuria

KW - Pathogen mimicry

KW - Single-domain antibody

KW - Terminal pathway inhibition

UR - http://www.scopus.com/inward/record.url?scp=85057611268&partnerID=8YFLogxK

U2 - 10.3389/fimmu.2018.02822

DO - 10.3389/fimmu.2018.02822

M3 - Journal article

VL - 9

JO - Frontiers in Immunology

JF - Frontiers in Immunology

SN - 1664-3224

M1 - 2822

ER -