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A prospective study of influenza vaccination and time to pregnancy

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A prospective study of influenza vaccination and time to pregnancy. / Orta, Olivia R.; Hatch, Elizabeth E.; Regan, Annette K.; Perkins, Rebecca; Wesselink, Amelia K.; Willis, Sydney K.; Mikkelsen, Ellen M.; Rothman, Kenneth J.; Wise, Lauren A.

I: Vaccine, Bind 38, Nr. 27, 06.2020, s. 4246-4251.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Orta, OR, Hatch, EE, Regan, AK, Perkins, R, Wesselink, AK, Willis, SK, Mikkelsen, EM, Rothman, KJ & Wise, LA 2020, 'A prospective study of influenza vaccination and time to pregnancy', Vaccine, bind 38, nr. 27, s. 4246-4251. https://doi.org/10.1016/j.vaccine.2020.04.054

APA

Orta, O. R., Hatch, E. E., Regan, A. K., Perkins, R., Wesselink, A. K., Willis, S. K., Mikkelsen, E. M., Rothman, K. J., & Wise, L. A. (2020). A prospective study of influenza vaccination and time to pregnancy. Vaccine, 38(27), 4246-4251. https://doi.org/10.1016/j.vaccine.2020.04.054

CBE

Orta OR, Hatch EE, Regan AK, Perkins R, Wesselink AK, Willis SK, Mikkelsen EM, Rothman KJ, Wise LA. 2020. A prospective study of influenza vaccination and time to pregnancy. Vaccine. 38(27):4246-4251. https://doi.org/10.1016/j.vaccine.2020.04.054

MLA

Vancouver

Orta OR, Hatch EE, Regan AK, Perkins R, Wesselink AK, Willis SK o.a. A prospective study of influenza vaccination and time to pregnancy. Vaccine. 2020 jun;38(27):4246-4251. https://doi.org/10.1016/j.vaccine.2020.04.054

Author

Orta, Olivia R. ; Hatch, Elizabeth E. ; Regan, Annette K. ; Perkins, Rebecca ; Wesselink, Amelia K. ; Willis, Sydney K. ; Mikkelsen, Ellen M. ; Rothman, Kenneth J. ; Wise, Lauren A. / A prospective study of influenza vaccination and time to pregnancy. I: Vaccine. 2020 ; Bind 38, Nr. 27. s. 4246-4251.

Bibtex

@article{25e08930c0dc4ed39d88f4cb663330a3,
title = "A prospective study of influenza vaccination and time to pregnancy",
abstract = "Background: Although pregnancy planners are a priority group for influenza vaccination in the United States, little is known about the extent to which influenza vaccination affects fecundability. Methods: We analyzed data from Pregnancy Study Online (PRESTO), an ongoing preconception cohort study of North American pregnancy planners. During June 2013 to August 2019, 8654 female participants and 2137 of their male partners completed a baseline questionnaire and were followed until reported pregnancy, fertility treatment initiation, loss to follow-up, or 12 menstrual cycles of attempt time, whichever came first. At baseline, male and female participants reported whether they received an influenza vaccination in the past year and the date of vaccination. We used proportional probabilities regression models to estimate fecundability ratios (FR) and 95% confidence intervals (CI) comparing those who did and did not report influenza vaccination, adjusting for demographics, anthropometrics, behavioral factors, and medical history. Results: Influenza vaccination in the past year was more common among female participants than male participants (47% vs. 37%). FRs were 1.04 (95% CI: 0.98–1.10) for female vaccination and 1.03 (95% CI: 0.93–1.14) for male vaccination. Among the 2137 couples with complete data on both partners, for 40% neither partner was vaccinated, 23% had female-only vaccination, 9% had male-only vaccination, and in 28% both partners were vaccinated. Compared with couples in which neither participant was vaccinated, FRs were 1.13 for female-only vaccination (95% CI: 0.99–1.29), 0.94 for male-only vaccination (95% CI: 0.78–1.12), and 1.07 when both partners were vaccinated (95% CI: 0.94–1.21). When restricted to recent vaccination before peak influenza season, results were similar. Conclusions: Our data indicate no adverse effect of influenza vaccination on fecundability.",
keywords = "Conception, Couples, Fertility, Flu, Influenza, Pregnancy",
author = "Orta, {Olivia R.} and Hatch, {Elizabeth E.} and Regan, {Annette K.} and Rebecca Perkins and Wesselink, {Amelia K.} and Willis, {Sydney K.} and Mikkelsen, {Ellen M.} and Rothman, {Kenneth J.} and Wise, {Lauren A.}",
year = "2020",
month = jun,
doi = "10.1016/j.vaccine.2020.04.054",
language = "English",
volume = "38",
pages = "4246--4251",
journal = "Vaccine",
issn = "0264-410X",
publisher = "Elsevier Ltd",
number = "27",

}

RIS

TY - JOUR

T1 - A prospective study of influenza vaccination and time to pregnancy

AU - Orta, Olivia R.

AU - Hatch, Elizabeth E.

AU - Regan, Annette K.

AU - Perkins, Rebecca

AU - Wesselink, Amelia K.

AU - Willis, Sydney K.

AU - Mikkelsen, Ellen M.

AU - Rothman, Kenneth J.

AU - Wise, Lauren A.

PY - 2020/6

Y1 - 2020/6

N2 - Background: Although pregnancy planners are a priority group for influenza vaccination in the United States, little is known about the extent to which influenza vaccination affects fecundability. Methods: We analyzed data from Pregnancy Study Online (PRESTO), an ongoing preconception cohort study of North American pregnancy planners. During June 2013 to August 2019, 8654 female participants and 2137 of their male partners completed a baseline questionnaire and were followed until reported pregnancy, fertility treatment initiation, loss to follow-up, or 12 menstrual cycles of attempt time, whichever came first. At baseline, male and female participants reported whether they received an influenza vaccination in the past year and the date of vaccination. We used proportional probabilities regression models to estimate fecundability ratios (FR) and 95% confidence intervals (CI) comparing those who did and did not report influenza vaccination, adjusting for demographics, anthropometrics, behavioral factors, and medical history. Results: Influenza vaccination in the past year was more common among female participants than male participants (47% vs. 37%). FRs were 1.04 (95% CI: 0.98–1.10) for female vaccination and 1.03 (95% CI: 0.93–1.14) for male vaccination. Among the 2137 couples with complete data on both partners, for 40% neither partner was vaccinated, 23% had female-only vaccination, 9% had male-only vaccination, and in 28% both partners were vaccinated. Compared with couples in which neither participant was vaccinated, FRs were 1.13 for female-only vaccination (95% CI: 0.99–1.29), 0.94 for male-only vaccination (95% CI: 0.78–1.12), and 1.07 when both partners were vaccinated (95% CI: 0.94–1.21). When restricted to recent vaccination before peak influenza season, results were similar. Conclusions: Our data indicate no adverse effect of influenza vaccination on fecundability.

AB - Background: Although pregnancy planners are a priority group for influenza vaccination in the United States, little is known about the extent to which influenza vaccination affects fecundability. Methods: We analyzed data from Pregnancy Study Online (PRESTO), an ongoing preconception cohort study of North American pregnancy planners. During June 2013 to August 2019, 8654 female participants and 2137 of their male partners completed a baseline questionnaire and were followed until reported pregnancy, fertility treatment initiation, loss to follow-up, or 12 menstrual cycles of attempt time, whichever came first. At baseline, male and female participants reported whether they received an influenza vaccination in the past year and the date of vaccination. We used proportional probabilities regression models to estimate fecundability ratios (FR) and 95% confidence intervals (CI) comparing those who did and did not report influenza vaccination, adjusting for demographics, anthropometrics, behavioral factors, and medical history. Results: Influenza vaccination in the past year was more common among female participants than male participants (47% vs. 37%). FRs were 1.04 (95% CI: 0.98–1.10) for female vaccination and 1.03 (95% CI: 0.93–1.14) for male vaccination. Among the 2137 couples with complete data on both partners, for 40% neither partner was vaccinated, 23% had female-only vaccination, 9% had male-only vaccination, and in 28% both partners were vaccinated. Compared with couples in which neither participant was vaccinated, FRs were 1.13 for female-only vaccination (95% CI: 0.99–1.29), 0.94 for male-only vaccination (95% CI: 0.78–1.12), and 1.07 when both partners were vaccinated (95% CI: 0.94–1.21). When restricted to recent vaccination before peak influenza season, results were similar. Conclusions: Our data indicate no adverse effect of influenza vaccination on fecundability.

KW - Conception

KW - Couples

KW - Fertility

KW - Flu

KW - Influenza

KW - Pregnancy

UR - http://www.scopus.com/inward/record.url?scp=85084435373&partnerID=8YFLogxK

U2 - 10.1016/j.vaccine.2020.04.054

DO - 10.1016/j.vaccine.2020.04.054

M3 - Journal article

C2 - 32409134

AN - SCOPUS:85084435373

VL - 38

SP - 4246

EP - 4251

JO - Vaccine

JF - Vaccine

SN - 0264-410X

IS - 27

ER -