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A Bovine PeptideAtlas of milk and mammary gland proteomes

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  • Stine Lønnerup Bislev, Danmark
  • Eric W Deutsch, Institute for Systems Biology, Seattle, USA
  • Zhi Sun, Institute for Systems Biology, Seattle, USA
  • Terry Farrah, Institute for Systems Biology, Seattle, USA
  • Ruedi Aebersold, Institute of Molecular Systems Biology, ETH Zurich, Schweiz
  • Robert L Moritz, Institute for Systems Biology, Seattle, USA
  • Emøke Bendixen
  • Marius Cosmin Codrea, Danmark
Proteome information resources of farm animals are lagging behind those of the classical model organisms despite their important biological and economic relevance. Here, we present a Bovine PeptideAtlas, representing a first collection of Bos taurus proteome data sets within the PeptideAtlas framework. This database was built primarily as a source of information for designing selected reaction monitoring assays for studying milk production and mammary gland health, but it has an intrinsic general value for the farm animal research community. The Bovine PeptideAtlas comprises 1921 proteins at 1.2% false discovery rate (FDR) and 8559 distinct peptides at 0.29% FDR identified in 107 samples from six tissues. The PeptideAtlas web interface has a rich set of visualization and data exploration tools, enabling users to interactively mine information about individual proteins and peptides, their prototypic features, genome mappings, and supporting spectral evidence.
OriginalsprogEngelsk
TidsskriftProteomics
Vol/bind12
Nummer18
Sider (fra-til)2895-2899
Antal sider5
ISSN1615-9853
DOI
StatusUdgivet - sep. 2012

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