Preventing Infection in the Gut of developing Piglets - and thus Antimicrobial Resistance - by disentAngling the interface of DIet, the host and the Gastrointestinal Microbiome’

The vision of PIG-PARADIGM is to reduce the overall need for antimicrobial treatments and mitigate the spread
of AMR by delivering fundamental knowledge on what defines healthy and robust intestinal function in pigs; on
what determines the host and microbial mechanisms leading to post weaning diarrhea (PWD) and subsequent
antibiotic use; and how microbiome and nutrition can be modulated to prevent the need for antibiotic use by
promoting resilience to early life stress and intestinal infections.

PIG-PARADIGM aims to establish an
urgently needed fundamental knowledge base of the pig intestinal microbiome and mechanisms underlying its
interplay with the growing pig and the diet.