Metabolic changes by carbohydrate and protein quality in the development and mitigation of metabolic syndrome

Project aim and background
There is an alarming rise in the frequency of metabolic syndrome (MeS), which increases the risk of cardiovascular disease (CVD) two-fold and type 2 diabetes (T2D) five-fold. Easy access to energy dense, unhealthy foods is a key factor responsible for this development. In this project we will study dietary strategies based on high protein and dietary fibre (DF) to mitigate MeS and the risk for CVD in human subjects fulfilling the criteria for MeS.
Project description
To obtain a more in-depth knowledge we will use an obese
porcine model, which allow more invasive exploration than in humans. In this model we will study the molecular consequences in adipose tissue and biofluids of development of obesity.