Torben Sigsgaard

Cleaning at Home and at Work in Relation to Lung Function Decline and Airway Obstruction

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

DOI

  • Øistein Svanes, 2 Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway., Norge
  • Randi J Bertelsen, Norge
  • Stein H L Lygre, 2 Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway., Norge
  • Anne E Carsin, 5 Centro de Investigación Biomédica en Red Epidemiología y Salud Pública, Barcelona, Spain., Spanien
  • Josep M Antó, Spanien
  • Bertil Forsberg, 6 Division of Occupational and Environmental Medicine, Umeå University, Umeå, Sweden., Sverige
  • José M García-García, 7 Pneumology Department, University Hospital San Agustín, Avilés, Spain., Spanien
  • José A Gullón, 7 Pneumology Department, University Hospital San Agustín, Avilés, Spain., Spanien
  • Joachim Heinrich, 8 Institute and Outpatient Clinic for Occupational and Environmental Medicine, Clinic Center, Ludwig Maximillian University, Comprehensive Pneumology Centre Munich, German Centre for Lung Research, Muenchen, Germany., Tyskland
  • Mathias Holm, 9 Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden., Sverige
  • Manolis Kogevinas, Spanien
  • Isabel Urrutia, 10 Pulmonology Department, Galdakao Hospital, Galdakao, Spain., Spanien
  • Bénédicte Leynaert, 12 Unité mixte de recherche 1152, Université Paris Diderot Paris7, Paris, France., Frankrig
  • Jesús M Moratalla, 13 Servicio de Numología, Complejo Hospitalario Universitario de Albacete, Albacete, Spain., Spanien
  • Nicole Le Moual, 15 Université Versailles St-Quentin-en-Yvelines, Unité mixte de recherche-S 1168, Yvelines, France., Frankrig
  • Theodore Lytras, 16 Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain., Spanien
  • Dan Norbäck, 17 Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden., Sverige
  • Dennis Nowak, 8 Institute and Outpatient Clinic for Occupational and Environmental Medicine, Clinic Center, Ludwig Maximillian University, Comprehensive Pneumology Centre Munich, German Centre for Lung Research, Muenchen, Germany., Tyskland
  • Mario Olivieri, 18 University Hospital of Verona, Verona, Italy., Italien
  • Isabelle Pin, 19 Pneumologie Pédiatrique, Antenne Pédiatrique du Centres d'Investigation Clinique Grenoble, France., Frankrig
  • Nicole Probst-Hensch, 21 Department Public Health, University of Basel, Basel, Switzerland., Schweiz
  • Vivi Schlünssen
  • Torben Sigsgaard
  • Trude D Skorge, 2 Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway., Norge
  • Simona Villani, 24 Unit of Biostatistics and Clinical Epidemiology, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy; and., Italien
  • Debbie Jarvis, 25 National Heart and Lung Institute, Imperial College, London, United Kingdom., Storbritannien
  • Jan P Zock, Spanien
  • Cecilie Svanes, 2 Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway., Norge

RATIONALE: Cleaning tasks may imply exposure to chemical agents with potential harmful effects to the respiratory system, and increased risk of asthma and respiratory symptoms among professional cleaners and in persons cleaning at home has been reported. Long-term consequences of cleaning agents on respiratory health are, however, not well described.

OBJECTIVES: This study aimed to investigate long-term effects of occupational cleaning and cleaning at home on lung function decline and airway obstruction.

METHODS: The European Community Respiratory Health Survey (ECRHS) investigated a multicenter population-based cohort at three time points over 20 years. A total of 6,235 participants with at least one lung function measurement from 22 study centers, who in ECRHS II responded to questionnaire modules concerning cleaning activities between ECRHS I and ECRHS II, were included. The data were analyzed with mixed linear models adjusting for potential confounders.

MEASUREMENTS AND MAIN RESULTS: As compared with women not engaged in cleaning (ΔFEV1 = -18.5 ml/yr), FEV1 declined more rapidly in women responsible for cleaning at home (-22.1; P = 0.01) and occupational cleaners (-22.4; P = 0.03). The same was found for decline in FVC (ΔFVC = -8.8 ml/yr; -13.1, P = 0.02; and -15.9, P = 0.002; respectively). Both cleaning sprays and other cleaning agents were associated with accelerated FEV1 decline (-22.0, P = 0.04; and -22.9, P = 0.004; respectively). Cleaning was not significantly associated with lung function decline in men or with FEV1/FVC decline or airway obstruction.

CONCLUSIONS: Women cleaning at home or working as occupational cleaners had accelerated decline in lung function, suggesting that exposures related to cleaning activities may constitute a risk to long-term respiratory health.

OriginalsprogEngelsk
TidsskriftAmerican Journal of Respiratory and Critical Care Medicine
Vol/bind197
Nummer9
Sider (fra-til)1157-1163
Antal sider7
ISSN1073-449X
DOI
StatusUdgivet - 1 maj 2018

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