Torben Sigsgaard

Agreement of offspring-reported parental smoking status: the RHINESSA generation study

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

DOI

  • Kathrine Pape
  • Cecilie Svanes, 29 Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway., Norge
  • Andrei Malinovschi, Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden., Sverige
  • Bryndis Benediktsdottir, University of Iceland, Medical Faculty, Iceland. Primary Health Care Center, Gardabaer, Iceland., Island
  • Caroline Lodge, Centre for Molecular, Environmental, Genetic & Analytic (MEGA) Epidemiology, University of Melbourne, Melbourne, Australia., Australien
  • Christer Janson, Department of Medical Sciences, Respiratory-, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden., Sverige
  • Jesus Moratalla, Department of Internal Medicine, Albacete University Hospital, Albacete, Spain., Spanien
  • José Luis Sánchez-Ramos, Department of Nursing, University of Huelva, Huelva, Spain., Spanien
  • Lennart Bråbäck, Department of Public Health and Clinical Medicine/Occupational & Environmental Medicine, Umeå University, Umeå, Sweden., Sverige
  • Mathias Holm, Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden; Section of Occupational and Environmental Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Sverige
  • Rain Jögi, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Division of Experimental Asthma Research, University of Kiel, Kiel, Germany., Estland
  • Randi Jacobsen Bertelsen, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway., Norge
  • Torben Sigsgaard
  • Ane Johannessen, 29 Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway., Norge
  • Vivi Schlünssen

BACKGROUND: With increasing interest in exposure effects across generations, it is crucial to assess the validity of information given on behalf of others.

AIMS: To compare adult's report of their parent's smoking status against parent's own report and examine predictors for discrepant answers.

METHODS: We studied 7185 offspring (18-51 years) and one of their parents, n = 5307 (27-67 years) participating in the Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) generation study. Information about parent's smoking status during offspring's childhood and mother's smoking status during pregnancy was obtained by questionnaires from parents and their offspring. We calculated sensitivity, specificity and Cohen's Kappa [κ] for agreement using parent's own report as the gold standard. We performed logistic regression to examine if offspring's sex, age, educational level, asthma status, own smoking status or parental status, as well as the parent's sex and amount of smoking during childhood predicted disagreement.

RESULTS: The sensitivity for offspring's correct report of parent's smoking status during childhood (0-10 years) was 0.82 (95% CI 0.81-0.84), specificity was 0.95 (95% CI 0.95-0.96) and a good agreement was observed, κ = 0.79 (95% CI 0.78-0.80). Offspring's report of mothers' smoking status during pregnancy showed a lower sensitivity, 0.66 (95% CI 0.60-0.71), a slightly lower specificity, 0.92 (95% CI 0.90-0.95) and a good agreement, κ = 0.61 (95% CI 0.55-0.67). In multivariate logistic regression analysis, offspring not having children was a predictor for discrepant answers (odds ratio [OR] 2.11 [95% CI 1.21-3.69]). Low amount of parents' tobacco consumption, < 10 cigarettes/day (OR 2.72 [95% CI 1.71-4.31]) also predicted disagreement compared to ≥10 cigarettes per day, and so did offspring's reports of fathers' smoking status (OR 1.73 [95% CI 1.09-2.74]) compared to mothers' smoking status. Offspring's sex, asthma status, educational level, smoking status or age was not related to discrepant answers.

CONCLUSIONS: Adults report their parent's smoking status during their childhood, as well as their mother' smoking status when pregnant with them, quite accurately. In the absence of parents' direct report, offspring's reports could be valuable.

OriginalsprogEngelsk
TidsskriftBMC Public Health
Vol/bind19
Nummer1
Sider (fra-til)94
Antal sider9
ISSN1471-2458
DOI
StatusUdgivet - 21 jan. 2019

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