Department of Clinical Medicine

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Søren Nielsen

Dr.med., Klinisk professor, overlæge, dr.med.

Curriculum Vitae

CURRICULUM VITAE

Søren Nielsen, overlæge, lektor, dr. med.

 

AUTORISATIONER:

Speciallæge i intern medicin:endokrinologi                                                       September 2005

Speciallæge i medicinsk endokrinologi                                                              August 2003

Tilladelse til selvstændig virke som læge                                                           Februar 1992

Autorisation som læge                                                                                     Januar 1987

 

UDDANNELSE:

Kursusstilling, Intern medicin                                                                          September 2000

United States Medical Licensing Examination - Step 2,

Minneapolis, USA                                                                                            April 1997

United States Medical Licensing Examination – Step 1,

Minneapolis, USA                                                                                            December 1996

Lægevidenskabelig kandidateksamen, Århus Universitet                                   Januar 1987

Studentereksamen (mat-fys), Kolding Gymnasium                                                                 Juni 1978

 

AKADEMISKE UDNÆVNELSER:

Adjungeret lektor, Det Sundhedsvidenskabelige Fakultet, Århus Universitet     December 2009

Dr. med., Det Sundhedsvidenskabelige Fakultet, Århus Universitet                  

          Disputats: Microalbuminuria in Type 2 Diabetes.

          Relationship with Renal Function, Insulin Resistance, and

          Vascular Dysfunction.                                                                           Oktober 2002

Cand. med., Det Sundhedsvidenskabelige Fakultet Århus Universitet                Januar 1987

 

HÆDERSBEVISNINER:

Købmand Bernhard og Metha Rasmussens Fond                                               2005

Ingeborg Maibølls Legat                                                                                   2004

Holger Bagger Sørensen Legatet                                                                       2003

Gårdejer af Stenløse Peder Laurits Petersens Legat                                                                  1993

 

MEDLEMSKABER:

American Diabetes Assocoation

Dansk Endokrinologisk Selskab

Dansk Thyroidea Selskab

 

SENESTE VÆSENTLIGE ANSÆTTELSER:

Reservelæge, Ortopædkirurgisk afdeling, Kolding Sygehus.

1. februar 1987 - 30. april 1987 (3 mdr)

 

Reservelæge, Klinisk fysiologisk afdeling, Ålborg Sygehus Syd.

1. maj 1987 - 31. januar 1988 (9 mdr)

 

Reservelæge, Urologisk afdeling K, Århus Kommunehospital.

1.februar 1988 - 31. juli 1988 (6 mdr)

 

Reservelæge, Medicinsk afdeling M, Århus Kommunehospital.

1. august 1988 - 31. juli 1990 (24 mdr)

 

Klinisk assistent, Medicinsk afdeling M, Århus Kommunehospital.

1. august 1990 - 31. maj 1994 (46 mdr)

 

1. Reservelæge, Medicinsk afdeling V, Århus Kommunehospital.

1. juni 1994 - 31. august 1994 (3 mdr)

 

Klinisk assistent, Medicinsk afdeling M, Århus Kommunehospital.

1. september 1994 - 31. januar 1996 (17 mdr)

 

Reservelæge, Medicinsk afdeling V, Århus Kommunehospital.

1. februar 1996 - 31. august 1996 (7 mdr)

 

Senior Research Fellow, Endocrine Research Unit, Mayo Clinic and Foundation, Rochester, Minnesota, USA.

1. september 1996 - 31. august 1998 (24 mdr)

 

Kursus reservelæge, Medicinsk afdeling M, Århus Kommunehospital.

1. september 1998 - 30 april 1999 (8 mdr)

 

Kursus reservelæge, Rheumatologisk afdeling U, Århus Kommunehospital.

1. maj 1999 - 31. december 1999 (8 mdr)

 

Kursus reservelæge, Medicinsk afdeling V, Århus Kommunehospital.

1. januar 2000 - 31. august 2000 (8 mdr)

 

Reservelæge, Rheumatologisk afdeling U, Århus Kommunehospital

1. september 2000 - 30. november 2000 (3 mdr)

 

1. Reservelæge, Medicinsk afdeling M, Århus Kommunehospital

1. december 2000 - 30. november 2003 (36 mdr)

 

1. Reservelæge, Medicinsk afdeling, Horsens Sygehus

1. december 2003 - 29. februar 2004 (3 mdr)

 

Klinisk assistent, Medicinsk afdeling M, Århus Sygehus

1. marts 2004 – 31. marts 2004 (1 mdr)

 

Afdelingslæge, Medicinsk afdeling M, Århus Sygehus

1. april 2004 - 31. marts 2007 (36 mdr)

 

Overlæge, Medicinsk afdeling M, Århus Sygehus

1. april 2007- 31.maj 2009

 

Overlæge / Forskningsstipendiat (Novo Nordisk Fonden), Medicinsk afdeling M, Århus Sygehus

1. juni 2009 -

 

UNDERVISNING:

Klinisk lektor i Intern Medicin, Det lægevidenskabelige Fakultet, Århus Universitet.

1. januar 1990 - 31. januar 1991; 1. januar 1995 - 31. juni 1995

 

Undervisningsassistent i Speciel Histologi, Det lægevidenskabelige Fakultet, Århus Universitet.

1. februar 1995 - 30. juni 1996

 

Ph.D. kursus i Sundhedsvidenskab: Eksperimentiel Biologisk og Molekylærbiologisk Forskning, Humane Helkropsmodeller. 14. juni 1999

 

Clinical intervention research in diabetes mellitus (DIRAC): Aspects of studies on in vivo lipid metabolism. 21. nov 2005

 

Klinisk lærer, Medicinsk afdeling V/M, Århus Kommunehospital.

1. februar 2000 - 30. juni 2000; 1. december 2000 - 30. november 2003; 1. april 2004 -

 

Systematiske morgenforelæsninger, Thyreotoxicose og myxødem, Det Sundhedsvidenskabelige Fakultet, Århus Universitet. August 2009 –

 

PhD kursus, Lipids and adipose tissue metabolism: Introduction to lipid metabolic isotope research techniques. Isotope dilution, indirect calorimetry, clamp technique, arterio-venous differences. Maj 2012

 

PhD kursus, Clinical assessment of insulin resistance and other metabolic parameters: Measurements of triglyceride turnover in human skeletal muscle.  April 2013

 

VEJLEDER:

  1. 2003-2007: Ph.D. stud. Lars Christian Gormsen. Aspekter af den humane lipid metabolisme med særlig vægt på FFA.

 

  1. 2003 – 2008: Ph.D. stud. Morten Kragh. Interaktionen mellem lipolyse, insulinfølsomhed og væksthormon i den humane metabolisme.

 

  1. 2006 – 2007: Forskningsårsstuderende, stud. med. Birgitte Nellemann Sørensen. Regional VLDL-triglycerid optagelse i fedtvæv hos overvægtige kvinder med abdominal og femoral fedtfordeling. Relationer med lipoprotein lipase aktivitet, VLDL-triglycerid turnover, blood-flow og fedtcelle størrelse.

 

  1. 2007 - 2011: Ph.D. stud. Lars Peter Sørensen: VLDL-triglycerid metabolisme ved visceral fedme og type 2 diabetes mellitus.

 

  1. 2008 - 2009: Forskningsårsstuderende, stud. med. Iben Rahbæk Andersen. Effekten af fysisk træning og muskel lipoprotein lipase aktivitet på VLDL-triglycerid oxidation og intramyocellulært triglycerid hos raske personer og patienter med type 2 diabetes mellitus.

 

  1. 2008 - 2011: Ph.D. stud. Esben Søndergaard. Systemisk og regional VLDL-triglycerid metabolisme. Effekt af postprandial insulinæmi og fysisk træning hos personer med hypertriglyceridæmi og forskellige typer overvægt.

 

  1. 2010 – 2013 Ph.D. stud Kia Halschou-Jensen: Disakkaridase-hæmmende komponenter i sukkerroen.

 

  1. 2010- 2014 Ph.D. stud. Birgitte Nellemann: Eksperimentel anti-lipolyse i humane modeller: effekt på akut aerob exercise, VLDL-TG omsætning og ghrelin induceret insulin resistens.

 

  1. 2011- 2014 Ph.D. stud. Marianne Kjær Poulsen: Lipidomsætning ved nonalkoholisk fedtlever. Effekt af resveratrol på leverfedtindhold samt basal og insulinstimuleret FFA og VLDL-triglycerid metabolisme hos overvægtige og morbidt overvægtige.

 

  1. 2012 – 2015 Ph.D. stud. Rakel Johansen: Effekt af diabetes og isoleret hyperglycæmi på VLDL1- og VLDL2-triglycerid omsætning.

 

  1. 2013 – Post doc, cand. med., PhD Esben Søndergaard. Postprandial VLDL-TG kinetics and metabolism in type 2 diabetes mellitus

 

 

FAGLIGE TILLIDSHVERV:

Medlem af Diabetesforeningens ældreudvalg.

1. december1991 – 1 september 1996

 

BIBLIOGRAFI

 

 

Publikationer                     

 

 

1.         S Nielsen, P Rødbro: Validity of rapid estimation of erythrocyte volume in the diagnosis of polycytemia vera. Eur J Nucl Med 1989; 15: 32-37.

 

2.         B Mathiassen, S Nielsen, J Ditzel, P Rødbro: Long-term bone loss in insulin-dependent diabetes mellitus. J Intern Med 1990; 227: 325-327.

 

3.         B Mathiassen, S Nielsen, J Johansen, D Hartwell, J Ditzel, P Rødbro, C Christiansen: Long term bone loss in insulin-dependent diabetic patients with microvascular complications. J Diabetic Compl 1990; 4: 145-149.

 

4.         CE Mogensen, EM Damsgaard, A Frøland, KW Hansen, S Nielsen, M Mau Pedersen, A Schmitz, L Thuesen, R Østerby: Reduced glomerular filtration rate and cardiovascular damage in diabetes: a key role for abnormal albuminuria. Acta Diabetologica 1992; 29: 201-213.

 

5.         CE Mogensen, EM Damsgaard, A Frøland, S Nielsen, N de Fine Olivarius, A Schmitz: Microalbuminuria in non-insulin-dependent diabetes. Clin Nephrology 1992; 38 (suppl 1): S28-S38.

 

6.         CE Mogensen, KW Hansen, S Nielsen, M Mau Pedersen, M Rehling, A Schmitz. Monitoring diabetic nephropathy: Glomerular filtration rate and abnormal albuminuria in diabetic renal disease: Reproducibility, progression studies and efficacy of antihypertensive intervention. Am J Kidney Dis 1993; 22: 174-187.

 

7.         S Nielsen, O Schmitz, N Møller, N Pørksen, IC Klausen, KGMM Alberti, CE Mogensen: Renal function and insulin sensitivity during simvastatin treatment in Type 2 (non-insulin-dependent) diabetic patients with microalbuminuria. Diabetologia 1993; 36: 1079-1086.

 

8.         S Nielsen, A Schmitz, M Rehling, CE Mogensen: Systolic blood pressure relates to the rate of decline of glomerular filtration rate in Type 2 diabetes. Diabetes Care 1993; 16: 1427-1432.

 

9.         S Nielsen, A Schmitz, RE Knudsen, J Dollerup, CE Mogensen. Enalapril versus bendroflumethiazide in type 2 diabetes complicated by hypertension: Effects on blood pressure, metabolic control and urinary albumin excretion. Q J Med 1994; 87: 747-754.

 

10.       S Nielsen, O Schmitz, H Ørskov, CE Mogensen. Similar insulin sensitivity in non-insulin-dependent diabetic patients with normo- and microalbuminuria. Diabetes Care 1995; 18: 834-842.

 

11.       S Nielsen, K Hermansen, OW Rasmussen, C Thomsen, CE Mogensen. Urinary albumin excretion rate and 24 hour ambulatory blood pressure in non-insulin dependent diabetes with microalbuminura: Effects of a monounsaturated-enriched diet. Diabetologia 1995; 9: 1069-1075.

 

12.       S Nielsen, A Schmitz, PL Poulsen, KW Hansen, CE Mogensen. Albuminuria and 24 hour ambulatory blood pressure in normo- and microalbuminuric NIDDM patients. A longitudinal study. Diabetes Care 1995; 18: 1434-1441.

 

13.       S Nielsen, A Schmitz, FHM Derkx, CE Mogensen. Prorenin and renal function in NIDDM patients with normo- and microalbuminuria. J Intern Med 1995; 238: 499-505.

 

14.       N Møller, S Nielsen, B Nyholm, N Pørksen, KGMM Alberti, J Weeke. Glucose turnover, fuel oxidation and forearm substrate exchange in patients with thyrotoxicosis before and after medical treatment. Clin Endocrinology 1996; 44: 453-459.

 

15.       B Nyholm, A Mengel, S Nielsen, C Skjærbæk, N Møller, KGMM Alberti, O Schmitz. Insulin resistance of relatives of patients with NIDDM: the role of physical capacity, muscle blood flow and metabolism. Diabetologia1996; 813-822.

 

16.       S Nielsen, A Schmitz, M Rehling, CE Mogensen. The clinical course of renal function in NIDDM patients with normo- and microalbuminuria. J Intern Med 1997; 241: 133-141.

 

17.       S Nielsen, MD Jensen. Obesity and cardiovascular disease: is body structure a factor? Current Opinion in Lipidology 1997; 8:200-204.

 

18.       S Nielsen, J Dollerup, B Nielsen, HÆ Jensen, CE Mogensen. Losartan reduces albuminuria in patients with essential hypertension. An enalapril controlled 3 months study. Nephrol Dial Transplant1997 12 [Suppl 2]: 19-23.

 

19.       Z Guo, S Nielsen, B Burguera, MD Jensen. Free fatty acid turnover measured using ultralow doses of [u-13C]palmitate. J Lipid Res 1997; 38: 1888-1895.

 

20.       B Nyholm, A Mengel, S Nielsen, CB Skjærbæk, N Møller, KGMM Alberti, OE Schmitz. Insulin resistens hos slægtninge til patienter med NIDDM. Ugeskrift for læger 1998; 160: 410-415

 

21.       N Møller, KY Hove, S Nielsen, B Nyholm, NK Pørksen, J Weeke. Substratomsætning ved tyreotoxicose før og efter medicinsk behandling. Ugeskrift for læger 1998; 160: 1475-1479.

 

22.       S Nielsen, J Dollerup, B Nielsen, CE Mogensen.Combination of enelapril and low-dose thiazide reduces normoalbuminuria in essential hypertension. J Hypertens 1998; 16: 1539-1544.

 

23.       S Nielsen, A Schmitz, T Bacher, M Rehling, J Ingerslev, CE Mogensen. Transcapillary escape rate and albuminuria in Type 2 diabetes. Effects of short-term treatment with low-molecular weight heparin. Diabetologia 1999; 42: 60-67.

 

24.       S Nielsen, M Rehling, A Schmitz, CE Mogensen. Validity of rapid esitmation of  glomerular filtration rate in Type 2 diabetic patients with normal renal function. Nephrol Dial Transplant 1999; 14: 615-619. Comment in:Nephrol Dial Transplant 1999 Dec;14(12):2964-5

 

25.       MD Jensen, D Hensrud, PC O’Brien, S Nielsen. Collection and interpretation of plasma leptin concentration data in humans. Obesity Res 1999; 7:241-245.

 

26.       S Nielsen, MD Jensen. Relationship between urinary albumin excretion, body composition and hyperinsulinemia in normotensive, glucose tolerant adults. Diabetes Care 1999; 22: 1728-1733.

 

27.       H Nørrelund, KY Hove, Brems-Dalgaard E, AG Jurik, LP Nielsen, S Nielsen, JO Jørgensen, J Weeke, N Møller. Muscle mass and function in thyrotoxic patients before and during medical treatment. Clin Endocrinol 1999; 51: 693-699.

 

28.       S Nielsen, DD Hensrud, S Romanski, JA Levine, B Burguera, MD Jensen. Body composition and resting energy expenditure in humans: Role of fat, fat free mass and extracellular fluid. Int J Obesity 2000; 24: 1153-1157.

 

29.       S Nielsen, KY Hove, J Dollerup, PL Poulsen, JS Christiansen, O Schmitz, CE Mogensen. Losartan modifies glomerular hyperfiltration and insulin sensitivity in type 1 diabetes. Diabetes Obesity Metab 2001; 3: 463-471.

 

30.       S Nielsen, JB Lundemose, M Simonsen, C Dragsholt. Letalt forløbende ecstasy forgiftning. Ugeskrift for Læger 2001; 163: 2253-2255.

 

31.       S Nielsen, J Levine, R Clay, MD Jensen. Adipose tissue metabolism in Benign Symmetric Lipomatosis. J Clin Endocrinol Metab 2001; 86: 2717-2720.

 

32.       CB Djurhuus, CH Gravholt, S Nielsen, A Mengel, JS Christiansen, OE Schmitz, N Møller. Effects of cortisol on lipolysis and regional interstitial glycerol levels in humans. Am J Physiol Endocrinol Metab 2002; 283: E172-E177.

 

33.       JF Nielsen, H Andersen, S Nielsen. Increased cortical inhibition in non-insulin dependent diabetic patients. Int J Diabetes & Metabolism 2002; 10:124-129.

 

34.       S Nielsen, Z Guo, JB Albu, S Klein, PC O’Brien, MD Jensen. Energy expenditure, sex, and endogenous fuel availability in humans. J Clin Invest 2003; 111: 981-988.

 

35.       H Nørrelund, C Djurhuus, JOL Jørgensen, S Nielsen, KS Nair, O Schmitz, JS Christiansen, N Møller.Effects of GH on urea, glucose and lipid metabolism, and insulin sensitivity during fasting in GH-deficient patients. Am J Physiol Endocrinol Metab 2003; 285(4):E737-E743.

 

36.       CB Djurhuus, CH Gravholt, S Nielsen, N Møller, O Schmitz. Additive effects of Cortisol  and Growth hormone on regional and systemic lipolysis in humans Am J Physiol Endocrinol Metab 2004; 286(3):E488-494.

 

37.       B Nyholm, MF Nielsen, K Kristensen, S Nielsen, T Østergård, SB Pedersen, T Christiansen, B Richelsen, MD Jensen O Schmitz. Evidence of visceral obesity and reduced physical fitness in healthy insulin resistant first degree relatives of type 2 diabetic patients. Eur J Endocrinol 2004; 150: 207-214.

 

38.       S Nielsen, AS Lihn, T Østergaard, CE Mogensen, O Schmitz. Increased plasma adiponectin in losartan treated type 1 diabetic patients. A mediator of improved insulin sensitivity? Horm Metab Res 2004; 36: 194-196.

 

39.       H Andersen, S Nielsen, CE Mogensen, J Jakobsen. Muscle strength in type 2 diabetes. Diabetes2004; 53: 1543-1548.

 

40.       S Nielsen, Z Guo, M Johnson, DD Hensrud, MD Jensen. Splanchnic lipolysis in human obesity. J Clin Invest2004; 113: 1582-1588.

 

41.       S Nielsen, JR Halliwill, MJ Joyner, MD Jensen. Vascular response to angiotensin II in upper body obesity. Hypertension2004; 44: 435-441.

 

42.       H Andersen, O Schmitz, S Nielsen. Decreased isometric muscle strength after acute hyperglycemia in type 1 diabetic patients. Diabetic Med 2005; 1401-1407.

 

43.       LC Gormsen, MD Jensen, S Nielsen. Measuring VLDL-triglycerides turnover in humans using ex-vivo prepared VLDL tracer.J Lipid Res 2006; 47: 99-106.

 

44.       H Andersen, S Nielsen, J Nielsen. Motor cortical excitability remains unaffected of short-term hyperglycemia in Type 1 diabetic patients. J Diabetes Compl 2006; 20: 51-55.

 

45.       LC Gormsen, J Gjedsted, S Gjedde, ET Vestergaard, JS Christiansen, JO Jørgensen, S Nielsen, N Møller. Free fatty acids decrease circulating ghrelin concentrations in humans. Eur J Endocrinol2006;154: 667-673.

 

46.       LC Gormsen, MD Jensen, O Schmitz, N Møller, JS Christiansen, S Nielsen. Energy expenditure, insulin and VLDL-triglyceride turnover in humans.J Lipid Res 2006; 47: 2325-2332.

 

47.       MD Jensen, S Nielsen. Insulin dose response analysis of free fatty acid kinetics. Metabolism Clin Exp2007; 56: 68-76.

 

48.       M Krag, LC Gormsen, Z Guo, JS Christiansen, MD Jensen, S Nielsen, JOL Jørgensen. Growth hormone-induced insulin resistance is associated with inceased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics. Am J Physiol Endocrinol Metab2007; 292: E920-E927.

 

49.       LC Gormsen, N Jessen, J Gjedsted, S Gjedde, H Nørrelund, S Lund, JS Christiansen, S Nielsen, O Schmitz, N Møller. Dose-response effects of free fatty acids on glucose and lipid metabolism during somatostatin blockade of growth hormone and insulin in humans. J Clin Endocrinol Metab 2007 92: 1834-1842.

 

50.       R Lindberg-Larsen, N Møller, O Schmitz, S Nielsen, M Andersen, H Ørskov, JOL Jørgensen The impact of pegvisomant treatment on substrate metabolism and insulin sensitivity in patients with acromegaly. J Clin Endocrinol Metab 2007; 92:1724-1728.

 

51.       P Laurberg, H Vestergaard, S Nielsen, SE Christensen, T Seefeldt, K Helleberg, KM Pedersen. Sources of circulating T3 in hyperthyroidism estimated after blocking of type 1 and type 2 iodothyronine deiodinases. J Clin Endocrinol Metab2007; 92:2149-2156.

 

52.       J Gjedsted, LC Gormsen, S Nielsen, O Schmitz, Djurhuus CB, S Keiding, H Ørskov, E Tønnesen, N Møller. Effects of a 3-day fast on regional lipid and glucose metabolism in human skeletal and adipose tissue. Acta Physiologica2007; 191:205-216.

 

53.       B Nellemann, LC Gormsen, J Dollerup, O Schmitz, CE Mogensen, LM Rasmussen, S Nielsen. Simvastatin reduces plasma osteoprotegerin in type 2 diabetic patients with microalbuminuria. Diabetes Care2007; 30:3122-3124

 

54.       ET Vestergaard, CB Djurhuus, J Gjedsted, S Nielsen, N Møller, JJ Holst, JOL Jørgensen, O Schmitz. Acute effects of ghrelin administration on glucose and lipid metabolism J Clin Endocrinol Metab2008;93:438-444.

 

55.       MB Krag, S Nielsen, Z Guo, SB Pedersen, O Schmitz, JS Christiansen, JOL Jørgensen. Peroxisome proliferator-activated receptor gamma agonism modifies the effects of growth hormone on lipolysis and insulin sensitivity. Clin Endocrinol2008; 69:452-461.

 

56.       Møller, N., Poulsen, P.L., Nielsen, S., Mogensen, C.E. Measurement of postprandial blood glucose level and the necessary difference between the valuable and invaluable | [Om måling af postprandiale blodsukkervaerdier og den nødvendige sondring mellem det lødige og det overlødige.] Ugeskrift for laeger 2008 170 (17), pp. 1483  

 

57.       LC Gormsen, B Nellemann, LP Sørensen, MD Jensen, JS Christiansen, S Nielsen. Impact of Body Composition on Very-Low-Density-Lipoprotein-Triglycerides Kinetics. Am J Physiol Endocrinol Metab 2009; 296:165-173

                     

58.       E Søndergaard, LC Gormsen, B Nellemann, ET Vestergaard, JS Christiansen, S Nielsen. Visceral fat mass is a strong predictor of circulating ghrelin levels in premenopausal women. Eur J Endocrinol2009; 160:375-379

 

59.       MD Jensen, J Bajnárek, SY Lee, S Nielsen, C Koutsari. Relationship between postabsorptive respiratory exchange ratio and plasma free fatty acid concentrations. J Lipid Res2009; 50:1863-1869

 

60.       LP Sørensen, LC Gormsen, S Nielsen. VLDL-TG kinetics: a dual isotope study for quantifying VLDL-TG pool size, production rates and fractional oxidation in humans.  Am J Physiol Endocrinol Metab 2009; 297:E1324-E1330

 

61.       B Nellemann, LC Gormsen, JS. Christiansen, MD Jensen, S Nielsen. Postabsorptive VLDL-TG Fatty Acid Storage in Adipose Tissue in Lean and Obese Women. Obesity2010; 18:1304–1311

 

62.       LP Sørensen, B Brock, A Mengel, J Rungby, N Møller, S Nielsen, A Vølund, O Schmitz. Similarity of pharmacodynamic effects of a single injection of insulin glargine, insulin detemir and NPH insulin on glucose metabolism assessed by 24-h euglycaemic clamp studies in healthy humans. Diabet Med 2010; 27:830-837

 

63.       LC Gormsen, C Høst, BE Hjerrild, CH Gravholt, S Nielsen. Acute estrogen exposure does not affect basal VLDL-TG production or oxidation in post-menopausal women. Eur J Endocrinol 2010; 163:421-426

 

64.       S Gjedde, LC Gormsen, J Rungby, S Nielsen, JOL Jørgensen, SB Pedersen, AL Riis, J Weeke, N Møller. Decreased lipid intermediate levels and lipid oxidation rates despite normal lipolysis in patients hypothyroidism. Thyroid 2010; 20:843-849

 

65.       LP Sørensen, IR Andersen, E Søndergaard, LC Gormsen, O Schmitz, JS Christiansen, S Nielsen. Basal and insulin mediated VLDL-triglyceride kinetics in type 2 diabetic men. Diabetes 2010; 60:88–96, 2011

 

66.       ET Vestergaard, M Buhl, J Gjedsted, M Madsen, N Jessen, S Nielsen, BD Gaylinn, J Liu, MO Thorner, N Møller, JOL Jørgensen. Acute Peripheral Metabolic Effects of Intraarterial Ghrelin Infusion in Healthy Young Men. J Clin Endocrinol Metab 2011; 96:468-477

 

67.       E Søndergaard, I Rahbek, LP Sørensen, JS Christiansen, LC Gormsen, MD Jensen, S Nielsen. Effects of exercise on VLDL-triglyceride oxidation and turnover. Am J Physiol Endocrinol Metab 2011; 300:E939-E944

 

68.       J Gjedsted, M Buhl, S Nielsen, O Schmitz, ET Vestergaard, E Tønnesen, N Møller. Effects of adrenaline on lactate, glucose, lipid and protein metabolism in the placebo controlled bilaterally perfused human leg.Acta Physiologica 2011; 202:641-648

 

69.       T Krusenstjerna-Hafstrøm, ET Vestergaard, M Buhl, R Nielsen, BF Clasen, S Nielsen, N Møller, SB Pedersen, JOL Jørgensen.Acute Peripheral Metabolic Effects of Intraarterial Leg Infusion of Somatostatin in Healthy Young Men. J Clin Endocrinol Metab 2011; 96:2581-2589

 

70.       LP Sørensen, E Søndergaard, B Nellemann, JS Christiansen, LC Gormsen, S Nielsen. Increased VLDL-TG Secretion Precedes Impaired Control of Endogenous Glucose Production in Obese, Normoglycaemic Men. Diabetes 2011; 60:2257-2264

 

71.       E Søndergaard, B Nellemann, LP Sørensen, LC Gormsen, JS Christiansen, E Ernst, M Dueholm, S Nielsen. Similar VLDL-TG Storage in Visceral and Subcutaneous Fat in Obese and Lean Women. Diabetes 2011; 60:2787-2791

 

72.       B Nellemann, LC Gormsen, JS Christiansen, LP Sørensen, S Nielsen. Impaired Insulin Mediated Antilipolysis and Lactate Release in Adipose Tissue of Upper-body Obese Women. Obesity 2012; 20: 57-64

 

73.       MD Jensen, S Nielsen, N Gupta, R Basu, R Rizza. Insulin clearance is different in men and women.  Metabolism Clin Exp2012; 61:525-530

 

74.       R Nielsen, H Wiggers, M Halbirk, HE Bøtker, J Holst, O Schmitz, E Frandsen, S Nielsen, N Møller, H Nørrelund. Metabolic Effects of Short-term GLP-1 Treatment in Insulin Resistant Heart Failure Patients. Exp Clin Endocrinol & Diabetes 2012; 120:266-272

 

75.       T Parkner, LP Sørensen, AR Nielsen, CP Fischer, BM Bibby, S Nielsen, BK Pedersen, HJ Møller. Soluble CD163 – a biomarker linking macrophages and insulin resistance. Diabetologia 2012; 55:1856-1862

 

76.       E Søndergaard, LC Gormsen, B Nellemann, MD Jensen, S Nielsen. Body composition determines direct FFA storage pattern in overweight women. Am J Physiol Endocrinol Metab 2012; 302:E1599-E1604.

 

77.       S Nielsen, F Karpe. Determinants of VLDL-TG production. Curr Opin Lipidol 2012; 23:321-326

 

78.       E Søndergaard, LP Sørensen, I Rahbek, LC Gormsen, JS Christiansen, S Nielsen. Postprandial VLDL-triacylglycerol secretion is not suppressed in obese type 2 diabetic men. Diabetologia 2012; 55:2733-40

 

79.       L Gormsen, C Høst, BE Hjerrild, SB Pedersen, S Nielsen, JS Christiansen, CH Gravholt. Estradiol acutely inhibits whole body lipid oxidation and attenuates lipolysis in subcutaneous adipose tissue: A randomized, placebo controlled study in post-menopausal women. Eur J Endocrinol 2012;  167:543-51

 

80.       C Høst, LC Gormsen, B Christensen, N Jessen, DM Hougaard, JS Christiansen, SB Pedersen, Jensen MD, S Nielsen, CH Gravholt. Independent effects of testosterone on lipid oxidation and VLDL-TG production. A randomized, double-blind, placebo-controlled, cross-over study Diabetes 2013; 62:1409-1416

 

81.       S Nielsen, AE Sumner, BV Miller 3rd, H Turkova, S Klein, MD Jensen. Free Fatty Acid Flux in African American and Caucasian Adults – Effect of Sex and Race Obesity 2013; 21:1836-1842

 

82.       B Christensen, B Nellemann, M Larsen, L Thams, P Sieljacks, P Vestergaard, B Bibby, K Vissing, H Stødkilde-Jørgensen, S Pedersen, N Møller, S Nielsen, N Jessen, JO Jørgensen. Whole body metabolic effects of prolonged endurance training in combination with erythropoietin treatment in humans: a randomized placebo controlled study. Am J Physiol Endocrinol Metab 2013; 305:E879-E889

 

83.       E Søndergaard, MK Poulsen, MD Jensen, S Nielsen. Acute changes in lipoprotein subclasses during exercise. Metabolism 2014; 63:61-68

 

84.       B Nellemann, E Søndergaard, J Jensen, SB Pedersen, N Jessen, JOL Jørgensen, S Nielsen.

Kinetics and utilization of lipid sources during acute exercise and acipimox. Am J Physiol Endocrinol Metab 2014; 307:E199–E208

 

85.       E Søndergaard, LC Gormsen, MH Christensen, SB Pedersen, P Christiansen, S Nielsen, PL Poulsen, N Jessen. Chronic adrenergic stimulation induces brown adipose tissue differentiation in visceral adipose tissue. Diabetic Med 2015; 32:e4-8

 

86.       B Nellemann, B Christensen, K Vissing, L Thams, P Sieljacks, M Larsen, JO Jørgensen, S Nielsen.Ten weks of aerobic training does not result in persistent changes in VLDL triglyceride turnover or oxidation in healthy men. Eur J Endocrinol2014;171:603-613

 

87.       RF Johansen, E Søndergaard, LP Sørensen, B Nellemann, JS Christiansen, S Nielsen. Isolated Hyperglycemia does not Increase VLDL-TG Secretion Rate in Type 1 Diabetic Men. Diabetologia 2015; 58:355-362

 

88.       K Halschou-Jensen, KE Knudsen, S Nielsen, K Bukhave, JR Andersen. A mixed diet supplemented with l-arabinose does not alter glycaemic or insulinaemic responses in healthy human subjects. Brit J Nutr 2014; 17:1-7

 

89.       LP Sørensen, T Parkner, E Søndergaard, BM Bibby, HJ Møller, S Nielsen. Visceral obesity is associated with increased soluble CD163 concentration in men with type 2 diabetes mellitus Endocrine Connections2015; 4:27-36

 

90.       J Fjølner, E Søndergaard, U Kampmann, S Nielsen. Complete recovery after severe myxoedema coma complicated by status epilepticus. BMJ Case Reports 2015 (Epub ahead of print)

 

91.       E Søndergaard, B Nellemann, LP Sørensen, B Christensen, LC Gormsen, S Nielsen. Lean body mass, not FFA, predicts VLDL-TG secretion rate in healthy men Obesity2015; 23:1379-85

 

92.       MK Poulsen, B Nellemann, H Stødkilde-Jørgensen, SB Pedersen, H Grønbæk, S Nielsen.  Impaired Insulin-mediated Very-Low-Density-Lipoprotein-triglyceride Kinetics in Obese men with Non-alcoholic Fatty Liver Disease (in press)

 

93.       RF Johansen, E Søndergaard, LP Sørensen, AG Jurik, JS Christiansen, S Nielsen. Differential Regulation of VLDL1 and VLDL2 Kinetics in Type 2 Diabetes (submitted)

 

94.       RF Johansen, E Søndergaard, LP Sørensen, MD, AG Jurik, JS Christiansen, S Nielsen. The effect of a provided isocaloric dietary control on day-to-day variation in VLDL1-TG and VLDL2-TG kinetics (in prep)

 

95.       MK Poulsen, B Nellemann, BM Bibby, H Stødkilde-Jørgensen, SB Pedersen, H Grønbæk, S Nielsen. No Effect of Long-term High-dose Resveratrol on VLDL-TG Kinetics, Insulin Sensitivity and Liver Fat Content in Obese men with Non-alcoholic Fatty Liver Disease (in prep) 

 

 

 

 

Bogkapitler:

 

1.         B Mathiassen, S Nielsen, J Johansen, D Hartwell, J Ditzel, P Rødbro, C Christiansen: Is bone loss accelerated in insulin-dependent diabetics with microvascular complications? In: Christiansen C, Overgaard K (eds): Osteoporosis 1990, Osteopress, Copenhagen, pp 1605-1607.

 

2.         CE Mogensen, EM Damsgaard, N de Fine Olivarius, A Fröland, S Nielsen, A Schmitz, O Schmitz, E Vestbo. Microalbuminuria, elevated blood pressure and the metabolic syndrome. In: G Crepaldi, A Tiengo, E Manzato (eds). Diabetes, obesity and hyperlipidemias: V. The plurimetabolic syndrome. Amsterdam, London, New York, Tokyo; Elsevier Science Publishers B.V. 1993; 127-131.

 

3.         S Nielsen, A Schmitz. The clinical course of renal disease in causian NIDDM patients. In: CE Mogensen (ed). The kidney and hypertension in diabetes mellitus (2nd ed). Boston, Dordrecht, London; Cluwer Academic Publishers 1994; pp 111-121.

 

4.         S Nielsen, A Schmitz. The clinical course of renal disease in causian NIDDM patients. In: CE Mogensen (ed). The kidney and hypertension in diabetes mellitus (3rd ed). Boston, Dordrecht, London; Cluwer Academic Publishers 1997; pp 143-153.

5.         S Nielsen, A Schmitz. The clinical course of renal disease in causian NIDDM patients. In: CE Mogensen (ed). The kidney and hypertension in diabetes mellitus (4th ed). Boston, Dordrecht, London; Cluwer Academic Publishers 1998; pp 73-83.

 

6          S Nielsen, A Schmitz. The clinical course of renal disease in causian NIDDM patients. In: CE Mogensen (ed). The kidney and hypertension in diabetes mellitus (5th ed). Boston, Dordrecht, London; Cluwer Academic Publishers 2000; pp 81-94