Søren Borg


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Søren Borg


  • Institut for Molekylærbiologi og Genetik - Afgrødegenetik og Bioteknologi
Forsøgsvej 1

E-mail: soren.borg@mbg.au.dk

Telefon: +4587158283


2010-nowLector, Department of Molecular Biology and Genetics, Faculty of Science and Technology, Aarhus University
2007-2010Senior Scientist, Department of Genetics and Biotechnology, Faculty of Agricultural Sciences, Aarhus University
1998-2006Scientist at Danish Institute of Agricultural Science, Research Centre Flakkebjerg
1996-1998Post doc., Laboratory of Geneexpression, Department of Molecular Biology, Faculty of Natural Sciences, Aarhus University, Funded by the Carlsberg foundation
1982-1986Teacher at Blæsenborg elementary school, Maribo

Education and Training

1996PhD in Molecular Biology, Aarhus University
1992 MSc in Molecular Biology, Aarhus University
1982Graduate as teacher from Vordingborg Seminarium

Scientific Summary

My main interests lie within the field of transport, content and bioavailability of minerals (iron and zinc) in plants. I work mainly in the important crop plant wheat and barley. I have substantial and documented experience in transformation of cereals, heterologous gene expression using laser capture microdissection, mineral uptake & transport and ferritin iron storage in plants.

Transport, content and bioavailability of iron and zinc in wheat and barley grain

Dietary iron and zinc deficiency is a global problem afflicting about one third of the world’s population. This results primarily from poverty that leads a too narrow food base consisting almost exclusively of inexpensive starch crops like wheat, maize and rice, crops that have a low content of minerals in the endosperm. The strategies utilised to combat this micronutrient malnutrition such as food fortification, mineral supplements and dietary diversifications are beneficial short-term solutions for effluent societies. However, in developing countries a long term, self-sustainable approach would be the enrichment of iron in staple food products by traditional plant breeding or modern genetic approaches.

Cisgenic ferritin wheat

To create the foundation for increasing the iron content of the wheat endosperm we have isolated and characterized the ferritin gene complement in wheat. In a cisgenic approach we have developed transgenic wheat plants that overexpress one of the wheat’s own ferritin genes in the endosperm and thereby increase the bioavailable iron content in the edible parts.

Bibliometric Summary

Total of 13 papers (peer-review)
Total number of citations: 321, H-index 8
Selected publications within the last 5 years:

Mikkelsen, M. D., Pedas, P., Schiller, M., Vincze, É., Mills, R. F., Borg, S., ... Palmgren, M. B. (2012). Barley HvHMA1 Is a Heavy Metal Pump Involved in Mobilizing Organellar Zn and Cu and Plays a Role in Metal Loading into Grains. P L o S One, 7(11). https://doi.org/10.1371/journal.pone.0049027
Borg, S., Brinch-Pedersen, H., Tauris, B., Madsen, L. H., Shirvanehdeh, B. D., Noeparvar, S., & Holm, P. B. (2012). Wheat ferritins: Improving the iron content of the wheat grain. Journal of Cereal Science, 56(2), 204-213. https://doi.org/10.1016/j.jcs.2012.03.005
Ortiz-Monasterio, I., Trethowan, R., Holm, P. B., Cakmak, I., Borg, S., Erenoglu, B., ... Brinch-Pedersen, H. (2010). Breeding, transformation, and physiological strategies for the development of wheat with high zinc and iron grain concentration. I A. Bonjean, W. Angus, & M. van Ginkel (red.), The World Wheat Book - a history of wheat breeding (Bind 2, s. 1-28). Lavoisier.
Tauris, B., Borg, S., Gregersen, P. L., & Holm, P. B. (2009). A roadmap for zinc trafficking in the developing barley grain based on laser capture microdissection and gene expression profiling. Journal of Experimental Botany, 60(4), 1333-1347. https://doi.org/10.1093/jxb/erp023
Borg, S., Brinch-Pedersen, H., Tauris, B., & Holm, P. B. (2009). Iron transport, deposition and bioavailability in the wheat and barley grain. Plant and Soil, 325(1-2), 15-24. https://doi.org/10.1007/s11104-009-0046-6
Palmgren, M. G., Clemens, S., Williams, L. E., Krämer, U., Borg, S., Schjørring, J. K., & Sanders, D. (2008). Zinc biofortification of cereals: problems and solutions. Trends in Plant Science, 13(9), 464-473. https://doi.org/10.1016/j.tplants.2008.06.005
Brinch-Pedersen, H., Borg, S., Tauris, B., & Holm, P. B. (2007). Molecular genetic approaches to increasing mineral availability and vitamin content of cereals. Journal of Cereal Science, 46, 308-326. https://doi.org/10.1016/j.jcs.2007.02.004

Invited presentation international scientific congresses

Tauris, B, Borg, S, Gregersen, PL & Holm, PB. Transport and Deposition of Zinc in the Developing Barley Grain, Zinc Crops 2007, Improving crop production and human health, Istanbul, Tyrkiet. 24.-26. May, 2007.
Darbani, B, Borg, S, Brinch-Pedersen, H & Holm, PB. Iron biofortification of grain of modern wheat cultivar. 15th International Symposium on Iron Nutrition and Interactions in Plants (ISINIP). June 25-30, 2010, Budapest, Hungary.
Borg, S, Darbani, B, Tauris, B, Noeparvar, S, & Holm, PB. Transport and Deposition of Iron and Zinc in the Wheat and Barley Grain. Second Annual Confrence in COST action FA 0905. Mineral Improved Crpo Production for Healthy Food and Feed. November 23-26, 2011, Venice, Italy.

International collaborations

Phime H and Cost.

Membership of societies, selected academic distinctions and other merits

Danish member of the Management Committee of FA Action COST FA0905: Mineral-improved crop production for healthy food and feed.

Teaching and supervision

Completed: 2 PhD
Birgitte Tauris, 2009, PhD
Behrooz Darbani, 2012, PhD
Currently supervising: 1 PhD
I have been involved in the planning and teaching several courses and I am currently teaching on the 5 ECTS BSc course “Molecular Biology of Plants”. In addition I am involved in the planning of the summer 2013 university MSc/ PhD course “Advanced techniques in plant science and biotechnology”.

Thesis evaluation/opponent

I have been the opponent of three PhD theses and the chairman of five PhD defenses.

Referee for scientific journals

Frequently reviewing manuscripts for international journals.

Managerial positions and committee work

Member of the departmental PhD program committee.

Knowledge exchange

Have over the last 10 years regularly been invited to visit and give oral presentations at elementary and high schools.