Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review
Validation of diagnostic codes for Charcot-Marie-Tooth disease in the Danish National Patient Registry. / Væth, Signe; Jensen, Uffe Birk; Christensen, Rikke et al.
I: Clinical Epidemiology, Bind 8, 2016, s. 783-787.Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review
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TY - JOUR
T1 - Validation of diagnostic codes for Charcot-Marie-Tooth disease in the Danish National Patient Registry
AU - Væth, Signe
AU - Jensen, Uffe Birk
AU - Christensen, Rikke
AU - Andersen, Henning
PY - 2016
Y1 - 2016
N2 - PURPOSE: To validate the diagnostic codes for Charcot-Marie-Tooth disease (CMT) in the Danish National Patient Registry (DNPR) using positive predictive value (PPV) as a measure of validity.PATIENTS AND METHODS: We used the DNPR to identify all patients diagnosed with at least one primary CMT diagnosis at a specialized department in the Central Denmark Region during the period 1977-2012. From this population, we randomly selected 123 patients for the validation study. Medical files were reviewed and used as reference standard. We estimated the PPV of the CMT diagnoses and stratified the analysis according to age at diagnosis, gender, and calendar time.RESULTS: In the DNPR, 275 patients were identified. We were able to retrieve 96 medical files from the random sample of 123 patients, and 85 CMT diagnoses were confirmed. The average age at diagnosis was 42.5 years, and 34% were female. The PPV was 88.5% (95% confidence interval: 80.4-94.1).CONCLUSION: The CMT diagnoses in the DNPR have high validity. The DNPR can be used as a data source for epidemiologic research on CMT.
AB - PURPOSE: To validate the diagnostic codes for Charcot-Marie-Tooth disease (CMT) in the Danish National Patient Registry (DNPR) using positive predictive value (PPV) as a measure of validity.PATIENTS AND METHODS: We used the DNPR to identify all patients diagnosed with at least one primary CMT diagnosis at a specialized department in the Central Denmark Region during the period 1977-2012. From this population, we randomly selected 123 patients for the validation study. Medical files were reviewed and used as reference standard. We estimated the PPV of the CMT diagnoses and stratified the analysis according to age at diagnosis, gender, and calendar time.RESULTS: In the DNPR, 275 patients were identified. We were able to retrieve 96 medical files from the random sample of 123 patients, and 85 CMT diagnoses were confirmed. The average age at diagnosis was 42.5 years, and 34% were female. The PPV was 88.5% (95% confidence interval: 80.4-94.1).CONCLUSION: The CMT diagnoses in the DNPR have high validity. The DNPR can be used as a data source for epidemiologic research on CMT.
U2 - 10.2147/CLEP.S115565
DO - 10.2147/CLEP.S115565
M3 - Journal article
C2 - 27920579
VL - 8
SP - 783
EP - 787
JO - Clinical Epidemiology
JF - Clinical Epidemiology
SN - 1179-1349
ER -