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Rune Nguyen Rasmussen

Bursting deep dorsal horn neurons: the pharmacological target for the anti-spastic effects of Zolmitriptan?

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  • Rune Rasmussen
  • Eva Maria Meier Carlsen, Københavns Universitet, Danmark

In a recent publication, Thaweerattanasinp et al. (J Neurophysiol 116: 1644–1653, 2016) investigated spinal cord injury and firing properties of deep dorsal horn neurons during NMDA or zolmitriptan application by employing electrophysiology in an in vitro spinal cord preparation. Deep dorsal horn neurons were classified into bursting, simple, or tonic firing groups,with bursting neurons showing NMDA and zolmitriptan sensitivity. We discuss the findings in a methodological framework and propose future experiments of importance for translating the results into physiological settings.

OriginalsprogEngelsk
TidsskriftJournal of Neurophysiology
Vol/bind117
Nummer5
Sider (fra-til)1841-1843
Antal sider3
ISSN0022-3077
DOI
StatusUdgivet - maj 2017

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