Aarhus University Seal / Aarhus Universitets segl

Preben Bo Mortensen

Investigating the causal relationship between neuroticism and depression via Mendelian Randomization

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisLetterForskningpeer review

  • Doug Speed
  • Gibran Hemani, Medical Research Council (MRC) Integrative Epidemiology Unit, University of Bristol, UK.
  • ,
  • Maria S Speed
  • Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium
  • ,
  • Anders D Børglum

Neuroticism is a heritable personality trait, characterized by negative emotions such as worrying, feelings of guilt, loneliness and being easily hurt. Increased levels of neuroticism are associated with poor mental health - development of depression in particular - but it remains uncertain whether this association represents a causal effect [1]. Here, we use Mendelian randomization (MR) to investigate whether neuroticism is a causal risk factor for development of depression. This article is protected by copyright. All rights reserved.

OriginalsprogEngelsk
TidsskriftActa Psychiatrica Scandinavica
Vol/bind139
Nummer4
Sider (fra-til)395-397
Antal sider3
ISSN0001-690X
DOI
StatusUdgivet - 2019

Se relationer på Aarhus Universitet Citationsformater

ID: 143204228