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Peter Vedsted

Testicular microlithiasis in patients with testicular cancer in the United Kingdom and in Denmark

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Standard

Testicular microlithiasis in patients with testicular cancer in the United Kingdom and in Denmark. / Pedersen, Malene Roland; Horsfield, Catherine; Foot, Oliver; Lindebjerg, Jan; Osther, Palle Jørn Sloth; Vedsted, Peter; Chandra, Ashish; Rafaelsen, Søren Rafael; Møller, Henrik.

I: Danish Medical Journal, Bind 65, Nr. 3, 03.2018.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Pedersen, MR, Horsfield, C, Foot, O, Lindebjerg, J, Osther, PJS, Vedsted, P, Chandra, A, Rafaelsen, SR & Møller, H 2018, 'Testicular microlithiasis in patients with testicular cancer in the United Kingdom and in Denmark', Danish Medical Journal, bind 65, nr. 3.

APA

Pedersen, M. R., Horsfield, C., Foot, O., Lindebjerg, J., Osther, P. J. S., Vedsted, P., ... Møller, H. (2018). Testicular microlithiasis in patients with testicular cancer in the United Kingdom and in Denmark. Danish Medical Journal, 65(3).

CBE

Pedersen MR, Horsfield C, Foot O, Lindebjerg J, Osther PJS, Vedsted P, Chandra A, Rafaelsen SR, Møller H. 2018. Testicular microlithiasis in patients with testicular cancer in the United Kingdom and in Denmark. Danish Medical Journal. 65(3).

MLA

Pedersen, Malene Roland o.a.. "Testicular microlithiasis in patients with testicular cancer in the United Kingdom and in Denmark". Danish Medical Journal. 2018. 65(3).

Vancouver

Pedersen MR, Horsfield C, Foot O, Lindebjerg J, Osther PJS, Vedsted P o.a. Testicular microlithiasis in patients with testicular cancer in the United Kingdom and in Denmark. Danish Medical Journal. 2018 mar;65(3).

Author

Pedersen, Malene Roland ; Horsfield, Catherine ; Foot, Oliver ; Lindebjerg, Jan ; Osther, Palle Jørn Sloth ; Vedsted, Peter ; Chandra, Ashish ; Rafaelsen, Søren Rafael ; Møller, Henrik. / Testicular microlithiasis in patients with testicular cancer in the United Kingdom and in Denmark. I: Danish Medical Journal. 2018 ; Bind 65, Nr. 3.

Bibtex

@article{de0bbde6d01b487fb7028a726ef066aa,
title = "Testicular microlithiasis in patients with testicular cancer in the United Kingdom and in Denmark",
abstract = "INTRODUCTION: Testicular cancer is the most common type of cancer in young Caucasian men. It has been suggested that testicular microlithiasis (TML) is a premalignant condition. This study's objective was to investigate TML histology prevalence in testicular cancer patients in two European populations.METHODS: We analysed archived histopathology orchiectomy specimens from 152 patients diagnosed with testicular cancer at Fredericia Hospital in Denmark from 2004 to 2014, and 106 patients diagnosed at St Thomas' Hospital in London from 2011 to 2015.RESULTS: The Danish patients' median age was 37 years (range: 16-74 years) and the English patients' 36 years (range: 18-78 years). In the Danish patients, 29 (19.1{\%}) had TML, and in the English patients, 43 (40.6{\%}) had TML (p < 0.001). Haematoxylin bodies were slightly more common in the English patients. Laminated calcification was more often seen in seminomas than in non-seminomas.
 CONCLUSIONS: The English testicular cancer patients had a statistically significantly higher TML prevalence than the Danish patients. This observation questions the hypothesised biological association between TML and testicular 
cancer.FUNDING: The Region of Southern Denmark supported this study.TRIAL REGISTRATION: not relevant.",
author = "Pedersen, {Malene Roland} and Catherine Horsfield and Oliver Foot and Jan Lindebjerg and Osther, {Palle J{\o}rn Sloth} and Peter Vedsted and Ashish Chandra and Rafaelsen, {S{\o}ren Rafael} and Henrik M{\o}ller",
note = "Articles published in the Danish Medical Journal are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.",
year = "2018",
month = "3",
language = "English",
volume = "65",
journal = "Danish Medical Bulletin (Online)",
issn = "1603-9629",
publisher = "Den Almindelige Danske L{\ae}geforening",
number = "3",

}

RIS

TY - JOUR

T1 - Testicular microlithiasis in patients with testicular cancer in the United Kingdom and in Denmark

AU - Pedersen, Malene Roland

AU - Horsfield, Catherine

AU - Foot, Oliver

AU - Lindebjerg, Jan

AU - Osther, Palle Jørn Sloth

AU - Vedsted, Peter

AU - Chandra, Ashish

AU - Rafaelsen, Søren Rafael

AU - Møller, Henrik

N1 - Articles published in the Danish Medical Journal are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

PY - 2018/3

Y1 - 2018/3

N2 - INTRODUCTION: Testicular cancer is the most common type of cancer in young Caucasian men. It has been suggested that testicular microlithiasis (TML) is a premalignant condition. This study's objective was to investigate TML histology prevalence in testicular cancer patients in two European populations.METHODS: We analysed archived histopathology orchiectomy specimens from 152 patients diagnosed with testicular cancer at Fredericia Hospital in Denmark from 2004 to 2014, and 106 patients diagnosed at St Thomas' Hospital in London from 2011 to 2015.RESULTS: The Danish patients' median age was 37 years (range: 16-74 years) and the English patients' 36 years (range: 18-78 years). In the Danish patients, 29 (19.1%) had TML, and in the English patients, 43 (40.6%) had TML (p < 0.001). Haematoxylin bodies were slightly more common in the English patients. Laminated calcification was more often seen in seminomas than in non-seminomas.
 CONCLUSIONS: The English testicular cancer patients had a statistically significantly higher TML prevalence than the Danish patients. This observation questions the hypothesised biological association between TML and testicular 
cancer.FUNDING: The Region of Southern Denmark supported this study.TRIAL REGISTRATION: not relevant.

AB - INTRODUCTION: Testicular cancer is the most common type of cancer in young Caucasian men. It has been suggested that testicular microlithiasis (TML) is a premalignant condition. This study's objective was to investigate TML histology prevalence in testicular cancer patients in two European populations.METHODS: We analysed archived histopathology orchiectomy specimens from 152 patients diagnosed with testicular cancer at Fredericia Hospital in Denmark from 2004 to 2014, and 106 patients diagnosed at St Thomas' Hospital in London from 2011 to 2015.RESULTS: The Danish patients' median age was 37 years (range: 16-74 years) and the English patients' 36 years (range: 18-78 years). In the Danish patients, 29 (19.1%) had TML, and in the English patients, 43 (40.6%) had TML (p < 0.001). Haematoxylin bodies were slightly more common in the English patients. Laminated calcification was more often seen in seminomas than in non-seminomas.
 CONCLUSIONS: The English testicular cancer patients had a statistically significantly higher TML prevalence than the Danish patients. This observation questions the hypothesised biological association between TML and testicular 
cancer.FUNDING: The Region of Southern Denmark supported this study.TRIAL REGISTRATION: not relevant.

M3 - Journal article

VL - 65

JO - Danish Medical Bulletin (Online)

JF - Danish Medical Bulletin (Online)

SN - 1603-9629

IS - 3

ER -