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Peter Vedsted
General practice preventive health care in non-obstructive coronary artery disease determined by coronary computed tomography angiography
Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review
DOI
- https://doi.org/10.1016/j.ijcard.2018.09.094
Forlagets udgivne version
- Rikke Elmose Mols
- Bjarne Linde Nørgaard ,
- Peter Vedsted
- Dora Körmendiné Farkas
- Hans Erik Bøtker
- Jesper Møller Jensen
Background: The aim of this study was to compare changes in health service utilization, preventive medical management, and cholesterol levels in patients without coronary artery disease (CAD) or with non-obstructive CAD as determined by coronary computed tomography angiography (CTA). Methods: Single-center five-year observational registry-based cohort study of consecutive patients with chest pain undergoing coronary CTA with subsequent 12 months follow-up in general practice. Results: We included 3032 patients with a normal test result (n = 2179) or a diagnosis of non-obstructive CAD (n = 853) by coronary CTA. Median age was 55 (interquartile range: 47–63) years and 44% were males. After coronary CTA, the probability of a decrease in consultations with general practitioner was higher in patients with no CAD compared to patients with non-obstructive CAD (adjusted OR = 0.81 [95% CI: 0.68–0.96], P = 0.016). Accordingly, patients with non-obstructive CAD more frequently received prescriptions on lipid-lowering medical therapy (adjusted OR = 4.50 [95% CI: 3.31–6.12], P < 0.001) than patients with no CAD after coronary CTA. In patients with non-obstructive CAD, mean total-cholesterol reduction was 0.51 (P < 0.001) compared to 0.13 mmol/L (P < 0.001) in patients without non-obstructive CAD. The relative reduction in low-density lipoprotein was 14% higher (P < 0.001) in patients with compared to patients without non-obstructive CAD after coronary CTA. Conclusions: Coronary CTA with subsequent follow-up in general practice has the potential to align health service utilization that prioritizes high-risk patients and facilitate optimized preventive management.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | International Journal of Cardiology |
| Vol/bind | 278 |
| Sider (fra-til) | 14-21 |
| Antal sider | 8 |
| ISSN | 0167-5273 |
| DOI | |
| Status | Udgivet - 1 mar. 2019 |
Se relationer på Aarhus Universitet Citationsformater
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