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Peter Vedsted

Comparison of Tissue Stiffness Using Shear Wave Elastography in Men with Normal Testicular Tissue, Testicular Microlithiasis and Testicular Cancer

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

DOI

  • Malene Roland Pedersen, Department of Radiology, Clinical Cancer Centre, Vejle Hospital - Part of Lillebaelt Hospital, Vejle, Denmark., Urological Research Centre, Vejle Hospital, Part of Lillebaelt Hospital, Vejle, Denmark., Institut for Regional Sundhedsforskning, Syddansk Universitet
  • ,
  • Henrik Møller
  • Palle Jørn Sloth Osther, Urological Research Center, Lillebaelt Hospital, University of Southern Denmark, Institut for Regional Sundhedsforskning, Syddansk Universitet
  • ,
  • Peter Vedsted
  • René Holst, Oslo Centre for Biostatistics and Epidemiology, Department of Biostatistics, Institute of Basic Medical Sciences, University of Oslo, Norway., Institut for Regional Sundhedsforskning, Syddansk Universitet
  • ,
  • Søren Rafael Rafaelsen, Institut for Regional Sundhedsforskning, Syddansk Universitet, Department of Radiology, Clinical Cancer Centre, Vejle Hospital - Part of Lillebaelt Hospital, Vejle, Denmark.

Objectives: To compare elastography measurements in men with normal testicular tissue, testicular microlithiasis and testicular cancer.

Methods: A total of 248 consecutive patients were included. All men provided written informed consent. Testicular stiffness was assessed using shear wave elastography (SWE). Three SWE velocity measurements were assessed in each testicle. The patients were divided into three groups; men with normal testicular tissue (n=130), men with testicular microlithiasis (n=99) and men with testicular cancer (n=19).

Results: We found a higher mean velocity in the group of patients with testicular cancer (1.92 m/s (95% CI 1.82-2.03)) compared to both the group with normal tissue (0.76 m/s (95% CI: 0.75-0.78)) (p<0.001) and the group with testicular microlithiasis 0.79 m/s (95% CI: 0.77-0.81) (p<0.001).

Conclusion: The presence of testicular microlithiasis increased stiffness slightly, but within the range of variation in normal testicles. Increased stiffness may indicate testicular malignancy in testicular lesions. Ultrasound elastography could be a very useful tool when investigating scrotum.

OriginalsprogEngelsk
TidsskriftUltrasound International Open
Vol/bind3
Nummer4
Sider (fra-til)E150-E155
ISSN2199-7152
DOI
StatusUdgivet - 20 dec. 2017

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