Aarhus University Seal / Aarhus Universitets segl

Peter Sørensen

Gene-based Association Approach Identify Genes Across Stress Traits in Fruit Flies

Publikation: KonferencebidragPaperForskningpeer review

Standard

Gene-based Association Approach Identify Genes Across Stress Traits in Fruit Flies. / Rohde, Palle Duun; Edwards, Stefan McKinnon; Sarup, Pernille Merete; Sørensen, Peter.

2014. Paper præsenteret ved 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada.

Publikation: KonferencebidragPaperForskningpeer review

Harvard

Rohde, PD, Edwards, SM, Sarup, PM & Sørensen, P 2014, 'Gene-based Association Approach Identify Genes Across Stress Traits in Fruit Flies', Paper fremlagt ved 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada, 17/08/2014 - 22/08/2014. <https://asas.org/docs/default-source/wcgalp-posters/673_paper_9223_manuscript_493_0.pdf>

APA

Rohde, P. D., Edwards, S. M., Sarup, P. M., & Sørensen, P. (2014). Gene-based Association Approach Identify Genes Across Stress Traits in Fruit Flies. Paper præsenteret ved 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada. https://asas.org/docs/default-source/wcgalp-posters/673_paper_9223_manuscript_493_0.pdf

CBE

Rohde PD, Edwards SM, Sarup PM, Sørensen P. 2014. Gene-based Association Approach Identify Genes Across Stress Traits in Fruit Flies. Paper præsenteret ved 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada.

MLA

Rohde, Palle Duun o.a.. Gene-based Association Approach Identify Genes Across Stress Traits in Fruit Flies. 10th World Congress on Genetics Applied to Livestock Production (WCGALP), 17 aug. 2014, Vancouver, Canada, Paper, 2014. 3 s.

Vancouver

Rohde PD, Edwards SM, Sarup PM, Sørensen P. Gene-based Association Approach Identify Genes Across Stress Traits in Fruit Flies. 2014. Paper præsenteret ved 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada.

Author

Rohde, Palle Duun ; Edwards, Stefan McKinnon ; Sarup, Pernille Merete ; Sørensen, Peter. / Gene-based Association Approach Identify Genes Across Stress Traits in Fruit Flies. Paper præsenteret ved 10th World Congress on Genetics Applied to Livestock Production (WCGALP), Vancouver, Canada.3 s.

Bibtex

@conference{7f480a21018b415ab7d5b2c54ba60161,
title = "Gene-based Association Approach Identify Genes Across Stress Traits in Fruit Flies",
abstract = "Identification of genes explaining variation in quantitative traits or genetic risk factors of human diseases requires both good phenotypic- and genotypic data, but also efficient statistical methods. Genome-wide association studies may reveal association between phenotypic variation and variation at nucleotide level, thus potentially identify genetic variants. However, testing million of polymorphic nucleotide positions requires conservative correction for multiple testing which lowers the probability of finding genes with small to moderate effects. To alleviate this, we apply a gene based association approach grouping variants accordingly to gene position, thus lowering the number of statistical tests performed and increasing the probability of identifying genes with small to moderate effects. Using this approach we identify numerous genes associated with different types of stresses in Drosophila melanogaster, but also identify common genes that affects the stress traits.",
author = "Rohde, {Palle Duun} and Edwards, {Stefan McKinnon} and Sarup, {Pernille Merete} and Peter S{\o}rensen",
year = "2014",
month = aug,
day = "18",
language = "English",
note = "10th World Congress on Genetics Applied to Livestock Production (WCGALP), WCGALP ; Conference date: 17-08-2014 Through 22-08-2014",

}

RIS

TY - CONF

T1 - Gene-based Association Approach Identify Genes Across Stress Traits in Fruit Flies

AU - Rohde, Palle Duun

AU - Edwards, Stefan McKinnon

AU - Sarup, Pernille Merete

AU - Sørensen, Peter

N1 - Conference code: 10th

PY - 2014/8/18

Y1 - 2014/8/18

N2 - Identification of genes explaining variation in quantitative traits or genetic risk factors of human diseases requires both good phenotypic- and genotypic data, but also efficient statistical methods. Genome-wide association studies may reveal association between phenotypic variation and variation at nucleotide level, thus potentially identify genetic variants. However, testing million of polymorphic nucleotide positions requires conservative correction for multiple testing which lowers the probability of finding genes with small to moderate effects. To alleviate this, we apply a gene based association approach grouping variants accordingly to gene position, thus lowering the number of statistical tests performed and increasing the probability of identifying genes with small to moderate effects. Using this approach we identify numerous genes associated with different types of stresses in Drosophila melanogaster, but also identify common genes that affects the stress traits.

AB - Identification of genes explaining variation in quantitative traits or genetic risk factors of human diseases requires both good phenotypic- and genotypic data, but also efficient statistical methods. Genome-wide association studies may reveal association between phenotypic variation and variation at nucleotide level, thus potentially identify genetic variants. However, testing million of polymorphic nucleotide positions requires conservative correction for multiple testing which lowers the probability of finding genes with small to moderate effects. To alleviate this, we apply a gene based association approach grouping variants accordingly to gene position, thus lowering the number of statistical tests performed and increasing the probability of identifying genes with small to moderate effects. Using this approach we identify numerous genes associated with different types of stresses in Drosophila melanogaster, but also identify common genes that affects the stress traits.

M3 - Paper

T2 - 10th World Congress on Genetics Applied to Livestock Production (WCGALP)

Y2 - 17 August 2014 through 22 August 2014

ER -