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Peter Sørensen

Gene set analysis of the EADGENE chicken data-set

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Dokumenter

DOI

  • Biostatistik
  • Molekylær Genetik og Systembiologi
  • Institut for Genetik og Bioteknologi

Background: Gene set analysis is considered to be a way of improving our biological
interpretation of the observed expression patterns. This paper describes different methods applied
to analyse expression data from a chicken DNA microarray dataset.

Results: Applying different gene set analyses to the chicken expression data led to different ranking
of the Gene Ontology terms tested. A method for prediction of possible annotations was applied.

Conclusion: Biological interpretation based on gene set analyses dependent on the statistical
method used. Methods for predicting the possible annotations for genes with unknown function
from the expression data at hand could be useful, but our results indicate that careful validation of
the predictions is needed.

OriginalsprogEngelsk
TidsskriftBMC Proceedings
Nummer4:S8
Antal sider6
ISSN1753-6561
DOI
StatusUdgivet - 2009
BegivenhedEADGENE and SABRE Post-analyses Workshop - Lelystad, Holland
Varighed: 12 nov. 200814 nov. 2008

Konference

KonferenceEADGENE and SABRE Post-analyses Workshop
LandHolland
ByLelystad
Periode12/11/200814/11/2008

Bibliografisk note

Udgivelsesdato: 16. July
Volumne: 3

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