Aarhus Universitets segl

Pernille Tine Jensen

Longitudinal study of uro-gynecological morbidity and quality of life after radical hysterectomy

Publikation: KonferencebidragPosterForskningpeer review

Background: Radical hysterectomy (RH) and pelvic lymphadenectomy is widely used as the primary treatment for lymph node negative early stage cervical cancer. Little knowledge exists concerning the impact of RH on self-assessed urological and gynecological adverse effects as well as the impact of RH on the patients’ level of functioning.
Methods: 173 lymph node-negative, early stage cervical cancer patients who had undergone RH and pelvic lymphadenectomy alone, were assessed prospectively using validated self-assessment questionnaires at 5 weeks and 3, 6, 12, 18, and 24 months after RH. Results were compared with scores from an age-matched control group from the general population.
Results: Compared with the control group, patients reported long-term pain and urological adverse effects: frequent voiding, bladder insensitivity for micturition, and burning sensation or pain during micturition for 6 to 12 months post-surgery, whereas urine retention problems and pain in the pelvic area were reported throughout the first 24 months post-surgery. Temporary (up to 3 months post-surgery) adverse effects were also reported: fatigue, sleep disturbances, constipation, appetite loss, impaired physical, emotional, cognitive, role, and social functioning, and impaired global health status/quality of life. Comparison with an age-matched control group proved useful as it elucidated the prevalence of symptomatology and level of functioning in the general population and thus prevented over-interpretation of the level of problems attributable to the surgery.
Conclusion: RH for early stage cervical cancer is associated with both short and long term urological and pain symptomatology besides having a short-term negative impact on many aspects of the patients’ level of functioning. The latter suggests that, over time, patients adapt well to the morbidity after RH.
StatusUdgivet - 2004
Eksternt udgivetJa
Begivenhed34th congress of NFOG - Helsinki, Finland
Varighed: 12 jun. 200415 jun. 2004


Konference34th congress of NFOG

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