Pernille Tine Jensen

Early-stage cervical carcinoma, radical hysterectomy, and sexual function. A longitudinal study

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Early-stage cervical carcinoma, radical hysterectomy, and sexual function. A longitudinal study. / Jensen, Pernille T; Groenvold, Mogens; Klee, Marianne C; Thranov, Ingrid; Petersen, Morten Aa; Machin, David.

I: Cancer, Bind 100, Nr. 1, 01.01.2004, s. 97-106.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Jensen, PT, Groenvold, M, Klee, MC, Thranov, I, Petersen, MA & Machin, D 2004, 'Early-stage cervical carcinoma, radical hysterectomy, and sexual function. A longitudinal study', Cancer, bind 100, nr. 1, s. 97-106. https://doi.org/10.1002/cncr.11877

APA

Jensen, P. T., Groenvold, M., Klee, M. C., Thranov, I., Petersen, M. A., & Machin, D. (2004). Early-stage cervical carcinoma, radical hysterectomy, and sexual function. A longitudinal study. Cancer, 100(1), 97-106. https://doi.org/10.1002/cncr.11877

CBE

MLA

Vancouver

Jensen PT, Groenvold M, Klee MC, Thranov I, Petersen MA, Machin D. Early-stage cervical carcinoma, radical hysterectomy, and sexual function. A longitudinal study. Cancer. 2004 jan 1;100(1):97-106. https://doi.org/10.1002/cncr.11877

Author

Jensen, Pernille T ; Groenvold, Mogens ; Klee, Marianne C ; Thranov, Ingrid ; Petersen, Morten Aa ; Machin, David. / Early-stage cervical carcinoma, radical hysterectomy, and sexual function. A longitudinal study. I: Cancer. 2004 ; Bind 100, Nr. 1. s. 97-106.

Bibtex

@article{691a82547eb14b9b8d24f6d189dcb525,
title = "Early-stage cervical carcinoma, radical hysterectomy, and sexual function. A longitudinal study",
abstract = "BACKGROUND: Limited knowledge exists concerning the impact of radical hysterectomy (RH) alone on the sexual function of patients with early-stage cervical carcinoma. The authors investigated the longitudinal course of self-reported sexual function after RH.METHODS: The current study was comprised of 173 patients with lymph node-negative, early-stage cervical carcinoma who had undergone RH and pelvic lymphadenectomy. They were assessed prospectively using a validated self-assessment questionnaire 5 weeks and 3 months, 6 months, 12 months, 18 months, and 24 months after RH. Results were compared with an age-matched control group from the general population.RESULTS: Compared with control women, patients experienced severe orgasmic problems and uncomfortable sexual intercourse due to a reduced vaginal size during the first 6 months after RH, severe dyspareunia during the first 3 months, and sexual dissatisfaction during the 5 weeks after RH. A persistent lack of sexual interest and lubrication were reported throughout the first 2 years after RH. Long-term lack of sexual interest and insufficient vaginal lubrication were confirmed by the patient's self-reported changes 12 months after RH compared with before the cancer diagnosis and by a pre-post comparison within patients. However, most of the patients who were sexually active before their cancer diagnosis were sexually active again 12 months after surgery (91%), although with a decrease in sexual frequency reported.CONCLUSIONS: RH had a persistent and negative impact on patients' sexual interest and vaginal lubrication whereas the majority of other sexual and vaginal problems disappeared over time. Sexual and vaginal problems in the short-term and long-term after RH should be discussed with the patient before and after surgery.",
keywords = "Adult, Aged, Carcinoma/pathology, Case-Control Studies, Female, Humans, Hysterectomy/adverse effects, Longitudinal Studies, Lymph Node Excision, Middle Aged, Neoplasm Staging, Patient Satisfaction, Sexual Dysfunction, Physiological/etiology, Uterine Cervical Neoplasms/pathology, Vagina/physiology",
author = "Jensen, {Pernille T} and Mogens Groenvold and Klee, {Marianne C} and Ingrid Thranov and Petersen, {Morten Aa} and David Machin",
note = "Copyright 2003 American Cancer Society.",
year = "2004",
month = jan,
day = "1",
doi = "10.1002/cncr.11877",
language = "English",
volume = "100",
pages = "97--106",
journal = "Cancer",
issn = "0008-543X",
publisher = "JohnWiley & Sons, Inc.",
number = "1",

}

RIS

TY - JOUR

T1 - Early-stage cervical carcinoma, radical hysterectomy, and sexual function. A longitudinal study

AU - Jensen, Pernille T

AU - Groenvold, Mogens

AU - Klee, Marianne C

AU - Thranov, Ingrid

AU - Petersen, Morten Aa

AU - Machin, David

N1 - Copyright 2003 American Cancer Society.

PY - 2004/1/1

Y1 - 2004/1/1

N2 - BACKGROUND: Limited knowledge exists concerning the impact of radical hysterectomy (RH) alone on the sexual function of patients with early-stage cervical carcinoma. The authors investigated the longitudinal course of self-reported sexual function after RH.METHODS: The current study was comprised of 173 patients with lymph node-negative, early-stage cervical carcinoma who had undergone RH and pelvic lymphadenectomy. They were assessed prospectively using a validated self-assessment questionnaire 5 weeks and 3 months, 6 months, 12 months, 18 months, and 24 months after RH. Results were compared with an age-matched control group from the general population.RESULTS: Compared with control women, patients experienced severe orgasmic problems and uncomfortable sexual intercourse due to a reduced vaginal size during the first 6 months after RH, severe dyspareunia during the first 3 months, and sexual dissatisfaction during the 5 weeks after RH. A persistent lack of sexual interest and lubrication were reported throughout the first 2 years after RH. Long-term lack of sexual interest and insufficient vaginal lubrication were confirmed by the patient's self-reported changes 12 months after RH compared with before the cancer diagnosis and by a pre-post comparison within patients. However, most of the patients who were sexually active before their cancer diagnosis were sexually active again 12 months after surgery (91%), although with a decrease in sexual frequency reported.CONCLUSIONS: RH had a persistent and negative impact on patients' sexual interest and vaginal lubrication whereas the majority of other sexual and vaginal problems disappeared over time. Sexual and vaginal problems in the short-term and long-term after RH should be discussed with the patient before and after surgery.

AB - BACKGROUND: Limited knowledge exists concerning the impact of radical hysterectomy (RH) alone on the sexual function of patients with early-stage cervical carcinoma. The authors investigated the longitudinal course of self-reported sexual function after RH.METHODS: The current study was comprised of 173 patients with lymph node-negative, early-stage cervical carcinoma who had undergone RH and pelvic lymphadenectomy. They were assessed prospectively using a validated self-assessment questionnaire 5 weeks and 3 months, 6 months, 12 months, 18 months, and 24 months after RH. Results were compared with an age-matched control group from the general population.RESULTS: Compared with control women, patients experienced severe orgasmic problems and uncomfortable sexual intercourse due to a reduced vaginal size during the first 6 months after RH, severe dyspareunia during the first 3 months, and sexual dissatisfaction during the 5 weeks after RH. A persistent lack of sexual interest and lubrication were reported throughout the first 2 years after RH. Long-term lack of sexual interest and insufficient vaginal lubrication were confirmed by the patient's self-reported changes 12 months after RH compared with before the cancer diagnosis and by a pre-post comparison within patients. However, most of the patients who were sexually active before their cancer diagnosis were sexually active again 12 months after surgery (91%), although with a decrease in sexual frequency reported.CONCLUSIONS: RH had a persistent and negative impact on patients' sexual interest and vaginal lubrication whereas the majority of other sexual and vaginal problems disappeared over time. Sexual and vaginal problems in the short-term and long-term after RH should be discussed with the patient before and after surgery.

KW - Adult

KW - Aged

KW - Carcinoma/pathology

KW - Case-Control Studies

KW - Female

KW - Humans

KW - Hysterectomy/adverse effects

KW - Longitudinal Studies

KW - Lymph Node Excision

KW - Middle Aged

KW - Neoplasm Staging

KW - Patient Satisfaction

KW - Sexual Dysfunction, Physiological/etiology

KW - Uterine Cervical Neoplasms/pathology

KW - Vagina/physiology

U2 - 10.1002/cncr.11877

DO - 10.1002/cncr.11877

M3 - Journal article

C2 - 14692029

VL - 100

SP - 97

EP - 106

JO - Cancer

JF - Cancer

SN - 0008-543X

IS - 1

ER -