Per Hove Thomsen

Predictors associated with improved cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Standard

Predictors associated with improved cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder. / Torp, Nor Christian; Dahl, Kitty; Skarphedinsson, Gudmundur; Compton, Scott; Thomsen, Per Hove; Weidle, Bernhard; Hybel, Katja Anna; Valderhaug, Robert; Melin, Karin; Nissen, Judith Becker; Ivarsson, Tord.

I: American Academy of Child and Adolescent Psychiatry. Journal, Bind 54, Nr. 3, 03.2015, s. 200-207.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Torp, NC, Dahl, K, Skarphedinsson, G, Compton, S, Thomsen, PH, Weidle, B, Hybel, KA, Valderhaug, R, Melin, K, Nissen, JB & Ivarsson, T 2015, 'Predictors associated with improved cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder', American Academy of Child and Adolescent Psychiatry. Journal, bind 54, nr. 3, s. 200-207. https://doi.org/10.1016/j.jaac.2014.12.007

APA

Torp, N. C., Dahl, K., Skarphedinsson, G., Compton, S., Thomsen, P. H., Weidle, B., Hybel, K. A., Valderhaug, R., Melin, K., Nissen, J. B., & Ivarsson, T. (2015). Predictors associated with improved cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder. American Academy of Child and Adolescent Psychiatry. Journal, 54(3), 200-207. https://doi.org/10.1016/j.jaac.2014.12.007

CBE

Torp NC, Dahl K, Skarphedinsson G, Compton S, Thomsen PH, Weidle B, Hybel KA, Valderhaug R, Melin K, Nissen JB, Ivarsson T. 2015. Predictors associated with improved cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder. American Academy of Child and Adolescent Psychiatry. Journal. 54(3):200-207. https://doi.org/10.1016/j.jaac.2014.12.007

MLA

Torp, Nor Christian o.a.. "Predictors associated with improved cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder". American Academy of Child and Adolescent Psychiatry. Journal. 2015, 54(3). 200-207. https://doi.org/10.1016/j.jaac.2014.12.007

Vancouver

Torp NC, Dahl K, Skarphedinsson G, Compton S, Thomsen PH, Weidle B o.a. Predictors associated with improved cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder. American Academy of Child and Adolescent Psychiatry. Journal. 2015 mar;54(3):200-207. https://doi.org/10.1016/j.jaac.2014.12.007

Author

Torp, Nor Christian ; Dahl, Kitty ; Skarphedinsson, Gudmundur ; Compton, Scott ; Thomsen, Per Hove ; Weidle, Bernhard ; Hybel, Katja Anna ; Valderhaug, Robert ; Melin, Karin ; Nissen, Judith Becker ; Ivarsson, Tord. / Predictors associated with improved cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder. I: American Academy of Child and Adolescent Psychiatry. Journal. 2015 ; Bind 54, Nr. 3. s. 200-207.

Bibtex

@article{b831c65d04814ac5819d71568709a7a4,
title = "Predictors associated with improved cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder",
abstract = "OBJECTIVE: To identify predictors of treatment response in a large sample of pediatric participants with obsessive-compulsive disorder (OCD). The Nordic Long-term Obsessive compulsive disorder (OCD) Treatment Study (NordLOTS) included 269 children and adolescents, 7 to 17 years of age, with a DSM-IV diagnosis of OCD. Outcomes were evaluated after 14 weekly sessions of exposure-based cognitive-behavioral therapy (CBT).METHOD: The association of 20 potential predictors, identified by literature review, along with their outcomes, was evaluated using the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) posttreatment. A CY-BOCS total score of ≤15 was the primary outcome measure.RESULTS: The univariate analyses showed that children and adolescents who were older had more severe OCD, greater functional impairment, higher rates of internalizing and externalizing symptoms, and higher levels of anxiety and depression symptoms before treatment had significantly poorer outcomes after 14 weeks of treatment. However, only age was a significant predictor in the multivariate model.CONCLUSION: In the multivariate analysis, only age predicted better treatment outcome. Using univariate analysis, a variety of predictors of poorer treatment outcome after CBT was identified. The high impact of comorbid symptoms on outcome in pediatric OCD suggests that treatment should address comorbidity issues. The lack of a family predictor may be related to high family involvement in this study. Future research strategies should focus on optimizing intervention in the presence of these characteristics to achieve greater benefits for patients with OCD. Clinical trial registration information-Nordic Long-term Obsessive compulsive disorder (OCD) Treatment Study; www.controlled-trials.com; ISRCTN66385119.",
author = "Torp, {Nor Christian} and Kitty Dahl and Gudmundur Skarphedinsson and Scott Compton and Thomsen, {Per Hove} and Bernhard Weidle and Hybel, {Katja Anna} and Robert Valderhaug and Karin Melin and Nissen, {Judith Becker} and Tord Ivarsson",
note = "Copyright {\textcopyright} 2015 American Academy of Child & Adolescent Psychaitry. Published by Elsevier Inc. All rights reserved.",
year = "2015",
month = mar,
doi = "10.1016/j.jaac.2014.12.007",
language = "English",
volume = "54",
pages = "200--207",
journal = "American Academy of Child and Adolescent Psychiatry. Journal",
issn = "0890-8567",
publisher = "Elsevier BV",
number = "3",

}

RIS

TY - JOUR

T1 - Predictors associated with improved cognitive-behavioral therapy outcome in pediatric obsessive-compulsive disorder

AU - Torp, Nor Christian

AU - Dahl, Kitty

AU - Skarphedinsson, Gudmundur

AU - Compton, Scott

AU - Thomsen, Per Hove

AU - Weidle, Bernhard

AU - Hybel, Katja Anna

AU - Valderhaug, Robert

AU - Melin, Karin

AU - Nissen, Judith Becker

AU - Ivarsson, Tord

N1 - Copyright © 2015 American Academy of Child & Adolescent Psychaitry. Published by Elsevier Inc. All rights reserved.

PY - 2015/3

Y1 - 2015/3

N2 - OBJECTIVE: To identify predictors of treatment response in a large sample of pediatric participants with obsessive-compulsive disorder (OCD). The Nordic Long-term Obsessive compulsive disorder (OCD) Treatment Study (NordLOTS) included 269 children and adolescents, 7 to 17 years of age, with a DSM-IV diagnosis of OCD. Outcomes were evaluated after 14 weekly sessions of exposure-based cognitive-behavioral therapy (CBT).METHOD: The association of 20 potential predictors, identified by literature review, along with their outcomes, was evaluated using the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) posttreatment. A CY-BOCS total score of ≤15 was the primary outcome measure.RESULTS: The univariate analyses showed that children and adolescents who were older had more severe OCD, greater functional impairment, higher rates of internalizing and externalizing symptoms, and higher levels of anxiety and depression symptoms before treatment had significantly poorer outcomes after 14 weeks of treatment. However, only age was a significant predictor in the multivariate model.CONCLUSION: In the multivariate analysis, only age predicted better treatment outcome. Using univariate analysis, a variety of predictors of poorer treatment outcome after CBT was identified. The high impact of comorbid symptoms on outcome in pediatric OCD suggests that treatment should address comorbidity issues. The lack of a family predictor may be related to high family involvement in this study. Future research strategies should focus on optimizing intervention in the presence of these characteristics to achieve greater benefits for patients with OCD. Clinical trial registration information-Nordic Long-term Obsessive compulsive disorder (OCD) Treatment Study; www.controlled-trials.com; ISRCTN66385119.

AB - OBJECTIVE: To identify predictors of treatment response in a large sample of pediatric participants with obsessive-compulsive disorder (OCD). The Nordic Long-term Obsessive compulsive disorder (OCD) Treatment Study (NordLOTS) included 269 children and adolescents, 7 to 17 years of age, with a DSM-IV diagnosis of OCD. Outcomes were evaluated after 14 weekly sessions of exposure-based cognitive-behavioral therapy (CBT).METHOD: The association of 20 potential predictors, identified by literature review, along with their outcomes, was evaluated using the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) posttreatment. A CY-BOCS total score of ≤15 was the primary outcome measure.RESULTS: The univariate analyses showed that children and adolescents who were older had more severe OCD, greater functional impairment, higher rates of internalizing and externalizing symptoms, and higher levels of anxiety and depression symptoms before treatment had significantly poorer outcomes after 14 weeks of treatment. However, only age was a significant predictor in the multivariate model.CONCLUSION: In the multivariate analysis, only age predicted better treatment outcome. Using univariate analysis, a variety of predictors of poorer treatment outcome after CBT was identified. The high impact of comorbid symptoms on outcome in pediatric OCD suggests that treatment should address comorbidity issues. The lack of a family predictor may be related to high family involvement in this study. Future research strategies should focus on optimizing intervention in the presence of these characteristics to achieve greater benefits for patients with OCD. Clinical trial registration information-Nordic Long-term Obsessive compulsive disorder (OCD) Treatment Study; www.controlled-trials.com; ISRCTN66385119.

U2 - 10.1016/j.jaac.2014.12.007

DO - 10.1016/j.jaac.2014.12.007

M3 - Journal article

C2 - 25721185

VL - 54

SP - 200

EP - 207

JO - American Academy of Child and Adolescent Psychiatry. Journal

JF - American Academy of Child and Adolescent Psychiatry. Journal

SN - 0890-8567

IS - 3

ER -