Per Hove Thomsen

One-Year Outcome for Responders of Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review


  • Davíð R.M.A. Højgaard
  • Katja A. Hybel
  • Tord Ivarsson, Center for Child and Adolescent Mental Health
  • ,
  • Gudmundur Skarphedinsson, University of Iceland
  • ,
  • Judith Becker Nissen
  • Bernhard Weidle, Norges teknisk-naturvitenskapelige universitet, Trondheim
  • ,
  • Karin Melin, Queen Silvia Children's Hospital
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  • Nor Christian Torp, Vestre Viken Hospital Trust
  • ,
  • Robert Valderhaug, Norges teknisk-naturvitenskapelige universitet, Trondheim, Hospital of Aalesund
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  • Kitty Dahl, Center for Child and Adolescent Mental Health
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  • Erik Lykke Mortensen, Center for Healthy Aging, Københavns Universitet
  • ,
  • Scott Compton, Duke University Medical Center
  • ,
  • Sanne Jensen
  • Fabian Lenhard, Karolinska Institutet
  • ,
  • Per Hove Thomsen

Objective This study describes 1-year treatment outcomes from a large sample of cognitive-behavioral therapy (CBT) responders, investigates age as a possible moderator of these treatment outcomes, and evaluates clinical relapse at the 1-year follow-up. Method This study is the planned follow-up to the Nordic Long-term OCD [obsessive-compulsive disorder] Treatment Study (NordLOTS), which included 177 children and adolescents who were rated as treatment responders following CBT for OCD. Participants were assessed with the Children's Yale−Brown Obsessive-Compulsive Scale (CY-BOCS) at 6- and 12-month follow-up. Treatment response and remission were defined as CY-BOCS total scores ≤15 and ≤10, respectively. Linear mixed-effects models were used to analyze all outcomes. Results At 1 year, a total of 155 children and adolescents (87.6%) were available for follow-up assessment, with 142 of these (91.6%) rated below a total score of ≤15 on the CY-BOCS. At 1-year follow-up, 121 (78.1%) were in remission. On average, CY-BOCS total scores dropped by 1.72 points during the first year after terminating treatment (p =.001). A total of 28 participants (15.8%) relapsed (CY-BOCS ≥ 16) at either the 6- or 12-month assessment; only 2 patients required additional CBT. Conclusion Results suggest that manualized CBT in a community setting for pediatric OCD has durable effects for those who respond to an initial course of treatment; children and adolescents who respond to such treatment can be expected to maintain their treatment gains for at least 1 year following acute care. Clinical trial registration information– Nordic Long-term Obsessive-Compulsive Disorder (OCD) Treatment Study;; ISRCTN66385119.

TidsskriftJournal of the American Academy of Child and Adolescent Psychiatry
Sider (fra-til)940-947.e1
StatusUdgivet - 1 nov. 2017

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