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Per Bendix Jeppesen

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Curriculum Vitae

                                 CURRICULUM VITAE           

 

 Name: Per Bendix Jeppesen             Nationality: Danish

 

The Faculty of Health Sciences, Aarhus University, Department of Clinical Medicine ,  Aarhus University Hospital, Diabetes and Hormone Diseases -  Medical Research Laboratory, Building J – level 1, J103-185, Palle Juul-Jensens Boulevard 165, 8200 Aarhus N, Denmark

Telephone:  + 45 28151877

e-mail:         per.bendix.jeppesen@clin.au.dk

Home address: Aaskraenten 10, DK-8250 Egaa, Denmark

Home Telephone: +45 28151877

Date of birth: 260566

 

Professional qualifications:

Cand. Scient (M. Sc.), Aarhus University 1997. Master thesis. Title: “The effect of the diterpene glucoside stevioside and the aglucon steviol, on the endocrine pancreas”

Research Fellow, The Faculty of Health Sciences, Aarhus University, Department of Endocrinology and Metabolism C, Tage-Hansens Gade 2, DK-8000 Aarhus C, Denmark 1998.

Ph.D degree in Medicine: The Faculty of Health Sciences, Aarhus University. Title of the Ph.D-thesis: “The diterpene glycoside, stevioside, a potential useful drug in the treatment of type 2 diabetes and the metabolic syndrome, 2002.

Assistant Professor, The Faculty of Health Sciences, Aarhus University,  Department of Endocrinology and Metabolism C, Tage-Hansens Gade 2, DK-8000 Aarhus C, Denmark , 2002.

Associate Professor, The Faculty of Health Sciences, Aarhus University , Department of Endocrinology and Metabolism C, Tage-Hansens Gade 2, DK-8000 Aarhus C, Denmark , 2005-

 

Member of the steering committee of The Latin American Center, University of Aarhus (LACUA)  from nov.2007.

Honorary member of the European Stevia Association (EUSTAS), Full Voting member, since 2009.

Board member of the Diabetes and Nutrition Study Group (DNSG) of the European Association for the study of Diabetes (EASD) since 2010.

Member at the Editorial Board of the International Journal: The Review of Diabetic Studies since Dec. 2007-2012 and Nutrients since 2020.

Clinical project leader for the MAXVEG project (FØSU 2009)

Member of the Education Committee and working group (MEF) for Molecular Nutrition and Food Technology, Science.

Member of Aarhus University, AU Research and Talent for Health, to initiate research collaboration between Danish and Brazilian Universities established 2013.

Plan manager of the animal stables on Diabetes and Hormone Diseases -  Medical Research Laboratory, Aarhus University Hospital, Skejby. 2014.

Clinical leader for the Red Clover study 2013

Clinical project leader for the Green kale project 2017

Clinical project leader for the Innosweet Project. 2017(6150-00037A).

Clinical project leader GUDP (34009-17-1274) ”ProBioWheatgrass, 2017

Visiting Professor at Guangdong pharmaceutical University, Guangzhou, China, 2019-

Scientific adviser and collaborator: Sierra Maestra project, Ministry of Health, Cuba. 2019-

 

 

 

 

Research experience abroad:

The Faculty of Pharmaceutical, Federal University of Bahia, Brazil, 1991-92. Pre-Master Thesis. Title: “General fytokemisk analyse og kromosom undersøgelse af medicinalplanten Stevia rebaudiana Bertoni”

The Faculty of Pharmaceutical, University of Caracas, Venezuela, 1997.

The Faculty of Pharmaceutical, Federal University of Bahia, Brazil, 1997.

Department of Laboratory Medicine, Ehime University School of Medicine, Japan, 1998-99.

Head Diabetes Unit, National University of Asuncion, Paraguay, 2000

Head Diabetes Unit, National University of Asuncion, Paraguay, 2002

Clinical Management Leader for the Danish-Paraguayan Stevia study on type 2 diabetic patients. Supported and financed by DANIDA (RUF), Denmark. 2003-5.

Guangdong Pharmaceutical University, Guangzhou, China, 2019-

Sierra Maestra project, Ministry of Health, Cuba. 2019-

 

Teaching experience:

 

  • Special courses for dieticians at Aarhus University, subject: “Human physiology” , Denmark, 1999.
  • University of Southern Denmark, Faculty of Biology.  Course: “Natural products in biomedical”2000-2001.
  • Pass the course “ University pedagogic for Assistant Prof. and supervisors” 2004.
  • External Consultant, Co-organiser at Novo Nordisk A/S - Light House Programme 2004.
  • PhD-course, Aarhus University, Faculty of Health Sciences, Organiser and teacher: Title Molecular and Cellular Endocrinology. 2008, 2010 and 2012.
  • Teacher and co-organiser in M.Sci courses “ Bioactive Food Component and Functional Foods”  in the education Molecular Nutrition and Food technology – Aarhus University. Since 2008-
  • Teacher and co-organiser in M.Sci courses “Advanced Molecular Nutrition”  in the education Molecularly Nutrition and Food technology – Aarhus University. Since 2008-
  • Teacher and co-organiser in M.Sci courses “Special Nutrition on”  in the education Molecular Nutrition and Food technology – Aarhus University. Since 2009-
  • Organizer of SYSDIET Symposium (The Nordic Centre of Excellence: System Biology in Dietary Intervention and Cohort Studies), Aarhus University: Use of animal models for pathophysiological and nutrigenomic research, November, 2010.
  • Organizer of Stevia Symposium, Landbo Nord, Vrå Højskole. 2009 and 2010.
  • Organizer of SYSDIET Symposium (The Nordic Centre of Excellence: System Biology in Dietary Intervention and Cohort Studies), Aarhus University: Use of animal models for pathophysiological and nutrigenomic research, November, 2010.
  • Chairman:4th Stevia Symposium  (EUSTAS)- 2010, Leuven, Belgium
  • Chairman:6th Stevia Symposium  (EUSTAS)- 2012, Leuven, Belgium
  • Chairman: 30th International Symposium on Diabetes and Nutrition- June 2012, Athens, Greece.
  • • Organizer of the DNSG Symposium (Diabetes Nutrition Study Group) a part of EASD, at Skagen, Denmark 19-22 June- 2017.

 

 

Scientific reviewer (Selected):

  • Member at the Editorial Board of the International Journal:
  • The Review of Diabetic Studies from Dec. 2007
  • Editor for the journal “Nutrients” since 2020
  • Science Foundation Ireland – Basic Research Grant Programme
  • Journal of Agricultural and Food Chemistry
  • Am. J. Physiol. Endocrinol. Metab.
  • Clinical Chemistry
  • Rev Diabet Stud
  • Journal of Applied Physiology
  • Diabetes, Obesity and Metabolism
  • Evidence-Based Complementary and Alternative Medicine
  • PLoS One.
  • Diabetes
  • European Journal of Clinical Nutrition
  • Journal of Herbal Medicine
  • International Journal of Molecular Sciences
  • International Journal of Environmental Research and Public Health

 

Professional résumé:

Publications, patents, advisory functions and collaboration: PhD-Superviser: Served as primary supervisor or co- supervisor for 17 PhD dissertations 16 defended, and 20 M.Sci. 117 publications out of these 13 patents. More than 150 oral presentations and posters presented at international scientific meetings, symposiums and congresses and 40 popular papers. Scientific reviewer for more than 25 international journals.

Awards:

  1. I) Winner of best poster presentation on the third Ph.D-day, the Faculty of Health Science, University of Aarhus 1998.
  2. II) Winner of 3rd best poster presentation on the forth Ph.D-day, The Faculty of Health Science, University of Aarhus, 2000.

III) Winner of 3rd best poster presentation on the fifth Ph.D-day, The Faculty of Health Sciences, University of Aarhus, 2001.

  1. IV) Award at the Aventis Diabetes og Hjertekar Symposium, 2001, Munkebjerg Hotel, Vejle, DK.
  2. V) Award at the 20th International Symposium on Diabetes and Nutrition, 2002, Samos, Greece.

VI Award best presentation at 2nd World Conference on Sugar & Salt Reduction Strategies 2013, Paris, France 2013.

VII Award. Winner of European Food Venture Forum- 2013, Aarhus Denmark

 

Guest lectures:

 

  • University of Southern Denmark, Faculty of Biology. Subject: Traditional Plant-medicine in the treatment of type 2 diabetes 2000 and 2001
  • The Annual IDDC-meeting .Hotel Normandy, Paris, France. Subject: Stevioside – a potential antidiabetic agent. May 2001.
  • Federation of European Biochemical Societies, Dublin City University, Dublin, Ireland. Subject: Drug discovery. Sept. 2002.
  • Sociedad Paraguaya de Diabetologia , Hotel Excelsior, Asuncion, Paraguay.“ Nuevas alternatives en el tratamiebto de la Diabetes Mellitus Tipo 2” Maj 2003.
  • Katholieke Universiteit Leuven, Faculty of Functional Biology, Belgien: “Stevioside as a potential useful drug in the treatment of type 2 diabetes and the metabolic syndrome", April 2004.
  • Nederlandse Verening voor Fytotherapie, Hotel Oud London, Zeist Holland: “Can stevioside be a new useful drug in the treatment of type 2 diabetes and the metabolic syndrome?”, May 2005.
  • The 1. th International Stevia Meeting, Asuncion, Paraguay “Can stevioside be a new useful drug in the treatment of type 2 diabetes and the metabolic syndrome?”; 17-18 August 2005.
  • The 2nd International Stevia Symposium, November 9-10, Asunción – Paraguay “new aspects of the components of Stevia in type 2 Diabetes”. November 9-10, 2007.
  • The 2nd Stevia symposium of the European Stevia Association , Leuven – Belgian, june 2008 “  Stevia components  improve glucose homeostasis in Type 2 Diabetes? - A new promising drug”
  • VI SIMPOSIO INTERNACIONAL DE KA´A HE’Ë – STEVIA, 13 y 14 de Noviembre de 2012, Asuncion, Paraguay. ” Stevia and its impact on Health Food or Medicine”.
  • Federal University of Rio de Janeiro, Brazil, Faculdade de Medicina, 8 Nov. 2013. “Stevia and its impact on Health”.
  • Federal University of Bahia, Brazil, Faculty of Pharmacy. March 2013.” Stevia and its impact on Health Food or Medicine”.
  • University of São Paolo,  Instituto de Ortopedia e  Traumatologia, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo. Nov. 2013 “.” Stevia and its impact on Health Food or Medicine”.
  • University of São Paolo (USP) – Piracicaba Campus, Department of Agro-food Industry, Food and Nutrition. Nov 2013. “Novel beneficial effect a bioactive compound from plants – Food or Medicine ?”
  • Guangdong Pharmaceutical University, Guangzhou, China, 2019. “The healthy beneficial effects of plant based bioactive compounds”
  • Sierra Maestra project, Ministry of Health, Cuba. 2019.” Stevia and its impact on health Food or Medicine ?”

 

 

Memberships:

European Association of the study of Diabetes (EASD)

Danish Endocrine Society (DES)

European Scientific Cooperative on Phytotherapy

Dansk selskab for Fytoterapi (DAN-Fyt)

Honorary member of the EUSTAS, Full Voting member, 2009

The International Stevia Association (ISA) (Co-founder and board member)

 

 

 

Selected publications:

 

  • Jeppesen P B, Gregersen S, Poulsen C R, Hermansen K. Stevioside acts directly on the pancreatic beta-cell to secrete insulin: Actions independent of cAMP and ATP-sensitive K-channel activity. Metabolism 49(2), pp 208-214, 2000.

 

  • Jeppesen P B, Gregersen S, Alstrup K K, Hermansen K. Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: Studies in the diabetic Goto-Kakizaki (GK) rats. Phytomedicine, Vol. 9(1):9-14, 2002.

 

  • Jeppesen P B, Gregersen S, Rolfsen SED, Jepsen M, Colombo M, Agger A, Xiao J, Kruhøffer M, Ørntoft T and Hermansen K. Anti-hyperglycemic and blood pressure-reducing effects of stevioside in the diabetic Goto-Kakizaki (GK) rat. Metabolism, Mar;52(3):372-8, 2003. 

 

  • Gregersen S, Thomsen JL, Jeppesen PB, Alstrup KK, Brock B, Pedersen SB, Kristensen K, Hermansen K. Impact of dietary FA and energy restriction on plasma leptin and ob gene expression in mice. Lipids, May;38(5):513-7, 2003

 

  • Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism, vol 53, no 1:73-76, 2004.

 

  • Reziwanggu Abudula, Per Bendix Jeppesen, Stig Eric D Rolfsen, Jianzhong Xiao, Kjeld Hermansen Rebaudioside A potently stimulates insulin secretion from isolated mouse islets: Studies on the dose-, glucose- and calcium-dependency. Metabolism Oct ; 53 (10): 1378-81, 2004.

 

  • Hong J, Abudula R, Chen J, Jeppesen P B, Rolfsen S E D, Xiao J, Colombo M, Hermansen K. The short-term effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration, and degree of unsaturation. Studies in vitro. Metabolism, 54(10): 1329-1336, 2005.

 

  • Dyrskog S E U, Jeppesen P B, Colombo M, Abudula R, Hermansen K. Preventive effects of a soy-based diet supplemented with stevioside on development of the metabolic syndrome and type 2 diabetes in Zucker diabetic fatty rats. Metabolism, ; 54(9): 1181-1188, 2005

 

  • Colombo M, Gregersen S, Kruhoeffer M, Agger A, Xiao J, Jeppesen P B, Orntoft T, Ploug T, Galbo H, Hermansen K. Prevention of hyperglycemia in Zucker diabetic fatty rats by exercise training: effects on gene expression in insulin-sensitive tissues determined by high-density oligonucletide macroarray analysis. Metabolism 54: 1571-81, 2005

 

  • Colombo M, Kruhøffer M, Gregersen S,  Agger A, Jeppesen P B,  Ørntof T, Hermansen K. Energy restriction prevents the development of type 2 diabetes in Zucker diabetic fatty rats: coordinated patterns of gene rxpression for energy metabolism in insulin-sensitive tissues and pancreatic islets determined by oligonucleotide microarray analysis. Metabolism, 55: 43-52, 2006

 

  • Dyrskog S E U, Jeppesen P B, Chen J, Christensen L P, and Hermansen K. The diterpene glycoside, Rebaudioside A, does not improve the glycemic control or affect the blood pressure after long-term treatment in the Goto-Kakizaki rat. The Review of Diabetes studies, 2: 84-91, 2005.

 

  • Chen J, Jeppesen P B, Abudula R, Dyrskog S E U, Clombo M, Hermansen K. Stevioside does not cause increased basal insulin secretion or beta-cell desensitization as does the sulphonylurea, glibenclamide: Studies in Vitro. Life Science, 6; 78 (15): 1748-53, 2006

 

  • Hong J, Chen Li, Jeppesen P B, Nordentoft I, Hermansen K. Stevioside counteracts the alpha cell hypersecretion caused by long-term palmitate exposure. Am. J Physiol. Endocrinol Metab. 290(3): 416-22, 2006.

 

  • Chen J, Jeppesen P B, Nordentoft I, Hermansen K. Stevioside counteracts the glyburide-induced desensitization of the pancreatic beta-cell function in mice: Studies in vitro. Metabolism 55: 1675-80, 2006.

 

  1. O´Driscoll L, Gammell P, McKiernan E, Ryan E, Jeppesen P B, Clynes M.  Phenotypic and gene expression changes between low (glucose-responsive) and High (glucose non-responsive) MIN-6 beta cells. J. Endocrinology Dec;191(3):665-76,

 

  • Dowling P, O´Driscoll L, O´Sullivan F, Dowd A, Henry M, Jeppesen PB, Meledy P, Clynes M. Proteomic screening of glucose-responsive and glucose non-responsive MIN-6 beta cells reveals differential expression of proteins involved in protein folding, secretion and oxidative stress. Proteomics Dec;6(24): 6578-87, 2006.

 

  • Chen J, Jeppesen P B, Nordentoft I, Hermansen K. Stevioside Counteracts Beta-Cell Lipotoxicity without Affecting the Acetyl CoA Carboxylase. Rev Diabet Stud. 3:178-188, 

 

  • Jeppesen P B, Rolfsen S E D, Agger A, Gregersen S, Colombo M, Xiao J, Hermansen K. Can stevioside in combination with a soy-based dietary supplement be a new useful treatment of type 2 diabetes? An in vivo study in the diabetic goto-kakizaki rat.. Rev Diabet Stud. 3, 189-199, 2006.

 

  • Hong J, Jeppesen PB, Nordentoft I, Hermansen K: Fatty acid induced effect on glucagon secretion is mediated via fatty acid oxidation. Diabetes/Metabolism Research and Reviews. 23:202-210, 2007.

 

  • Chen J, Jeppesen P B, Nordentoft I, Hermansen K. Stevioside Improves Pancreatic Beta-Cell Function during Glucotoxicity via Regulation of Acetyl-CoA Carboxylase.  J Physiol. Endocrinol Metab, 292 (6): 1906-16, 2007.

 

  • Nordentoft I, Jeppesen P B, Nielsen A L, Jørgensen P, Hermansen K. Expression Analysis of cPLA2 Alpha Interacting TIP60 in Diabetic KKAy and Non-Diabetic C57BL Wild-Type Mice: No Impact of Transient and Stable TIP60 Overexpression on Glucose-Stimulated Insulin Secretion in Pancreatic Beta-Cells. Rev Diabet Stud. 4(3):147-58, 2007

 

  • Nordentoft I, Jeppesen P.B., Hong J., Abudula R., Hermansen K. Isosteviol increases insulin sensitivity and changes gene expression of key insulin regulatory genes and transcription factors in islets of the diabetic KKAy-mouse.  Diabetes, Obesity and Metabolism. 10 (10): 939-49, 2008.

 

  • Abudula R, Matchkov V V, Jeppesen P B, Nilsson H, Aalkjær C, Hermansen K. Rebaudioside A directly stimulates insulin secretion from pancreatic beta cells: a glucose-dependent action via inhibition of ATP-sensitive K+-channels. Diabetes, Obesity and Metabolism. 10 (11): 1074-85, 2008.

 

  • Hong J, Jeppesen P B, Hermansen K. Effects of elevated fatty acids and high glucose levels on pancreatic Diabetes, Obesity and Metabolism 11(4):397-404, 2008

 

  • Nordentoft I, Jeppesen P.B., Hong J., Abudula R., Hermansen K. Increased insulin sensitivity and changes in the expression profile of key insulin regulatory genes and beta cell transcription factors in diabetes KKAY-mice after feeding with a soy bean protein rich diet high in isoflavone content. J. Agric. Foof Chem. 56 (12): 4377-85, 2008.

 

 

  • Dowling P, Shields W, Rani S, Meleady P, Henry M, Jeppesen PB, O'Driscoll L, Clynes M. Proteomic analysis of conditioned media from glucose responsive and glucose non-responsive phenotypes reveals a panel of secreted proteins associated with beta cell dysfunction. Electrophoresis. 2008 Nov;29(20):4141-9.doi: 10.1002/elps.200800152
  • Liu Z, Jeppesen P B, Gregersen S, Chen X, Hermansen K. Dose- and Glucose-dependent effects of amino acids on insulin secretion from isolated mouse islets and clonal INS-1E beta-cells. Rev. Diabet. Stud. 5(4): 232-44, 2008.

 

  • Bertram H C, Jeppesen P B, Hermansen K. An NMR-based metabonomic investigation on effects of supplementation with Isosteviol or soy protein to diabetic KKAy mice. Diabetes, Obesity, and Metabolism, ;11(10):992-5, 2009.

 

  • Hong J, Jeppesen P B, Hermansen K. Effects of elevated fatty acid and glucose concentrations on pancreatic islets function in vitro. Diabetes, Obesity and Metabolism. Vol. 11, 4: 397-404, 2009.

 

  • Rani S, Mehta J P, Barron N, Doolan P, Jeppesen P B, et al. Decreasing Txnip mRNA and protein levels in pancreatic MIN6 cells reduces reactive oxygen species and restores glucose regulated insulin secretion. Cell Physiol. Biochem. 25(6): 667-74, 2010.

 

  • Hennessy E, Clynes M, Jeppesen P B, O´Driscoll L. Identification of microRNA with a role in glucose stimulated insulin secretion by expression profiling of MIN6 cells. Biochem Biophys Res. Commun 28;396(2):457-62, 2010.

 

  • Liu Z, Luo Y, Jeppesen PB, Gregersen S, Hermansen K. Amino acid-induced gene expression profiling in clonal Beta-cell line. Diabetes Metab Res Rev 27 (2): 120-76, 2011.

 

  • Chen X , Hermansen K, Xiao J, Bystrup S K, O'Driscoll L, Jeppesen P B. Isosteviol Has Beneficial Effects on Palmitate-Induced α-Cell Dysfunction and Gene Expression. PLoS One. 7(3):e34361, 2012.

 

  • Sandvei, M, Jeppesen, P B, Støen L , Litleskare S,  Johansen E,  Stensrud T,  Enoksen E, Hautala A,  Martinmäki K,  Kinnunen H, Tulppo M Jensen J. Sprint interval running increases insulin sensitivity in young healthy subjects. Archives Of Physiology And Biochemistry. Arch Physiol Biochem Jul;118(3):139-47, 2012.

 

  • Chen X, Jeppesen P B, Hermansen P B. Impact of glucagon-like peptide-1 (7-36) amide, isosteviol and 5-aminoimidazole-4-carboxamide 1-β-d-ribofuranoside on leucine-mediated α-cell dysfunction. Diabetes, Obesity and Metabolism. 14(11):1020-31, 2012.

 

  • Liu Z, Jeppesen P B, Gregersen S, Larsen L B, Hermansen K. Chronic Exposure to Leucine in vitro Induces β-Cell Dysfunction in INS-1E Cells and Mouse Islets. Journal of Endocrinology. 215(1):79-88, 2012.

 

  • Bertram HC, Larsen L B, Chen X and Jeppesen P B. Impact of high-carbohydrate diets on liver metabolism studied in rat model with a systems biology approach. J. Agric Food Chem. 18; 60 (2): 676-84, 2012.

 

  • Shen XX, Li HL, Pan L, Hong J, Xiao J, Hermansen K, Jeppesen PB, Li GW. Glucotoxicity and α cell dysfunction: involvement of the PI3K/Akt pathway in glucose-induced insulin resistance in rat islets and clonal αTC1-6 cells. Endocr Res. 2012;37(1):12-24. doi: 10.3109/07435800.2011.610855

 

  • Correia M, Neves-Petersen M T, Jeppesen P B, Gregersen S,  Petersen S B. UV-light exposure of Insulin: pharmaceutical implications upon covalent insulin dityrosine dimerization and disulphide bond photolysis. PLoS One, 2012;7(12):e50733. doi: 10.1371/journal.pone.0050733.

 

  • Hartvigsen ML, Jeppesen PB, Lærke HN, Njabe EN, Knudsen KE, Hermansen K. Concentrated arabinoxylan in wheat bread has beneficial effects as rye breads on glucose and changes in gene expressions in insulin-sensitive tissues of Zucker diabetic fatty (ZDF) rats. J Agric Food Chem. 2013 May 29;61(21):5054-63.

 

  • Brader L, Bjørnshave A, Christensen L P, Jeppesen P B and Hermansen Kjeld. Polyphenol-Rich bilberry ameliorates total cholesterol and LDL-cholesterol when implemented in the diet of Zucker diabetic fatty rats. The Review of Diabetic Studies . 10 (4):270-83, 2013.

 

 

  • Yang WC, Nammi S, Jeppesen PB, Cho WC. Complementary and alternative medicine for diabetes. Based Complement Alternat Med. 2013;2013:831068. doi: 10.1155/2013/831068. Epub 2013 Oct 3.

 

  • Gregersen S, Bystrup S, Overgaard A, Jeppesen P B, Søndergaard Thorup A C, Jensen E and Hermansen K. Effects of whey protein on glucose metabolism in normal Wistar rats and Zucker diabetic fatty (ZDF) rats. Review of Diabetic Studies. 10 (49: 252-69, 2013.

 

  • Bhattacharya S, Oksbjerg N, Young JF, Jeppesen PB. Caffeic acid, Naringenin and Quercetin enhance glucose stimulated insulin secretion and glucose sensitivity in INS-1E cells. Diabetes Obes Metab. 2014 Jul;16(7):602-12 doi: 10.1111/dom.12236. Epub 2013 Dec 2.

 

 

  • Thorup A C, Gregersen S, Jeppesen P B. Ancient wheat diet frlays diabetes development in a Type 2 Diabetes animal model Rev Diabet Stud. 2014 Fall-Winter;11(3-4):245-57Rev. doi: 10.1900/RDS.2014.11.245. Epub 2015 Feb 10.

 

  • Thorup A C, Lambert M N, Kahr H S, Bjerre M,  Jeppesen P B.  Intake of a novel red clover supplementation for 12-weeks improves bone status in healthy menopausal women.  Evid Based Complement Alternat Med. 2015;2015:689138. doi: 10.1155/2015/689138

 

  • Madsen S M, Thorup A C, Overgaard K, Jeppesen P B. High intensity interval training improves glycaemic control and pancreatic β cell function of type 2 diabetes patients. PLoS One. 2015 Aug 10;10(8):e0133286. doi: 10.1371/journal.pone.0133286.

 

 

  • Madsen S M, Thorup A C, Overgaard K, Bjerre M, Jeppesen P B. Functional and structural vascular adaptations following 8 weeks of low volume high intensity interval training in lower leg of type 2 diabetes patients and individuals at high risk of metabolic syndrome. Arch Physiol Biochem. 121(5): 178-186, 2015. DOI: 10.3109/13813455.2015.1087033.

 

  • Madsen S M, Thorup A C, Bjerre M, Jeppesen P B. Does 8 weeks of strenuous bicycle exercise improve diabetes-related inflammatory cytokines and free fatty acids in type 2 diabetes patients and individuals at high-risk of metabolic syndrome? Arch Physiol Biochem. 121(4): 129-138, 2015 DOI: 10.3109/13813455.2015.1082600.

 

  • Mellbye F B, Jeppesen P B, Hermansen K, Gregersen S. Cafestol, a bioactive substance in coffee, stimulates insulin secretion and increases glucose uptake in muscle cells: Studies in vitro. J. Nat. Products. 78:2447-2451, 2015. 1021/acs.jnatprod.5b00481

 

  • Wirngo F E, Lambert MNT, Jeppesen P B.(Review) The Physiological Effects of Dandelion (Taraxacum officinale) in Type 2 Diabetes Mellitus. Rev. Diabet. Stud. Summer-Fall;13(2-3):113-13, 2016.

 

 

  • Rustad P I, Sailer M, Cumming K T, Jeppesen P B, Kolnes L J, Sollie O, Franch J, Ivy J L, Daniel H, Jensen J. Intake of protein plus carbohydrate during the first two hours after exhaustive cycling improves performance the following day. PlosOne, 14;11(4):e0153229. doi: 10.1371/journal.pone.0153229. eCollection 2016.

 

  • Liu Z Jeppesen P B, Gregersen S, Larsen BL and Hermansen K. Chronic exposure to proline causes aminoacidotoxicity with impaired Beta-cell function: Studies in vitro. Rev Diabet Stud. 2016 Spring;13(1):66-78. doi: 10.1900/RDS.2016.13.

 

  • Bonde L, Shokouh P, Jeppesen P B,et al. Crosstalk between cardiomyocyte-rich perivascular tissue and coronary arteries is reduced in the Zucker Diabetic Fatty rat model of type-2 diabetes mellitus. Acta Physiol (Oxf). 2016 Apr 4. doi:
  1. 1111/apha.12685.

 

  • Mellbye F B, Jeppesen P B, Hermansen K, Gregersen S. Cafestol, a bioactive substance in coffee, stimulates insulin secretion and increases glucose uptake in muscle cells: Studies in vitro. J. Nat. Products. 78:2447-2451, 2015. 10.1021/acs.jnatprod.5b00481.

 

  • Mellbye FB, Jeppesen PB, Shokouh P, Laustsen C, Hermansen K, Gregersen S. Cafestol, a Bioactive Substance in Coffee, Has Antidiabetic Properties in KKAy Mice. J Nat Prod. 2017 Aug 1. doi: 10.1021/acs.jnatprod.7b00395.

 

  • Casanova LM, Gu W, Costa SS, Jeppesen PB. Phenolic Substances from Ocimum Species Enhance Glucose-Stimulated Insulin Secretion and Modulate the Expression of Key Insulin Regulatory Genes in Mice Pancreatic Islets. J Nat Prod. 2017 Dec 22;80(12):3267-3275. doi: 10.1021/acs.jnatprod.7b00699. Epub 2017 Dec 1.

 

  • Lambert M N T, Thorup A C, Hansen E S S, Jeppesen P B. Combined Red Clover isoflavones and probiotics potently reduce menopausal vasomotor symptoms. PLoS One. 2017 Jun 7;12(6):e0176590. doi: 10.1371/journal.pone.0176590.

 

  1. Shokouh P, Jeppesen PB, Hermansen K, Nørskov NP, Laustsen C, Jacques Hamilton-Dutoit S, Qi H, Stødkilde-Jørgensen H, Gregersen S. A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome. Nutrients. 2017 Dec 22;10(1). pii: E6. doi: 10.3390/nu10010006

 

  • Lambert M N T, Thybo C B, Lykkeboe S, Rasmussen L M, Frette X, Christensen L P, Jeppesen P B. Combined bioavailable isoflavones and probiotics improve bone status and estrogen metabolism in postmenopausal osteopenic women: a randomized controlled trial. Am J Clin Nutr. 2017 Aug 2. pii: ajcn153353. doi: 10.3945/ajcn.117.153353.

 

  • Lambert M N T, Hu LM, Jeppesen P B. A systematic review and meta-analysis of the effects of isoflavone formulations against estrogen-deficient bone resorption in peri- and postmenopausal women. Am J Clin Nutr. 2017 Aug 2. pii: ajcn151464. doi: 10.3945/ajcn.116.151464.

 

  • Lambert MNT, Jeppesen PB. Isoflavones and bone health in perimenopausal and postmenopausal women. Curr Opin Clin Nutr Metab Care. 2018 Nov;21(6):475-480. doi: 10.1097/MCO.0000000000000513.

 

  • Sollie O, Jeppesen PB, Tangen DS, Jernerén F, Nellemann B, Valsdottir D, Madsen K, Turner C, Refsum H, Skålhegg BS, Ivy JL, Jensen J. Protein intake in the early recovery period after exhaustive exercise improves performance the following day. J Appl Physiol (1985). 2018 Sep 13. doi: 10.1152/japplphysiol.01132.2017.

 

  • Shokouh P, Jeppesen PB, Hermansen K, Laustsen C, Stødkilde-Jørgensen H, Hamilton-Dutoit SJ, Søndergaard Schmedes M, Qi H, Stokholm Nørlinger T, Gregersen S. Effects of Unfiltered Coffee and Bioactive Coffee Compounds on the Development of Metabolic Syndrome Components in a High-Fat-/High-Fructose-Fed Rat Model. Nutrients. 2018 Oct 19;10(10). pii: E1547. doi: 10.3390/nu10101547

 

  • Rafiq S, Jeppesen PB. Is Hypovitaminosis D Related to Incidence of Type 2 Diabetes and High Fasting Glucose Level in Healthy Subjects: A Systematic Review and Meta-Analysis of Observational Studies. Nutrients. 2018 Jan 10;10(1). pii: E59. doi: 10.3390/nu10010059

 

  • Rafiq S and Jeppesen P B. Body Mass Index, Vitamin D, and Type 2 Diabetes: A Systematic Review and Meta-Analysis. Nutrients 2018, 10(9), 1182; https://doi.org/10.3390/nu10091182

 

  • Gu, W., Rebsdorf, A., Hermansen, K., Gregersen, S. & Jeppesen, P. B. The Dynamic Effects of Isosteviol on Insulin Secretion and Its Inability to Counteract the Impaired β-Cell Function during Gluco-, Lipo-, and Aminoacidotoxicity: Studies In Vitro., 26 jan. 2018, I : Nutrients. 10, s. E127.

 

  • Samuel P, Ayoob KT, Magnuson BA, Wölwer-Rieck U, Jeppesen PB, Rogers PJ, Rowland I, Mathews R. Stevia Leaf to Stevia Sweetener: Exploring Its Science, Benefits, and Future Potential. J Nutr. 2018 Jul 1;148(7):1186S-1205S. doi: 10.1093/jn/nxy102

 

  • Patel S, Alvarez-Guaita A, Melvin A, Rimmington D, Dattilo A, Miedzybrodzka EL, Cimino I, Maurin AC, Roberts GP, Meek CL, Virtue S, Sparks LM, Parsons SA, Redman LM, Bray GA, Liou AP, Woods RM, Parry SA, Jeppesen PB, et al. GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans. Cell Metab. 2019 Jan 2. pii: S1550-4131(18)30753-8. doi: 10.1016/j.cmet.2018.12.016

 

 

  • Sørensen LE, Jeppesen P B, ChristiansenC B, Hermansen K and Gregersen S. Nordic Seaweed and Diabetes Prevention: Exploratory Studies in KK-Ay Mice. Nutrients. 2019 Jun 25;11(6). pii: E1435. doi: 10.3390/nu11061435.

 

  • Maxel T, Smidt K, Petersen CC, Honoré B, Christensen AK, Jeppesen PB, Brock B, Rungby J, Palmfeldt J, Larsen A. The zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells. Sci Rep. 2019 Jun 13;9(1):8589. doi: 10.1038/s41598-019-44954-1.

 

  • Gu W, Rebsdorf A, Anker C, Gregersen S, Hermansen K, Geuns J M C and Jeppesen P B. Steviol Glucuronide, a Metabolite of Steviol Glycosides, Potently Stimulates Insulin Secretion from Isolated Mouse Islets: Studies in Vitro. Endocrinology, Diabetes & Metabolism; August 2019. Endocrinol Diabetes Metab. 2019 Sep 6;2(4):e00093. doi: 10.1002/edm2.93.

 

  • Bundgaard Anker CC, Rafiq S, Jeppesen PB. Effect of Steviol Glycosides on Human Health with Emphasis on Type 2 Diabetic Biomarkers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 2019 Aug 21;11(9). pii: E1965. doi: 10.3390/nu11091965

 

  • Shokouh P, Jeppesen PB, Christiansen CB, Mellbye FB, Hermansen K, Gregersen S. Efficacy of Arabica Versus Robusta Coffee in Improving Weight, Insulin Resistance, and Liver Steatosis in a Rat Model of Type-2 Diabetes. Nutrients. 2019 Sep 3;11(9). pii: E2074. doi: 10.3390/nu11092074.

 

  • Valsdottir T D, Henriksen C, Odden N, Nellemann B, Jeppesen P B, Hisdal J, Westerberg A C  and  Jensen J. Effect of a Low-Carbohydrate High-Fat Diet and a Single Bout of Exercise on Glucose Tolerance, Lipid Profile and Endothelial Function in Normal Weight Young Healthy Females. Physiol., 19 December 2019| https://doi.org/10.3389/fphys.2019.01499.

 

  • Nielsen LLK, Lambert MNT and Jeppesen PB. The Effect of ingesting Carbohydrate and Proteins on Athletic Performance: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients, Nutrients 2020, 12(5), 1483; https://doi.org/10.3390/nu12051483

 

  • Poulsen NB, Lambert MNT, Jeppesen PB. The Effect of Plant Derived Bioactive Compounds on Inflammation - A Systematic Review and Meta-Analysis. Mol Nutr Food Res. 2020 Aug 6:e2000473.

 

  • Lambert MNT, Langkjer ST, Jeppesen PB. Isoflavones have therapeutic efficacy inoestrogen deficiency]. Ugeskr Laeger. 2020 May 18;182(21):V11190643.

 

 

  • Dahl MA, Areta JL, Jeppesen PB, Birk JB, Johansen EI, Ingemann-Hansen T, Hansen M, Skålhegg BS, Ivy JL, Wojtaszewski JFP, Overgaard K, Jensen J. Coingestion of protein and carbohydrate in the early recovery phase, compared with carbohydrate only, improves endurance performance despite similar glycogen degradation and AMPK phosphorylation. J Appl Physiol (1985). 2020 Aug 1;129(2):297-310. doi: 10.1152/japplphysiol.00817.2019. Epub 2020 Jun 25

 

  • Berenji AS, Eftedal I, Pedersen M, Jeppesen PB, Nørregaard R, Matchkov VV. Endothelial dysfunction in small arteries and early signs of atherosclerosis in ApoE knockout rats. Sci Rep. 2020 Sep 17;10(1):15296. doi: 10.1038/s41598-020-72338-3.

 

 

  • Thorup A C, Kristensen H L, Kidmose U, Christensen L P, Fretté X C, Clausen M R, Hansen S M, Jeppesen P B. Do selected traditional cultivars of strong and bitter vegetables improve the health status of type 2 diabetics. Nutrients. Nutrients 2021, 13, 1813. https://doi.org/10.3390/nu13061813.

 

  • Rafiq S and Jeppesen PB. Insulin Resistance Is Inversely Associated with the Status of Vitamin D in Both Diabetic and Non-Diabetic Populations. Nutrients 2021, 13, 1742. https://doi.org/10.3390/nu1306174.

 

 

 

  • Gu W, Anker CCB, Christiansen CB, Moede T, Berg-Gren PO, Hermansen K, Gregersen S and Jeppesen PB. Pancreatic 𝛽-cells inhibits glucagon secretion from 𝛼-cells: an in vitro demonstration of 𝛼-𝛽 cell interaction. Nutrients, Nutrients. 2021 Jun 30;13(7):2281. doi: 10.3390/nu13072281.

 

  • Wilken M, Lambert MNT, Jeppesen PB. Effects of anthocyanin rich berries on risk factors for metabolic syndrome: A Systematic Review and Meta-Analysis. The Review of Diabetic Studies journal, Submitted Sept. 2021.

 

  • Sweeney C, Lambert MNT, Langkjer S, Jeppesen PB. A Systematic Review and Meta-Analysis of In-Vitro MCF-7 Studies and the Effect of Isoflavones on Proliferation. Journal of Agricultural and Food Chemistry. Submitted Sept. 2021.

 

  • Sweeney C, Lambert MNT, Langkjer S, Jeppesen PB. Red Clover Isoflavones and the Isothiocyanate Sulforaphane Inhibit In-Vitro MCF-7 Cell Growth Compared to Endogenous Estrogen. JNP, Submitted Sept. 2021.

 

 

 

 

 

 

Selected Patents:

 

  • Jeppesen P B, POULSEN A K , Mønster D. Title: Laundry detergent. Priority: PA 2011/2254.

 

  • Jeppesen P B, Gregersen G, Hermansen K. Title: “A substance for the use in a dietary supplementation or the preparation of a medicament for the treatment of non-insulin dependent diabetes mellitus, hypertension and/or the metabolic syndrome.PCT Application no: WO 0156959 A1. Priority: PA 2000 00163, DK.( pp74, fig. 13).

 

  • Jeppesen P B, Hermansen K. Title:  “The present invention relates to a composition for the prevention of insulin resistance and/or treatment of conditions or diseases associated with insulin resistance”. Priority PA 2006 01200 , DK

 

  • Jeppesen P B, Hermansen K. Title: “Treatment of insulin resistance or diseases associated with insulin resistance”. Priority: PA 2007/01274, DK.

 

  • Jeppesen P B, Hermansen K and Aarhus University. Title: Elevation of the plasma HDL-cholesterol level. Priority: PA Priority: 2007/01748, DK.

 

 

  • Jeppesen P B, Lambert M, Thorup AC, Jensen M M. Titel: Product comprising red clover extract and methods for producing the same: Priority: PA 2013/ 00233DK.

 

  • Jeppesen P B, Laursen S. Compositions for use in restoring muscle glycogen and/or muscle mass. Priority: PA 2013 70226

 

  • Jeppesen P B, Mønster D. Titel: Composition for protection of plants, fruit and vegetables. Priority: PA 2015 70568 DK01

 

  • Jeppesen P B, Mellbye F B, Hermansen K, Gregersen S. Titel: Cafestol. Priority: PCT/DK2015/050139

 

  • Jeppesen P B. Titel: Treatment of invasive pulmonary aspergillosis. Priority: PA 2015 70873

 

  • Jeppesen PB, Mønster D. ANTIFUNGAL AGENT. PCT/DK2016/050467 /WO 2017/108065 A1

 

 

 

 

 

 

Documentary and science films:

  • Title: “The man from the rainforest”, producer Nature and Science, Copenhagen. Shot in South America 2009-2010. Has been shown at DR 2011 and 12. Supported by DANIDA and Ministry of Science, Technology and Innovation, Denmark.
  • Title: “Maxveg projektet” 4 small documentary film , poducer KAMPAS film, Copenhagen. Shot in Denmark 2011 and 2012. Has been shown at DR 2013: 1) MAXVEG- projektet; 2)  MAXVEG – Type 2 Diabtes; 3) MAXVEG - Den bitre smag; 4) MAXVEG-Livstilssygdomme.
  • Fedmeforsker advarer: Farligt sukker (high fructose corn syrup) på vej til Europa – DR- TV-Avisen 28-10-2014.
  • Effekten af rødkløver ekstrakt på overgangsalder og knogleafkalkning – DR-TV Avisen(http://www.youtube.com/watch?v=LbqUIcq4NsM ) 08-08-2014.

              

 

 

Books:

 

  • Monograph: Jeppesen P. B.  “The Safety of Stevioside” Chapter 3 “ Can stevioside be a new useful drug in the treatment of type 2 diabetes and the metabolic syndrome” pp 25-30, ed. Jan M. C. Geuns & Johan G Buyse: Euprint ed., Heverlee, Belgium, 2004

 

  • Xiao J, Kruhøffer M, Jeppesen P B, Abudula R, Nordentoft I, Ørntoft T, Hermansen K. Changes of gene expression in INS-1 cells: The implication in lipotoxicity pp 1-36, in Unraveling Metabolism with Microarrays and Metabolomic approached, ed. A. Berger; Marcel Dekker, New York, 2003.

 

  • Jeppesen P. B. Chapter “ Stevia” Book title: “Encyclopedia of Dietary Supplements” ed. Paul Coates et al. Marcel Dekker, New York, 2004.

 

  • Monograph: Jeppesen P. B. “ Stevia components improve glucose homeostasis in Type 2 Diabetes? - A new promising drug” ” Chapter 10 Proceedings of the 2nd Stevia symposium: “Steviol glycosides: technical and pharmacological aspects”, June 27th 2008, KULeuven, Belgium pp. 151-179, ISBN: 9789074253-031

 

  • Monograph: Jeppesen P.B. “Isosteviol elevates plasma HDL-cholesterol level. Chapter 13 Proceedings of the 4th Stevia symposium: June 29 th 2010, KULeuven Belgium PP. 173-189, ISBN:978-90-742-53130.

 

  • Monograph: Jeppesen P.B. From field to fork: Does similar intake in degree of sweetness of Rebaudioside A have favourable health effects compared to high fructose corn syrup and aspartame ?.

 

  • Anthology: Sugar and Modernity in Latin America. Edited by  Vinicius Mariano de Carvalho, Susanne Højlund, Per Bendix Jeppesen and Karen-Margrethe Simonsen. Aarhus University Press; ISBN: 9788771241105.

 

  • Kål Kogebogen- Spis bitterstoffer fra kål og rodfrugter og slip for type 2 diabetes. Gyldendal 2020- ISBN: 978-97-02-29886-4.

 

 

Selected Public communication:

  • Jeppesen, Per Bendix. Tikkende bombe under sukkerindustrien. I: Boersen. 23 okt. s. 6-7, 2008

 

  • Jeppesen, Per Bendix . Måske kan du snart spise sundt slik : Meget tyder på, at din lightsodavand eller dine vingummier inden længe kan være sødet med stevia, et nyt naturligt sødestof. : I Form. April; nr. 6: 72-75, 2009.

 

 

  • Jeppesen, Per Bendix . 300 gange sødere end sukker : Den lille stevia busk indeholder et naturligt og kaloriefrit sødestof.. I: Samvirke. Jan:. 28-29. 2009.

 

  • Jeppesen, P. B. 28 jan. 2015 2, 69952Sød Nyhed: Aarhus-forskeren Per Bendix Jeppesen er glad . I årevis har han kæmpet for at få det naturlige sødemiddel Stevia godkendt. 69952, Århus Stiftstidende

 

  • Jeppesen, P. B. Fedmeforsker slår alarm: Farligt sukker er på vej til Europa: Det er billigere- men også farligere end almindeligt sukker. Og så er det på vej til Europa

 28 okt. 2014 Jyllands-Posten

 

 

 

Selected Congresses:

 

  • European Association for the study of Diabetes (EASD), Wienna, Austria, Sept. 1996. Jeppesen P B, Gregersen S, Hermansen K. Stevioside and steviol stimulate insulin secretion from isolated mouse islets. Diabetologia; A125, 472, 1996.

 

  • Danish Endocrine Society. 1997. Jeppesen P B, Gregersen S, Hermansen K. The two diterpenes, stevioside and steviol, stimulate insulin secretion from isolated islets.

 

 

  • International Diabetes Federation Congress (IDF), Helsinki, Finland, 1997. Jeppesen P B, Gregersen S, Hermansen K. Hypo-glycaemic and insulinotropic effekts of stevioside in the non-insulin dependent GK rat. Diabetologia; A136, 529, 1997.

 

  • Danish Endocrine Society. dec. 1998. Jeppesen P B, Gregersen S, Hermansen K. Anti-hyperglucaemic and insulinotropic effecs of stevioside in the diabetic GK-rat.

 

 

  • ADDDG-Symposium (Novo Nordisk), Cumbria, England, maj 12-15 , 1998.

 

  • EASD, Barcelona, Spain, sept. 1998. Jeppesen P B, Gregersen S, poulsen, R C, Hermansen K. Stevioside stimulates insulin secretion and upregulates insulin II mRNA in the pancreatic beta-cells independent of cAMP and K-ATP-activity. Diabetologia; A125, 472, 1998.

 

  • Danish Endocrine Society. Jan. 2000. Jeppesen P B, Gregersen S, Hermansen K. Glucose upregulates phosphodiesterase-3B (PDE-3B) expression in the pancreatic beta-cell line MIN-6.

 

  • International Diabetes Federation Congress (IDF), Mexico City, Mexico, 2000. . Jeppesen P B, Gregersen S, Hermansen K. Effects of long-term treatment with stevisoide on the type 2 Diabetic Goto-Kakizaki (GK) rats. Diabetes Research and Clinical Practice; S393 (P1535)

 

 

  • Danish Endocrine Society. Jan. 2001. Jeppesen P B, Gregersen S, Hermansen K. Effects of long-term treatment with stevisoide on the type 2 Diabetic Goto-Kakizaki (GK) rats. Abstract No. 7.

 

  • 31`st annual synposium of the Scandinavian Society for Laboratory Society for Laboratory animal Science, Aarhus , Denmark, May 2001 Jeppesen PB, Gregersen S, Hermansen K. Effects of long-term treatment with stevisoide on the type 2 Diabetic Goto-Kakizaki (GK) rats: - potential as a new antidiabetic drug Abstract No. A31, 60

 

 

  • 6`th International European Scientfic Cooperative on Phytotherapy (ESCOP) Symposium, Bonn, Germany, May 2001: Jeppesen PB, Gregersen S, Hermansen K Effects of long-term treatment with stevisoide on the type 2 Diabetic Goto-Kakizaki (GK) rats: - potential as a new antidiabetic drug.

 

  • EASD, Glasgow, UK, Sept. 2001. Gregersen S, Jeppesen PB, Holst JJ. Hermansen K. Acute effects of the diterpene glucoside, stevioside,  in type II diabeteic patients. Diabetologia; A 236, 905.

 

  • EASD, Glasgow, UK, Sept. 2001. Jeppesen PB, Gregersen S, Hermansen K Effects of long-term treatment with stevioside on the type 2 Diabetic Goto-Kakizaki (GK) rats: - potential as a new antidiabetic drug. Diabetologia; A 227, 872.

 

  • The 20th International Symposium on Diabetes and Nutrition, 2002, Samos, Greece. Jeppesen PB, Gregersen S, Hermansen K. Effects of long-term treatment with stevioside on the type 2 Diabetic Goto-Kakizaki (GK) rats: - potential as a new antidiabetic drug.

 

  • International Diabetes Federation Congress (IDF), Paris, France, 2003. Jeppesen P B, Rolfsen S E D, Agger A, Gregersen S,  Colombo C, Xiao J,  Hermansen K. Stevioside in combination with soy-based dietary supplement exerts a beneficial effect on type 2 diabetic GK rats: Multifactorial treatment of type 2 diabetes and the metabolic syndrome. Diabetologia; A293, 847.

 

  • Danish Endocrine Society. Jan. 2004. Jeppesen P B, Rolfsen S E D, Agger A, Gregersen S, Colombo C, Xiao J,  Hermansen K. Stevioside in combination with soy-based dietary supplement exerts a beneficial effect on type 2 diabetic GK rats: Multifactorial treatment of type 2 diabetes and the metabolic syndrome.. Abstract No. 9.

 

  • 22nd ISDN symposium (Sastaholm, Sweden. Jeppesen P B, Rolfsen S E D, Agger A, Gregersen S, Colombo C, Xiao J,  Hermansen K Stevioside in combination with soy-based dietary supplement exerts a beneficial effect on type 2 diabetic GK rats: Multifactorial treatment of type 2 diabetes and the metabolic syndrome. Abstract no. 2., 2004

 

  • 2004 International Congress on Natural products research. Jeppesen P B, Rolfsen S E D, Agger A, Gregersen S, Colombo C, Xiao J,  Hermansen K Stevioside in combination with soy-based dietary supplement exerts a beneficial effect on type 2 diabetic GK rats: Multifactorial treatment of type 2 diabetes and the metabolic syndrome. Abstract no. 91, 2004

 

  • 53rd Annual congress of the Society for Medicinal Plant research, Florence 21-25 august, Jeppesen P B, Rolfsen S E D, Hermansen K Stevioside in combination with soy-based dietary supplement exerts a beneficial effect on type 2 diabetic GK rats. Abstract no. P 180, 2005

 

  • 42nd Annual Metting of the European Association for the Study of Diabetes. Jeppesen P B, Barriocanal L, Meyer M T, Palacios M, Canete F, Benitez S, Logwin S, Schupmann Y, Benitez G, Jimenez  J T. Efficacy and tolerability of oral stevioside in patients with type 2 diabetes: a long-term, randomized, double-blinded, placebo-controlled study. Abstract no P 843, 2006.

 

  • 19th World Diabetes Congress, International Diabetes Federation, Cape Town, South Africa. Jeppesen P B, Nordentoft I, Abudula R,  Hong J and Hermansen k. Isosteviol and soy bean protein isolate may be a novel oral anti-diabetic agents for treatment of type 2 diabetes and the metabolic syndrome - A in vivo study on diabetic KKAy-mice. Diabetic Medicine A: 836 P: 305, 2006.

 

  • Danish Endocrine Society. Jan. 2007 (Aalborg). Jeppesen P B, Nordentoft I, Abudula R, Hong J and Hermansen k. Isosteviol and soy bean protein isolate may be a novel oral anti-diabetic agents for treatment of type 2 diabetes and the metabolic syndrome – a in vivo study on diabetic KKAy-mice. Oral A: 56

 

  • Jeppesen P B, Nordentoft I, Abudula R,  Hong J and Hermansen k. EASD Amsterdam  Sept. 2007. Isosteviol as novel oral anti-diabetic agent for treatment of type 2 diabetes and the metabolic syndrome - a in vivo study on diabetic KKAy-mice. Diabetologia, oral presentation, A0217, 2007

 

  • Danish Endocrine Society. Jan 2008 (Aarhus). Jeppesen P B, Nordentoft I, Abudula R, Hong J and Hermansen k. Increased insulin and glucose sensitivity and changes in the expression profile of key insulin regulatory genes and beta cell transcription factors in diabetic KKAy-mice after feeding with a soy bean protein rich diet high in isoflavone content. Oral A. 53

 

  • 5th World Congress on Prevention of Diabetes and its Complications (WCPD 2008) Helsinki, Finland , June 2008. Jeppesen P B, Nordentoft I, Abudula R, Hong J and Hermansen k. Isosteviol as novel oral anti-diabetic agent for treatment of type 2 diabetes and the metabolic syndrome - a in vivo study on diabetic KKAy-mice. Poster no. 19-05.

 

  • The 2nd Stevia symposium, KULeuven, Belgium , June 2008. Jeppesen P. B. “ Stevia components improve glucose homeostasis in Type 2 Diabetes? - A new promising drug” Proceedings of the 2nd Stevia symposium: pp. 151-179. Oral presentation

 

  • 13 th International Congress of Endocrinology (ICE), Rio de Janeiro, Brazil, Nov. 8-12, 2008. Jeppesen P B, Nordentoft I, Abudula R, Hong J and Hermansen k. Isosteviol as novel oral anti-dibetic agents for the treatment of type 2 diabetes and the metabolic syndrome – a in vivo study on diabetic KKAY-mice. Oral presentation. OP 063 – 2008.

 

  • Jeppesen P B, Chen X, Liu Z and Hermansen k. EASD, Vienna, Austria,  Sept. 2009. Isosteviol elevates plasma HDL-cholesterollevel - A potential new drug for the treatment of coronary heart disease. Diabetologia,  A , 2009.

 

  • The 27th International Symposium on Diabetes and Nutrition Study Group (DNSG). Potsdam, Germany, June 2009. Jeppesen P B, Nordentoft I, Abudula R, Hong J and Hermansen k. Isosteviol as novel oral anti-diabetic agents for treatment of type 2 diabetes and the metabolic Syndrome  - an in vivo study in diabetic KKAy-mice. Oral presentation. A 38

 

  • The 4th Stevia symposium: June 29 th 2010, KULeuven, Belgium, 2010 . Jeppesen PB. Isosteviol elevates plasma HDL-cholesterol level. Proceedings of the 4th Stevia Symposium. PP. 173-189. Oral Presentation.

 

  • 28 th International Symposium on Diabetes and Nutrition study group, Oslo, Norway , June 2010. Jeppesen P B, Nordentoft I, Abudula R, Hong J and Hermansen k. Isosteviol as novel oral anti-diabetic agents for treatment of type 2 diabetes and the metabolic Syndrome. No. VIII.

 

  • 30th International Symposium on Diabetes and Nutrition study group, Athens, Greece. June 2012. Overgaard A., Brader L.H., Jeppesen P B., Hermansen K. The effect of bioactive compounds from bilberry and blackcurrant in the treatment of type 2 diabetes. OP 25.

 

  • 30th International Symposium on Diabetes and Nutrition study group, Athens, Greece. June 2012. Thorup A, Jeppesen P B., Hermansen K. Investigating the health promoting effects of vegetables on people with type 2 diabetes and the metabolic syndrome. OP 22

 

  • VI simposio internacional del Kaá HE´E^- Stevia- Reunion Internaciomal de la Federacion Americana de la Stevia –FAS, Asuncion, Paraguay Nov. 2012. Jeppesen P B. Stevia and its impact on health – Food or Medicine ? oral presentation.

 

  • 7th International Conference on Diabetes & Obesity, October 24-25, 2013 – Riga Stradins Unviersity, Latvia. Jeppesen P B. Stevia and its Impact on Health - Food or Medicine? Oral presentation.

 

  • Jeppesen P. B., Elsøe M, Laustsen C. EASD, Vienna, Austria Sept. 2014. Does excessive consumption of high fructose corn syrup, aspartame or rebaudioside A affect insulin sensitivity and regulatory genes in liver and muscles? P 773

 

  • Thorup A.C., Kristensen H.L., Jeppesen P. B. Vienna, Austria Sept. 2014. Secondary metabolites from vintage vegetables improve the health status of patients with type 2 diabetes when compared to equivalent modern vegetables. P 784

 

  • 33rd international Symposium on Diabetes and Nutrition study group, Toronto, Canada June 2015. Madsen S. M., Thorup A.C., Overgaard K and Jeppesen P.B. High intensity interval training improves glycaemic control and pancreatic beta-cell function of type 2 diabetes patients. OP 6.

 

  • Workshop at Cambridge University. 10-11 December 2015, Cambrige, England. Why Is Exercise Good For Us? Jeppesen PB, Madsen SM.  Complementing Genetics For Better Metabolic Regulation. Danish Diabetes Academy & Cambridge Metabolic Network. P: 25.

 

  • 35th international Symposium on Diabetes and Nutrition study group, Skagen, Denmark, June 2017. Jeppesen PB. Controversies about sweeteners consumption and health: State of the science.

 

  • 35th international Symposium on Diabetes and Nutrition study group, Skagen, Denmark, June 2017. Rebsdof AL, Jeppesen PB.The effect of TX531 on islet of Langerhans, human skeletal muscle call and hepatocytes in relation to type 2 diabetes and non-alcoholic fatty liver.

 

 

  • 35th international Symposium on Diabetes and Nutrition study group, Skagen, Denmark, June 2017. Luna B P, Jeppesen PB. The effect of fructose in measures of metabolic disease: A Systematic review and meta-analysis of controlled human trials.
  • 36th DNSG International Symposium (Opatija, Croatia), 2018. Chairman Jeppesen PB. Low calorie sweeteners and microbiome: Implications for diabetes.

 

  • 37th DNSG International Symposium (Kerkrade, The Netherlands), 2019 Nielsen LL and Jeppesen PB. The effect of a new plant based product on the recovery and performance of healthy individuals – with potential beneficial effects on type 2 diabetes patients.

 

  • 37th DNSG International Symposium (Kerkrade, The Netherlands), 2019. Poulsen NB, Hvas CL, Rud C and Jeppesen PB. Effects of plant-based nutrition drinks on chronic inflammatory bowel disease.