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Nina Aagaard Poulsen

Effects of breed and casein genetic variants on protein profile in milk from Swedish Red, Danish Holstein, and Danish Jersey

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Standard

Effects of breed and casein genetic variants on protein profile in milk from Swedish Red, Danish Holstein, and Danish Jersey. / Gustavsson, Frida; Buitenhuis, Albert Johannes; Johansson, M; Bertelsen, Henriette Pasgaard; Glantz, M; Poulsen, Nina Aagaard; Månsson, H Lindmark; Stålhammer, Hans; Larsen, Lotte Bach; Bendixen, Christian; Paulsson, M; Andrén, A.

I: Journal of Dairy Science, Bind 97, Nr. 6, 06.2014, s. 3866-3877.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Gustavsson, F, Buitenhuis, AJ, Johansson, M, Bertelsen, HP, Glantz, M, Poulsen, NA, Månsson, HL, Stålhammer, H, Larsen, LB, Bendixen, C, Paulsson, M & Andrén, A 2014, 'Effects of breed and casein genetic variants on protein profile in milk from Swedish Red, Danish Holstein, and Danish Jersey', Journal of Dairy Science, bind 97, nr. 6, s. 3866-3877. https://doi.org/10.3168/jds.2013-7312

APA

Gustavsson, F., Buitenhuis, A. J., Johansson, M., Bertelsen, H. P., Glantz, M., Poulsen, N. A., Månsson, H. L., Stålhammer, H., Larsen, L. B., Bendixen, C., Paulsson, M., & Andrén, A. (2014). Effects of breed and casein genetic variants on protein profile in milk from Swedish Red, Danish Holstein, and Danish Jersey. Journal of Dairy Science, 97(6), 3866-3877. https://doi.org/10.3168/jds.2013-7312

CBE

Gustavsson F, Buitenhuis AJ, Johansson M, Bertelsen HP, Glantz M, Poulsen NA, Månsson HL, Stålhammer H, Larsen LB, Bendixen C, Paulsson M, Andrén A. 2014. Effects of breed and casein genetic variants on protein profile in milk from Swedish Red, Danish Holstein, and Danish Jersey. Journal of Dairy Science. 97(6):3866-3877. https://doi.org/10.3168/jds.2013-7312

MLA

Vancouver

Author

Gustavsson, Frida ; Buitenhuis, Albert Johannes ; Johansson, M ; Bertelsen, Henriette Pasgaard ; Glantz, M ; Poulsen, Nina Aagaard ; Månsson, H Lindmark ; Stålhammer, Hans ; Larsen, Lotte Bach ; Bendixen, Christian ; Paulsson, M ; Andrén, A. / Effects of breed and casein genetic variants on protein profile in milk from Swedish Red, Danish Holstein, and Danish Jersey. I: Journal of Dairy Science. 2014 ; Bind 97, Nr. 6. s. 3866-3877.

Bibtex

@article{764dc20d9a0b43edbd7fd8b11f889f29,
title = "Effects of breed and casein genetic variants on protein profile in milk from Swedish Red, Danish Holstein, and Danish Jersey",
abstract = "In selecting cows for higher milk yields and milk quality, it is important to understand how these traits are affected by the bovine genome. The major milk proteins exhibit genetic polymorphism and these genetic variants can serve as markers for milk composition, milk production traits, and technological properties of milk. The aim of this study was to investigate the relationships between casein (CN) genetic variants and detailed protein composition in Swedish and Danish dairy milk. Milk and DNA samples were collected from approximately 400 individual cows each of 3 Scandinavian dairy breeds: Swedish Red (SR), Danish Holstein (DH), and Danish Jersey (DJ). The protein profile with relative concentrations of α-lactalbumin, β-lactoglobulin, and αS1-, αS2-, κ-, and β-CN was determined for each milk sample using capillary zone electrophoresis. The genetic variants of the αS1- (CSN1S1), β- (CSN2), and κ-CN (CSN3) genes for each cow were determined using TaqMan SNP genotyping assays (Applied Biosystems, Foster City, CA). Univariate statistical models were used to evaluate the effects of composite genetic variants, αS1-β-κ-CN, on the protein profile. The 3 studied Scandinavian breeds differed from each other regarding CN genotypes, with DH and SR having similar genotype frequencies, whereas the genotype frequencies in DJ differed from the other 2 breeds. The similarities in genotype frequencies of SR and DH and differences compared with DJ were also seen in milk production traits, gross milk composition, and protein profile. Frequencies of the most common composite αS1-β-κ-CN genotype BB/A2A2/AA were 30% in DH and 15% in SR, and cows that had this genotype gave milk with lower relative concentrations of κ- and β-CN and higher relative concentrations of αS-CN, than the majority of the other composite genotypes in SR and DH. The effect of composite genotypes on relative concentrations of the milk proteins was not as pronounced in DJ. The present work suggests that a higher frequency of BB/A1A2/AB, together with a decrease in BB/A2A2/AA, could have positive effects on DH and SR milk regarding, for example, the processing of cheese",
author = "Frida Gustavsson and Buitenhuis, {Albert Johannes} and M Johansson and Bertelsen, {Henriette Pasgaard} and M Glantz and Poulsen, {Nina Aagaard} and M{\aa}nsson, {H Lindmark} and Hans St{\aa}lhammer and Larsen, {Lotte Bach} and Christian Bendixen and M Paulsson and A Andr{\'e}n",
year = "2014",
month = jun,
doi = "10.3168/jds.2013-7312",
language = "English",
volume = "97",
pages = "3866--3877",
journal = "Journal of Dairy Science",
issn = "0022-0302",
publisher = "Elsevier Inc.",
number = "6",

}

RIS

TY - JOUR

T1 - Effects of breed and casein genetic variants on protein profile in milk from Swedish Red, Danish Holstein, and Danish Jersey

AU - Gustavsson, Frida

AU - Buitenhuis, Albert Johannes

AU - Johansson, M

AU - Bertelsen, Henriette Pasgaard

AU - Glantz, M

AU - Poulsen, Nina Aagaard

AU - Månsson, H Lindmark

AU - Stålhammer, Hans

AU - Larsen, Lotte Bach

AU - Bendixen, Christian

AU - Paulsson, M

AU - Andrén, A

PY - 2014/6

Y1 - 2014/6

N2 - In selecting cows for higher milk yields and milk quality, it is important to understand how these traits are affected by the bovine genome. The major milk proteins exhibit genetic polymorphism and these genetic variants can serve as markers for milk composition, milk production traits, and technological properties of milk. The aim of this study was to investigate the relationships between casein (CN) genetic variants and detailed protein composition in Swedish and Danish dairy milk. Milk and DNA samples were collected from approximately 400 individual cows each of 3 Scandinavian dairy breeds: Swedish Red (SR), Danish Holstein (DH), and Danish Jersey (DJ). The protein profile with relative concentrations of α-lactalbumin, β-lactoglobulin, and αS1-, αS2-, κ-, and β-CN was determined for each milk sample using capillary zone electrophoresis. The genetic variants of the αS1- (CSN1S1), β- (CSN2), and κ-CN (CSN3) genes for each cow were determined using TaqMan SNP genotyping assays (Applied Biosystems, Foster City, CA). Univariate statistical models were used to evaluate the effects of composite genetic variants, αS1-β-κ-CN, on the protein profile. The 3 studied Scandinavian breeds differed from each other regarding CN genotypes, with DH and SR having similar genotype frequencies, whereas the genotype frequencies in DJ differed from the other 2 breeds. The similarities in genotype frequencies of SR and DH and differences compared with DJ were also seen in milk production traits, gross milk composition, and protein profile. Frequencies of the most common composite αS1-β-κ-CN genotype BB/A2A2/AA were 30% in DH and 15% in SR, and cows that had this genotype gave milk with lower relative concentrations of κ- and β-CN and higher relative concentrations of αS-CN, than the majority of the other composite genotypes in SR and DH. The effect of composite genotypes on relative concentrations of the milk proteins was not as pronounced in DJ. The present work suggests that a higher frequency of BB/A1A2/AB, together with a decrease in BB/A2A2/AA, could have positive effects on DH and SR milk regarding, for example, the processing of cheese

AB - In selecting cows for higher milk yields and milk quality, it is important to understand how these traits are affected by the bovine genome. The major milk proteins exhibit genetic polymorphism and these genetic variants can serve as markers for milk composition, milk production traits, and technological properties of milk. The aim of this study was to investigate the relationships between casein (CN) genetic variants and detailed protein composition in Swedish and Danish dairy milk. Milk and DNA samples were collected from approximately 400 individual cows each of 3 Scandinavian dairy breeds: Swedish Red (SR), Danish Holstein (DH), and Danish Jersey (DJ). The protein profile with relative concentrations of α-lactalbumin, β-lactoglobulin, and αS1-, αS2-, κ-, and β-CN was determined for each milk sample using capillary zone electrophoresis. The genetic variants of the αS1- (CSN1S1), β- (CSN2), and κ-CN (CSN3) genes for each cow were determined using TaqMan SNP genotyping assays (Applied Biosystems, Foster City, CA). Univariate statistical models were used to evaluate the effects of composite genetic variants, αS1-β-κ-CN, on the protein profile. The 3 studied Scandinavian breeds differed from each other regarding CN genotypes, with DH and SR having similar genotype frequencies, whereas the genotype frequencies in DJ differed from the other 2 breeds. The similarities in genotype frequencies of SR and DH and differences compared with DJ were also seen in milk production traits, gross milk composition, and protein profile. Frequencies of the most common composite αS1-β-κ-CN genotype BB/A2A2/AA were 30% in DH and 15% in SR, and cows that had this genotype gave milk with lower relative concentrations of κ- and β-CN and higher relative concentrations of αS-CN, than the majority of the other composite genotypes in SR and DH. The effect of composite genotypes on relative concentrations of the milk proteins was not as pronounced in DJ. The present work suggests that a higher frequency of BB/A1A2/AB, together with a decrease in BB/A2A2/AA, could have positive effects on DH and SR milk regarding, for example, the processing of cheese

U2 - 10.3168/jds.2013-7312

DO - 10.3168/jds.2013-7312

M3 - Journal article

C2 - 24704225

VL - 97

SP - 3866

EP - 3877

JO - Journal of Dairy Science

JF - Journal of Dairy Science

SN - 0022-0302

IS - 6

ER -