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Nils Skajaa

Trends in Antibiotic Use in Danish, Finnish, Norwegian and Swedish Children

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

Standard

Trends in Antibiotic Use in Danish, Finnish, Norwegian and Swedish Children. / Skajaa, Nils; Gehrt, Lise; Nieminen, Heta et al.
I: Clinical epidemiology, Bind 14, 2022, s. 937-947.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

Harvard

Skajaa, N, Gehrt, L, Nieminen, H, Laake, I, Englund, H, Sönksen, UW, Feiring, B, Benn, CS, Trogstad, L, Palmu, AA & Sørup, S 2022, 'Trends in Antibiotic Use in Danish, Finnish, Norwegian and Swedish Children', Clinical epidemiology, bind 14, s. 937-947. https://doi.org/10.2147/CLEP.S362262

APA

Skajaa, N., Gehrt, L., Nieminen, H., Laake, I., Englund, H., Sönksen, U. W., Feiring, B., Benn, C. S., Trogstad, L., Palmu, A. A., & Sørup, S. (2022). Trends in Antibiotic Use in Danish, Finnish, Norwegian and Swedish Children. Clinical epidemiology, 14, 937-947. https://doi.org/10.2147/CLEP.S362262

CBE

Skajaa N, Gehrt L, Nieminen H, Laake I, Englund H, Sönksen UW, Feiring B, Benn CS, Trogstad L, Palmu AA, et al. 2022. Trends in Antibiotic Use in Danish, Finnish, Norwegian and Swedish Children. Clinical epidemiology. 14:937-947. https://doi.org/10.2147/CLEP.S362262

MLA

Skajaa, Nils et al. "Trends in Antibiotic Use in Danish, Finnish, Norwegian and Swedish Children". Clinical epidemiology. 2022, 14. 937-947. https://doi.org/10.2147/CLEP.S362262

Vancouver

Skajaa N, Gehrt L, Nieminen H, Laake I, Englund H, Sönksen UW et al. Trends in Antibiotic Use in Danish, Finnish, Norwegian and Swedish Children. Clinical epidemiology. 2022;14:937-947. doi: 10.2147/CLEP.S362262

Author

Skajaa, Nils ; Gehrt, Lise ; Nieminen, Heta et al. / Trends in Antibiotic Use in Danish, Finnish, Norwegian and Swedish Children. I: Clinical epidemiology. 2022 ; Bind 14. s. 937-947.

Bibtex

@article{3854faf0d1b1487a913b0d911450222d,
title = "Trends in Antibiotic Use in Danish, Finnish, Norwegian and Swedish Children",
abstract = "Objective: To compare the use of antibiotics in children in four Northern European countries.Methods: We conducted a register-based study based on individual-level prescription data from national prescription registers. We identified all redeemed outpatient prescriptions for systemic antibiotics in children aged 0-14 years from July 2006 to June 2017 in Denmark, Finland, Norway, and Sweden. We computed incidence rates and incidence rate ratios of treatment episodes with any antibiotic and different antibiotic classes.Results: In 2016/2017, the rates of antibiotic treatment episodes per 1000 person-years in children aged 0-14 years were 429, 284, 219, and 184 in Finland, Denmark, Sweden, and Norway, respectively, and the rate ratios (95% confidence intervals) compared with Norway were 2.33 (2.33-2.34), 1.54 (1.54-1.55), and 1.19 (1.19-1.20) in Finland, Denmark, and Sweden, respectively. The rate of antibiotic treatment episodes declined over time in all countries. The relative reductions in 2016/2017 compared with 2006/2007 were 36% in Finland, 40% in Denmark, 49% in Sweden, and 29% in Norway. Treatment episodes peaked between age 12 and 18 months. The most used antibiotic class was beta-lactamase sensitive penicillins among all children in Norway and Sweden and among children above two years in Denmark, while penicillins with extended spectrum were most used in Finland and among the youngest children in Denmark.Conclusion: In all countries, the use of antibiotics in children declined between 2006 and 2017. However, there were still considerable differences in antibiotic use between otherwise quite similar Nordic countries, with a more than 2-fold difference between the countries with the lowest and highest rates. Interventions to reduce the number of antibiotic treatment episodes in the countries with higher rates could reduce the total antibiotic use.",
author = "Nils Skajaa and Lise Gehrt and Heta Nieminen and Ida Laake and H{\'e}l{\`e}ne Englund and S{\"o}nksen, {Ute Wolff} and Berit Feiring and Benn, {Christine Stabell} and Lill Trogstad and Palmu, {Arto A} and Signe S{\o}rup",
year = "2022",
doi = "10.2147/CLEP.S362262",
language = "English",
volume = "14",
pages = "937--947",
journal = "Clinical epidemiology",
issn = "1179-1349",
publisher = "Dove Medical Press Ltd.",

}

RIS

TY - JOUR

T1 - Trends in Antibiotic Use in Danish, Finnish, Norwegian and Swedish Children

AU - Skajaa, Nils

AU - Gehrt, Lise

AU - Nieminen, Heta

AU - Laake, Ida

AU - Englund, Hélène

AU - Sönksen, Ute Wolff

AU - Feiring, Berit

AU - Benn, Christine Stabell

AU - Trogstad, Lill

AU - Palmu, Arto A

AU - Sørup, Signe

PY - 2022

Y1 - 2022

N2 - Objective: To compare the use of antibiotics in children in four Northern European countries.Methods: We conducted a register-based study based on individual-level prescription data from national prescription registers. We identified all redeemed outpatient prescriptions for systemic antibiotics in children aged 0-14 years from July 2006 to June 2017 in Denmark, Finland, Norway, and Sweden. We computed incidence rates and incidence rate ratios of treatment episodes with any antibiotic and different antibiotic classes.Results: In 2016/2017, the rates of antibiotic treatment episodes per 1000 person-years in children aged 0-14 years were 429, 284, 219, and 184 in Finland, Denmark, Sweden, and Norway, respectively, and the rate ratios (95% confidence intervals) compared with Norway were 2.33 (2.33-2.34), 1.54 (1.54-1.55), and 1.19 (1.19-1.20) in Finland, Denmark, and Sweden, respectively. The rate of antibiotic treatment episodes declined over time in all countries. The relative reductions in 2016/2017 compared with 2006/2007 were 36% in Finland, 40% in Denmark, 49% in Sweden, and 29% in Norway. Treatment episodes peaked between age 12 and 18 months. The most used antibiotic class was beta-lactamase sensitive penicillins among all children in Norway and Sweden and among children above two years in Denmark, while penicillins with extended spectrum were most used in Finland and among the youngest children in Denmark.Conclusion: In all countries, the use of antibiotics in children declined between 2006 and 2017. However, there were still considerable differences in antibiotic use between otherwise quite similar Nordic countries, with a more than 2-fold difference between the countries with the lowest and highest rates. Interventions to reduce the number of antibiotic treatment episodes in the countries with higher rates could reduce the total antibiotic use.

AB - Objective: To compare the use of antibiotics in children in four Northern European countries.Methods: We conducted a register-based study based on individual-level prescription data from national prescription registers. We identified all redeemed outpatient prescriptions for systemic antibiotics in children aged 0-14 years from July 2006 to June 2017 in Denmark, Finland, Norway, and Sweden. We computed incidence rates and incidence rate ratios of treatment episodes with any antibiotic and different antibiotic classes.Results: In 2016/2017, the rates of antibiotic treatment episodes per 1000 person-years in children aged 0-14 years were 429, 284, 219, and 184 in Finland, Denmark, Sweden, and Norway, respectively, and the rate ratios (95% confidence intervals) compared with Norway were 2.33 (2.33-2.34), 1.54 (1.54-1.55), and 1.19 (1.19-1.20) in Finland, Denmark, and Sweden, respectively. The rate of antibiotic treatment episodes declined over time in all countries. The relative reductions in 2016/2017 compared with 2006/2007 were 36% in Finland, 40% in Denmark, 49% in Sweden, and 29% in Norway. Treatment episodes peaked between age 12 and 18 months. The most used antibiotic class was beta-lactamase sensitive penicillins among all children in Norway and Sweden and among children above two years in Denmark, while penicillins with extended spectrum were most used in Finland and among the youngest children in Denmark.Conclusion: In all countries, the use of antibiotics in children declined between 2006 and 2017. However, there were still considerable differences in antibiotic use between otherwise quite similar Nordic countries, with a more than 2-fold difference between the countries with the lowest and highest rates. Interventions to reduce the number of antibiotic treatment episodes in the countries with higher rates could reduce the total antibiotic use.

U2 - 10.2147/CLEP.S362262

DO - 10.2147/CLEP.S362262

M3 - Journal article

C2 - 35966903

VL - 14

SP - 937

EP - 947

JO - Clinical epidemiology

JF - Clinical epidemiology

SN - 1179-1349

ER -