Mette Bjerre

Soluble form of membrane attack complex independently predicts mortality and cardiovascular events in patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  • Søren Lindberg
  • ,
  • Sune H Pedersen
  • ,
  • Rasmus Mogelvang
  • ,
  • Søren Galatius, Institut for Matematiske Fag, Danmark
  • Allan Flyvbjerg, Danmark
  • Jan Skov Jensen, Kirurgi og Intern Medicin, Danmark
  • Mette Bjerre
The complement system is an important mediator of inflammation, which plays a pivotal role in atherosclerosis and acute myocardial infarction (AMI). Animal studies suggest that activation of the complement cascade resulting in the formation of soluble membrane attack complex (sMAC), contributes to both atherosclerosis and plaque rupture and may be the direct cause of tissue damage related to ischemia/reperfusion injury. However clinical data of sMAC during an AMI is sparse. Accordingly the aim was to investigate the prognostic role of sMAC in patients with ST-segment elevation myocardial infarction (STEMI).
OriginalsprogEngelsk
TidsskriftAmerican Heart Journal
Vol/bind164
Nummer5
Sider (fra-til)786-92
Antal sider7
ISSN0002-8703
DOI
StatusUdgivet - 2012

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