Martin Hansen

Abiotic degradation of antibiotic ionophores.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Standard

Abiotic degradation of antibiotic ionophores. / Bohn, Pernille; Bak, Søren A; Björklund, Erland; Krogh, Kristine A; Hansen, Martin.

I: Environmental pollution (Barking, Essex : 1987), Bind 182, 01.11.2013, s. 177-183.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Bohn, P, Bak, SA, Björklund, E, Krogh, KA & Hansen, M 2013, 'Abiotic degradation of antibiotic ionophores.', Environmental pollution (Barking, Essex : 1987), bind 182, s. 177-183. <http://linkinghub.elsevier.com/retrieve/pii/S0269749113003643>

APA

Bohn, P., Bak, S. A., Björklund, E., Krogh, K. A., & Hansen, M. (2013). Abiotic degradation of antibiotic ionophores. Environmental pollution (Barking, Essex : 1987), 182, 177-183. http://linkinghub.elsevier.com/retrieve/pii/S0269749113003643

CBE

Bohn P, Bak SA, Björklund E, Krogh KA, Hansen M. 2013. Abiotic degradation of antibiotic ionophores. Environmental pollution (Barking, Essex : 1987). 182:177-183.

MLA

Bohn, Pernille o.a.. "Abiotic degradation of antibiotic ionophores.". Environmental pollution (Barking, Essex : 1987). 2013, 182. 177-183.

Vancouver

Bohn P, Bak SA, Björklund E, Krogh KA, Hansen M. Abiotic degradation of antibiotic ionophores. Environmental pollution (Barking, Essex : 1987). 2013 nov 1;182:177-183.

Author

Bohn, Pernille ; Bak, Søren A ; Björklund, Erland ; Krogh, Kristine A ; Hansen, Martin. / Abiotic degradation of antibiotic ionophores. I: Environmental pollution (Barking, Essex : 1987). 2013 ; Bind 182. s. 177-183.

Bibtex

@article{0038618d144f4509bd5f40376d4144c6,
title = "Abiotic degradation of antibiotic ionophores.",
abstract = "Hydrolytic and photolytic degradation were investigated for the ionophore antibiotics lasalocid, monensin, salinomycin, and narasin. The hydrolysis study was carried out by dissolving the ionophores in solutions of pH 4, 7, and 9, followed by incubation at three temperatures of 6, 22, and 28 °C for maximum 34 days. Using LC-MS/MS for chemical analysis, lasalocid was not found to hydrolyse in any of the tested environments. Monensin, salinomycin, and narasin were all stable in neutral or alkaline solution but hydrolysed in the solution with a pH of 4. Half-lives at 25 °C were calculated to be 13, 0.6, and 0.7 days for monensin, salinomycin, and narasin, respectively. Absorbance spectra from each compound indicated that only lasalocid is degraded by photolysis (half-life below 1 h) due to an absorbance maximum around 303 nm, and monensin, salinomycin, and narasin are resistant to direct photolysis because they absorb light of environmentally irrelevant wavelengths.",
author = "Pernille Bohn and Bak, {S{\o}ren A} and Erland Bj{\"o}rklund and Krogh, {Kristine A} and Martin Hansen",
year = "2013",
month = nov,
day = "1",
language = "English",
volume = "182",
pages = "177--183",
journal = "Environmental pollution (Barking, Essex : 1987)",

}

RIS

TY - JOUR

T1 - Abiotic degradation of antibiotic ionophores.

AU - Bohn, Pernille

AU - Bak, Søren A

AU - Björklund, Erland

AU - Krogh, Kristine A

AU - Hansen, Martin

PY - 2013/11/1

Y1 - 2013/11/1

N2 - Hydrolytic and photolytic degradation were investigated for the ionophore antibiotics lasalocid, monensin, salinomycin, and narasin. The hydrolysis study was carried out by dissolving the ionophores in solutions of pH 4, 7, and 9, followed by incubation at three temperatures of 6, 22, and 28 °C for maximum 34 days. Using LC-MS/MS for chemical analysis, lasalocid was not found to hydrolyse in any of the tested environments. Monensin, salinomycin, and narasin were all stable in neutral or alkaline solution but hydrolysed in the solution with a pH of 4. Half-lives at 25 °C were calculated to be 13, 0.6, and 0.7 days for monensin, salinomycin, and narasin, respectively. Absorbance spectra from each compound indicated that only lasalocid is degraded by photolysis (half-life below 1 h) due to an absorbance maximum around 303 nm, and monensin, salinomycin, and narasin are resistant to direct photolysis because they absorb light of environmentally irrelevant wavelengths.

AB - Hydrolytic and photolytic degradation were investigated for the ionophore antibiotics lasalocid, monensin, salinomycin, and narasin. The hydrolysis study was carried out by dissolving the ionophores in solutions of pH 4, 7, and 9, followed by incubation at three temperatures of 6, 22, and 28 °C for maximum 34 days. Using LC-MS/MS for chemical analysis, lasalocid was not found to hydrolyse in any of the tested environments. Monensin, salinomycin, and narasin were all stable in neutral or alkaline solution but hydrolysed in the solution with a pH of 4. Half-lives at 25 °C were calculated to be 13, 0.6, and 0.7 days for monensin, salinomycin, and narasin, respectively. Absorbance spectra from each compound indicated that only lasalocid is degraded by photolysis (half-life below 1 h) due to an absorbance maximum around 303 nm, and monensin, salinomycin, and narasin are resistant to direct photolysis because they absorb light of environmentally irrelevant wavelengths.

M3 - Journal article

VL - 182

SP - 177

EP - 183

JO - Environmental pollution (Barking, Essex : 1987)

JF - Environmental pollution (Barking, Essex : 1987)

ER -