Louise Hauge Matzen

Long-term Outcomes of Temporomandibular Joints in Juvenile Idiopathic Arthritis: 17 Years of Followup of a Nordic Juvenile Idiopathic Arthritis Cohort

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

DOI

  • Mia Glerup
  • Peter Stoustrup
  • Louise Hauge Matzen
  • Veronika Rypdal, Departments of Pediatrics, Dept. of Pediatrics, University Hospital of North Norway, Tromsø, Norway, Department of Clinical Medicine, Faculty of Health Sciences, UIT, The Arctic University of Norway, Tromsø, Norge
  • Ellen Nordal, Departments of Pediatrics, Dept. of Pediatrics, University Hospital of North Norway, Tromsø, Norway, Department of Clinical Medicine, Faculty of Health Sciences, UIT, The Arctic University of Norway, Tromsø, Norge
  • Paula Frid, Department of Clinical Medicine, Faculty of Health Sciences, UIT, The Arctic University of Norway, Tromsø, Department of Otorhinolaryngology and Department and Division of Oral and Maxillofacial Surgery, University Hospital North Norway and Public Dental Service Competence Center of North Norway, Tromsø, Norway, Norge
  • Ellen Dalen Arnstad, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU - Norwegian University of Science and Technology, Trondheim, Norway, Department of Pediatrics, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway., Norge
  • Marite Rygg, Department of Pediatrics, Dept. of Pediatrics, St. Olavs Hospital, Norway, Trondheim, Norway, Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU - Norwegian University of Science and Technology, Trondheim, Norway, Norge
  • Olafur Thorarensen, Dep. of oral and Craniomaxillofacial surgery, Dept. of oral and Craniomaxillofacial surgery, St. Olavs Hospital, Norway, NTNU, Trondheim, Norway, Norge
  • Maria Ekelund, Department of Pediatrics, Ryhov County Hospital, Jonkoping, Sweden., Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden., Sverige
  • Lillemor Berntson, Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden., Sverige
  • Anders Fasth, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Sweden, Sverige
  • Håkan Nilsson, Department of Oral and Maxillofacial Surgery, Dept. of Oral and Maxillofacial Surgery, The Institute for Postgraduate Dental Education, Jönköping, Sweden, Jonkoping, Sweden, Sverige
  • Suvi Peltoniemi, Hospital for Children and Adolescents, University of Helsinki, Finland, Helsinki, Finland
  • ,
  • Kristiina Aalto, Hospital for Children and Adolescents, University of Helsinki, Finland, Helsinki, Finland, Finland
  • Sirpa Arte, Orthodontics, Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Finland, Finland
  • Peter Toftedal, Department of Pediatrics, Dept. of Pediatrics, Copenhagen University Hospital, Denmark, Copenhagen, Denmark, Danmark
  • Susan Nielsen, Department of Pediatrics, Dept. of Pediatrics, Copenhagen University Hospital, Denmark, Copenhagen, Denmark,
  • Troels Herlin
  • Sven Kreiborg, Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Denmark, Danmark
  • Thomas Klit Pedersen

OBJECTIVE: To determine the prevalence of orofacial symptoms, dysfunctions, and deformities of the temporomandibular joint (TMJ) in juvenile idiopathic arthritis (JIA) 17 years after disease onset.

METHODS: Drawn from a prospective, population-based Nordic JIA cohort with disease onset from 1997 to 2000, 420 consecutive cases were eligible for orofacial evaluation of TMJ involvement. The followup visit included demographic data, a standardized clinical orofacial examination, and full-face cone-beam computed tomography (CBCT). For comparison, 200 age-matched healthy controls were used.

RESULTS: Of 420 eligible participants with JIA, 265 (63%) were included (mean age 23.5 ± 4.2 yrs) and completed a standardized clinical orofacial examination. Of these, 245 had a full-face CBCT performed. At least 1 orofacial symptom was reported by 33%. Compared to controls, the JIA group significantly more often reported TMJ pain, TMJ morning stiffness, and limitation on chewing. Further, among participants reporting complaints, the number of symptoms was also higher in JIA. The mean maximal incisal opening was lower in the JIA group (p < 0.001), and TMJ pain on palpation was more frequent. Condylar deformities and/or erosions were observed in 61% as assessed by CBCT, showing bilateral changes in about 70%. Risk factors of condylar deformities were orofacial dysfunction or biologic treatment; enthesitis-related arthritis was protective.

CONCLUSION: This study of the longterm consequences of TMJ involvement in a population-based JIA cohort reports persistence of comprehensive symptoms, dysfunctions, and damage of the TMJ into adulthood. We suggest interdisciplinary followup of JIA patients also in adulthood.

OriginalsprogEngelsk
Artikelnummer190231
TidsskriftJournal of Rheumatology
Vol/bind47
Nummer5
Sider (fra-til)730-738
Antal sider9
ISSN0315-162X
DOI
StatusUdgivet - 2020

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