Faecal incontinence affects 40% of patients with systemic sclerosis (SSc). Several factors, including impaired anal sphincter function, reduced rectoanal sensation, abnormal rectoanal wall properties, and fast gastrointestinal transit, can cause faecal incontinence. Internal anal sphincter function is reduced in some patients with SSc, but other factors causing faecal incontinence remain to be studied in detail. Our aim was to compare tests of colorectal and anal physiology in patients with SSc suffering from faecal incontinence to those of SSc patients without faecal incontinence and healthy controls.