Kelun Wang

Adjunctive effects of laser therapy on somatosensory function and vasomotor regulation of periodontal tissues in patients with periodontitis- A randomized controlled clinical trial

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DOI

  • Huiqing Gou, Jiangsu Key Laboratory of Oral Disease, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China., Kina
  • Ruyi Fan, Jiangsu Key Laboratory of Oral Disease, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China., Kina
  • Xu Chen, Jiangsu Key Laboratory of Oral Disease, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China., Department of Periodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China., Kina
  • Lu Li, Jiangsu Key Laboratory of Oral Disease, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China., Department of Periodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China., Kina
  • Xiaoqian Wang, Jiangsu Key Laboratory of Oral Disease, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China., Department of Periodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China., Kina
  • Yan Xu, Jiangsu Key Laboratory of Oral Disease, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China., Department of Periodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China., Kina
  • Peter Svensson
  • Kelun Wang

BACKGROUND: The purpose of this prospective study was to compare the changes in periodontal somatosensory function and microcirculation in patients with periodontitis following initial treatment with scaling and root planing (SRP) with or without adjuvant laser therapy.

METHODS: Twenty-four patients suffering from periodontitis were recruited and randomly allocated into a split-mouth design to either SRP combined laser therapy side (test side) or SRP only side (control side). All treatments were performed by the same investigator at a single visit. Laser Doppler Flowmetry (LDF) and Quantitative Sensory Testing (QST) were performed at baseline (W0), 1 week (1W), 2 weeks (2W), and 4 weeks (4W) after treatment on both sides of the attached gingiva of the maxillary lateral incisor. Clinical examination including pocket probing depth (PPD) and bleeding on probing (BOP) was performed at W0, 2W, and 4W on both sides. Data were analyzed with two-way analysis of variance (ANOVA).

RESULTS: The PPD and BOP significantly improved after treatment (P <0.001). The LDF values were significantly decreased on both sides at all follow-up time points (P <0.001), temperature was increased only on the test side (P = 0.017) whereas there was no significant change on the control side (P = 0.792). Significantly less sensitivity was observed for all QST parameters (P <0.030) except for warmth detection after treatment.

CONCLUSION: Adjunctive use of laser therapy did not provide any significant clinically advantage or additional effects on the recovery of periodontal somatosensory function or gingival microcirculation in the present study. This article is protected by copyright. All rights reserved.

OriginalsprogEngelsk
TidsskriftJournal of Periodontology
Vol/bind91
Nummer10
Sider (fra-til)1307-1317
Antal sider11
ISSN0022-3492
DOI
StatusUdgivet - okt. 2020

Bibliografisk note

Funding Information:
This investigation was funded by the National Natural Science Foundation of China (81771074) and from A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD, 2018-87). We would like to thank the Orofacial Pain and TMD Research Unit, Institute of Stomatology, Affiliated Hospital of Stomatology, Nanjing Medical University, for their support. The authors report no conflicts of interest related to this study.

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