Katrine J Emmertsen

International Validation of the Low Anterior Resection Syndrome Score

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Standard

International Validation of the Low Anterior Resection Syndrome Score. / Juul, Therese; Ahlberg, Madelene; Biondo, Sebastiano; Emmertsen, Katrine Jøssing; Espin, Eloy; Jimenez, Luis Miguel; Matzel, Klaus E; Palmer, Gabriella; Sauermann, Anna; Trenti, Loris; Zhang, Wei; Laurberg, Søren; Christensen, Peter.

I: Annals of Surgery, 17.04.2013.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Juul, T, Ahlberg, M, Biondo, S, Emmertsen, KJ, Espin, E, Jimenez, LM, Matzel, KE, Palmer, G, Sauermann, A, Trenti, L, Zhang, W, Laurberg, S & Christensen, P 2013, 'International Validation of the Low Anterior Resection Syndrome Score', Annals of Surgery. https://doi.org/10.1097/SLA.0b013e31828fac0b

APA

Juul, T., Ahlberg, M., Biondo, S., Emmertsen, K. J., Espin, E., Jimenez, L. M., Matzel, K. E., Palmer, G., Sauermann, A., Trenti, L., Zhang, W., Laurberg, S., & Christensen, P. (2013). International Validation of the Low Anterior Resection Syndrome Score. Annals of Surgery. https://doi.org/10.1097/SLA.0b013e31828fac0b

CBE

Juul T, Ahlberg M, Biondo S, Emmertsen KJ, Espin E, Jimenez LM, Matzel KE, Palmer G, Sauermann A, Trenti L, Zhang W, Laurberg S, Christensen P. 2013. International Validation of the Low Anterior Resection Syndrome Score. Annals of Surgery. https://doi.org/10.1097/SLA.0b013e31828fac0b

MLA

Vancouver

Author

Juul, Therese ; Ahlberg, Madelene ; Biondo, Sebastiano ; Emmertsen, Katrine Jøssing ; Espin, Eloy ; Jimenez, Luis Miguel ; Matzel, Klaus E ; Palmer, Gabriella ; Sauermann, Anna ; Trenti, Loris ; Zhang, Wei ; Laurberg, Søren ; Christensen, Peter. / International Validation of the Low Anterior Resection Syndrome Score. I: Annals of Surgery. 2013.

Bibtex

@article{c32762690f90453fbac098bdc7f5b549,
title = "International Validation of the Low Anterior Resection Syndrome Score",
abstract = "OBJECTIVE:: The aims of this study were to investigate the convergent and discriminative validity and reliability of the low anterior resection syndrome (LARS) score in an international setting. BACKGROUND:: The LARS score is a simple self-administered questionnaire measuring bowel dysfunction after rectal cancer surgery. The score is intended to be commonly used in international research and clinical practice in the future. Therefore, a thorough validation in an international setting is of utmost importance. METHODS:: The LARS score was translated using methods in keeping with current international recommendations. A total of 801 patients operated for rectal cancer in Sweden, Spain, Germany, and Denmark completed the LARS score questionnaire, including an anchor question assessing the impact of bowel function on quality of life. A subgroup of 218 patients completed the LARS score twice. Data were analyzed per country. RESULTS:: The LARS score has demonstrated a high convergent validity in terms of a high correlation between LARS score and quality of life (P <0.001). Sensitivity ranged from 67.7% to 88.3% and specificity from 58.1% to 86.3%. The LARS score was able to discriminate between groups of patients differing with regard to radiotherapy, surgery, and age (P <0.05). The score also demonstrated high reliability at test-retest with narrow limits of agreement and no statistically significant difference between scores at the first and second test. CONCLUSIONS:: The Swedish, Spanish, German, and Danish versions of the LARS score have proven to be valid and reliable tools for measuring LARS in European rectal cancer patients.",
author = "Therese Juul and Madelene Ahlberg and Sebastiano Biondo and Emmertsen, {Katrine J{\o}ssing} and Eloy Espin and Jimenez, {Luis Miguel} and Matzel, {Klaus E} and Gabriella Palmer and Anna Sauermann and Loris Trenti and Wei Zhang and S{\o}ren Laurberg and Peter Christensen",
year = "2013",
month = apr,
day = "17",
doi = "10.1097/SLA.0b013e31828fac0b",
language = "English",
journal = "Annals of Surgery",
issn = "0003-4932",
publisher = "LIPPINCOTT WILLIAMS & WILKINS",

}

RIS

TY - JOUR

T1 - International Validation of the Low Anterior Resection Syndrome Score

AU - Juul, Therese

AU - Ahlberg, Madelene

AU - Biondo, Sebastiano

AU - Emmertsen, Katrine Jøssing

AU - Espin, Eloy

AU - Jimenez, Luis Miguel

AU - Matzel, Klaus E

AU - Palmer, Gabriella

AU - Sauermann, Anna

AU - Trenti, Loris

AU - Zhang, Wei

AU - Laurberg, Søren

AU - Christensen, Peter

PY - 2013/4/17

Y1 - 2013/4/17

N2 - OBJECTIVE:: The aims of this study were to investigate the convergent and discriminative validity and reliability of the low anterior resection syndrome (LARS) score in an international setting. BACKGROUND:: The LARS score is a simple self-administered questionnaire measuring bowel dysfunction after rectal cancer surgery. The score is intended to be commonly used in international research and clinical practice in the future. Therefore, a thorough validation in an international setting is of utmost importance. METHODS:: The LARS score was translated using methods in keeping with current international recommendations. A total of 801 patients operated for rectal cancer in Sweden, Spain, Germany, and Denmark completed the LARS score questionnaire, including an anchor question assessing the impact of bowel function on quality of life. A subgroup of 218 patients completed the LARS score twice. Data were analyzed per country. RESULTS:: The LARS score has demonstrated a high convergent validity in terms of a high correlation between LARS score and quality of life (P <0.001). Sensitivity ranged from 67.7% to 88.3% and specificity from 58.1% to 86.3%. The LARS score was able to discriminate between groups of patients differing with regard to radiotherapy, surgery, and age (P <0.05). The score also demonstrated high reliability at test-retest with narrow limits of agreement and no statistically significant difference between scores at the first and second test. CONCLUSIONS:: The Swedish, Spanish, German, and Danish versions of the LARS score have proven to be valid and reliable tools for measuring LARS in European rectal cancer patients.

AB - OBJECTIVE:: The aims of this study were to investigate the convergent and discriminative validity and reliability of the low anterior resection syndrome (LARS) score in an international setting. BACKGROUND:: The LARS score is a simple self-administered questionnaire measuring bowel dysfunction after rectal cancer surgery. The score is intended to be commonly used in international research and clinical practice in the future. Therefore, a thorough validation in an international setting is of utmost importance. METHODS:: The LARS score was translated using methods in keeping with current international recommendations. A total of 801 patients operated for rectal cancer in Sweden, Spain, Germany, and Denmark completed the LARS score questionnaire, including an anchor question assessing the impact of bowel function on quality of life. A subgroup of 218 patients completed the LARS score twice. Data were analyzed per country. RESULTS:: The LARS score has demonstrated a high convergent validity in terms of a high correlation between LARS score and quality of life (P <0.001). Sensitivity ranged from 67.7% to 88.3% and specificity from 58.1% to 86.3%. The LARS score was able to discriminate between groups of patients differing with regard to radiotherapy, surgery, and age (P <0.05). The score also demonstrated high reliability at test-retest with narrow limits of agreement and no statistically significant difference between scores at the first and second test. CONCLUSIONS:: The Swedish, Spanish, German, and Danish versions of the LARS score have proven to be valid and reliable tools for measuring LARS in European rectal cancer patients.

U2 - 10.1097/SLA.0b013e31828fac0b

DO - 10.1097/SLA.0b013e31828fac0b

M3 - Journal article

C2 - 23598379

JO - Annals of Surgery

JF - Annals of Surgery

SN - 0003-4932

ER -