Katrine J Emmertsen

Bowel dysfunction after treatment for rectal cancer

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Bowel dysfunction after treatment for rectal cancer. / Emmertsen, Katrine; Laurberg, Søren.

I: Acta Odontologica Scandinavica, Bind 47, Nr. 6, 2008, s. 994-1003.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

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Emmertsen, Katrine ; Laurberg, Søren. / Bowel dysfunction after treatment for rectal cancer. I: Acta Odontologica Scandinavica. 2008 ; Bind 47, Nr. 6. s. 994-1003.

Bibtex

@article{81144f70fe9f11dda987000ea68e967b,
title = "Bowel dysfunction after treatment for rectal cancer",
abstract = "INTRODUCTION: Rectal cancer is a common disease in Western populations. Improved treatment modalities have resulted in increased survival and tumour control. With increasing survival there is a growing need for knowledge about the long-term side effects and functional results after the treatment. AIM: To describe the long-term functional outcome in patients treated for rectal cancer through a systematic review of the current literature and to provide an outline of the promising developments within this area. RESULTS: Standard resectional surgery with loss of the rectal reservoir function results in poor functional results in up to 50-60% of the patients. New methods of surgery including the construction of a neoreservoir and improvement of the technique for local excision have been developed to minimize the functional disturbances without compromising the oncological result. The addition of chemo and/or radiotherapy approximately doubles the risk of poor functional results. During the last decades the techniques for chemo/radiotherapy has been markedly improved with a positive impact on functional outcome. New methods for treatment of functional disturbances e.g. bowel irrigation and sacral nerve stimulation are currently under development. PERSPECTIVES: To improve the functional outcome in this growing patient population several approaches can be taken. The primary cancer treatment must be improved by minimizing the surgical trauma and optimizing the imaging and radiation techniques. Population screening should be considered in order to find the cancers at an earlier stage, hereby increasing the proportion of patients eligible for local excision without the need for chemo/irradiation. All patients recovering from rectal resection should be examined and registered systematically regarding their functional results and treatment should be offered to the severely affected patients. More studies are still needed to evaluate the efficacy of irrigation and nerve stimulation in this patient group.",
keywords = "Anastomosis, Surgical, Chemotherapy, Adjuvant, Chronic Disease, Colon, Colonic Pouches, Colostomy, Digestive System Surgical Procedures, Fecal Incontinence, Humans, Irrigation, Neoadjuvant Therapy, Radiotherapy, Adjuvant, Rectal Neoplasms, Rectum, Time Factors, Transcutaneous Electric Nerve Stimulation",
author = "Katrine Emmertsen and S{\o}ren Laurberg",
year = "2008",
doi = "10.1080/02841860802195251",
language = "English",
volume = "47",
pages = "994--1003",
journal = "Acta Odontologica Scandinavica",
issn = "0001-6357",
publisher = "Taylor & Francis ",
number = "6",

}

RIS

TY - JOUR

T1 - Bowel dysfunction after treatment for rectal cancer

AU - Emmertsen, Katrine

AU - Laurberg, Søren

PY - 2008

Y1 - 2008

N2 - INTRODUCTION: Rectal cancer is a common disease in Western populations. Improved treatment modalities have resulted in increased survival and tumour control. With increasing survival there is a growing need for knowledge about the long-term side effects and functional results after the treatment. AIM: To describe the long-term functional outcome in patients treated for rectal cancer through a systematic review of the current literature and to provide an outline of the promising developments within this area. RESULTS: Standard resectional surgery with loss of the rectal reservoir function results in poor functional results in up to 50-60% of the patients. New methods of surgery including the construction of a neoreservoir and improvement of the technique for local excision have been developed to minimize the functional disturbances without compromising the oncological result. The addition of chemo and/or radiotherapy approximately doubles the risk of poor functional results. During the last decades the techniques for chemo/radiotherapy has been markedly improved with a positive impact on functional outcome. New methods for treatment of functional disturbances e.g. bowel irrigation and sacral nerve stimulation are currently under development. PERSPECTIVES: To improve the functional outcome in this growing patient population several approaches can be taken. The primary cancer treatment must be improved by minimizing the surgical trauma and optimizing the imaging and radiation techniques. Population screening should be considered in order to find the cancers at an earlier stage, hereby increasing the proportion of patients eligible for local excision without the need for chemo/irradiation. All patients recovering from rectal resection should be examined and registered systematically regarding their functional results and treatment should be offered to the severely affected patients. More studies are still needed to evaluate the efficacy of irrigation and nerve stimulation in this patient group.

AB - INTRODUCTION: Rectal cancer is a common disease in Western populations. Improved treatment modalities have resulted in increased survival and tumour control. With increasing survival there is a growing need for knowledge about the long-term side effects and functional results after the treatment. AIM: To describe the long-term functional outcome in patients treated for rectal cancer through a systematic review of the current literature and to provide an outline of the promising developments within this area. RESULTS: Standard resectional surgery with loss of the rectal reservoir function results in poor functional results in up to 50-60% of the patients. New methods of surgery including the construction of a neoreservoir and improvement of the technique for local excision have been developed to minimize the functional disturbances without compromising the oncological result. The addition of chemo and/or radiotherapy approximately doubles the risk of poor functional results. During the last decades the techniques for chemo/radiotherapy has been markedly improved with a positive impact on functional outcome. New methods for treatment of functional disturbances e.g. bowel irrigation and sacral nerve stimulation are currently under development. PERSPECTIVES: To improve the functional outcome in this growing patient population several approaches can be taken. The primary cancer treatment must be improved by minimizing the surgical trauma and optimizing the imaging and radiation techniques. Population screening should be considered in order to find the cancers at an earlier stage, hereby increasing the proportion of patients eligible for local excision without the need for chemo/irradiation. All patients recovering from rectal resection should be examined and registered systematically regarding their functional results and treatment should be offered to the severely affected patients. More studies are still needed to evaluate the efficacy of irrigation and nerve stimulation in this patient group.

KW - Anastomosis, Surgical

KW - Chemotherapy, Adjuvant

KW - Chronic Disease

KW - Colon

KW - Colonic Pouches

KW - Colostomy

KW - Digestive System Surgical Procedures

KW - Fecal Incontinence

KW - Humans

KW - Irrigation

KW - Neoadjuvant Therapy

KW - Radiotherapy, Adjuvant

KW - Rectal Neoplasms

KW - Rectum

KW - Time Factors

KW - Transcutaneous Electric Nerve Stimulation

U2 - 10.1080/02841860802195251

DO - 10.1080/02841860802195251

M3 - Journal article

C2 - 18607875

VL - 47

SP - 994

EP - 1003

JO - Acta Odontologica Scandinavica

JF - Acta Odontologica Scandinavica

SN - 0001-6357

IS - 6

ER -