Kamille Smidt Rasmussen

Ph.d., Lektor, FP-leder

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Kamille Smidt

Lektor, FP-leder

  • Institut for Klinisk Medicin - Staben, Institut for Klinisk Medicin
Palle Juul-Jensens Boulevard 82
A, INCUBA Skejby, A.117
Aarhus N

E-mail: kamille@clin.au.dk

Telefon: +4593508407


The zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells

Maxel, T., Smidt, K., Petersen, C. C., Honoré, B., Christensen, A. K., Jeppesen, P. B., Brock, B., Rungby, J., Palmfeldt, J. & Larsen, A., 13 jun. 2019, I: Scientific Reports. 9, 1, 15 s., 8589.

Expression Patterns and Correlations with Metabolic Markers of Zinc Transporters ZIP14 and ZNT1 in Obesity and Polycystic Ovary Syndrome

Maxel, T., Svendsen, P. F., Smidt, K., Lauridsen, J. K., Brock, B., Pedersen, S. B., Rungby, J. & Larsen, A., 2017, I: Frontiers in Endocrinology. 8, 11 s., 38.

The zinc transporter ZNT3 co-localizes with insulin in INS-1E pancreatic beta cells and influences cell survival, insulin secretion capacity, and ZNT8 expression

Smidt, K., Larsen, A., Brønden, A., Sørensen, K. S., Nielsen, J. V., Praetorius, J., Martensen, P. M. & Rungby, J., 11 feb. 2016, I: BioMetals. 29, 2, s. 287–298 12 s.

Obesity and age-related alterations in the gene expression of zinc-transporter proteins in the human brain

Olesen, R. H., Hyde, T. M., Kleinman, J. E., Smidt, K., Rungby, J. & Larsen, A., 2016, I: Translational Psychiatry. 6, 6, s. e838

Exogenous Metallothionein Potentiates the Insulin Response at Normal Glucose Concentrations in INS-1E Beta Cells without disturbing Intracellular ZnT8 Expression

Nygaard, S. B., Lund, N. S., Larsen, A., Pedersen, N., Rungby, J. & Smidt, K., feb. 2015, I: Basic & Clinical Pharmacology & Toxicology. 116, 2, s. 173-177 5 s.

Dysregulation of Zinc and Iron Balance in Adipose Tissue from Diabetic Sand Rats (Psammomys obesus)

Juul, T. M., Pold, R., Larsen, A., Pedersen, S. B., Carlson, D., Rolin, B., Bödvarsdóttir, T. B., Lund, S., Rungby, J. & Rasmussen, K. S., 2015, I: Journal of Diabetes & Metabolism. 6/2

Gene expression of the zinc transporter ZIP14 (SLC39a14) is affected by weight loss and metabolic status and associates with PPARγ in human adipose tissue and 3T3-L1 pre-adipocytes

Juul, T. M., Smidt, K., Larsen, A., Bennetzen, M., Cullberg, K., Fjeldborg, K., Lund, S., Pedersen, S. B. & Rungby, J., 2015, I: Obesity. 2, 11 s., 46.

Effects of zinc supplementation and zinc chelation on in vitro β-cell function in INS-1E cells

Nygaard, S. B., Larsen, A., Knuhtsen, A., Rungby, J. & Smidt, K., 2014, I: BMC Research Notes. 7, s. 84

Influence of GLP-1 on Myocardial Glucose Metabolism in Healthy Men during Normo- or Hypoglycemia

Gejl, M., Lerche, S., Mengel, A., Møller, N., Bibby, B. M., Smidt, K., Brock, B., Søndergaard, H., Bøtker, H. E., Gjedde, A., Holst, J. J., Hansen, S. B. & Rungby, J., 2014, I: PLOS ONE. 9, 1, s. e83758

The influence of Endothelium on Smooth Muscle-derived alpha-1-integrin, ROS and Collagen IV expression. Effects of High Glucose and Diabetes

Ledet, T., Mumm, B. H. & Smidt, K., 2014, I: Arteriosclerosis, Thrombosis, and Vascular Biology.

The single-dose pharmacokinetics of Alitretinoin and its metabolites are not significantly altered in patients with cirrhosis

Thyssen, J., Vester, L., Grønhøj Larsen, C., Smidt, K., Jakobsen, P., Hansen, S. H., Vind-Kezunovic, D., Gluud, L. L. & Larsen, F. G., 2 aug. 2013, I: British Journal of Dermatology.

Metallic gold beads in hyaluronic acid: a novel form of gold-based immunosuppression? Investigations of the immunosuppressive effects of metallic gold on cultured J774 macrophages and on neuronal gene expression in experimental autoimmune encephalomyelitis

Pedersen, D. S., Tran, T. P., Smidt, K., Bibby, B. M., Rungby, J. & Larsen, A., jun. 2013, I: BioMetals. 26, 3, s. 369-85 17 s.

Insulin secretion and ZnT8 gene expression are decreased by ZnT3 overexpression

Smidt, K., Sørensen, K. S., Larsen, A., Praetorius, J., Martensen, P. M. & Rungby, J., 2013, I: Diabetologia. 56, s199

Zinc buffering by exogenous Zn7-metallothionein-2A affects insulin production, insulin secretion and intracellular zinc regulation in beta cells.

Nygaard, S. B., Pedersen, N. K., Larsen, A., Rungby, J. & Smidt, K., 2013, I: Diabetologia. 56, s199

ZnT3: a zinc transporter active in several organs

Smidt, K. & Rungby, J., feb. 2012, I: BioMetals. 25, 1, s. 1-8 8 s.

Measurement of free GH and bioactive IGF-I in non-diabetic haemodialysis patients treated with GH for 7 days

Frystyk, J., Djurhuus, C. B., Johansen, T., Lange, M., Smidt, K. & Christiansen, J. S., 2012, I: Nephrology, Dialysis, Transplantation. 27, 11, s. 4211-8 8 s.

siRNA-mediated knock-down of ZnT3 and ZnT8 affects production and secretion of insulin and apoptosis in INS-1E cells

Petersen, A. B., Smidt, K., Magnusson, N. E., Moore, F., Egefjord, L. & Rungby, J., 1 feb. 2011, I: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 119, 2, s. 93-102 10 s.

Cyclosporin and tacrolimus impair insulin secretion and transcriptional regulation in INS-1E beta-cells

Øzbay, A., Smidt, K., Mortensen, D. M., Carstens, J., Jørgensen, K. A. & Rungby, J., jan. 2011, I: British Journal of Pharmacology. 162, 1, s. 136-46 11 s.

Down-regulation of zinc transporters during terminal differentiation phase of 3T3-L1 preadipocytes.

Juul, T. M., Cullberg, K. B., Pedersen, S. B., Rungby, J. & Smidt, K., 2011, I: Basic & Clinical Pharmacology & Toxicology.

Effect of metallothioneins on glucose- and palmitate induced insulin secretion in mouse pancreatic islets

Pedersen, N. K., Nyegaard, S. B., Rungby, J. & Smidt, K., 2011, I: Basic & Clinical Pharmacology & Toxicology.

Targeting amyloid-beta by glucagon-like peptide -1 (GLP-1) in Alzheimer's disease and diabetes

Bak, A. M., Egefjord, L., Jensen, M. G., Steffensen, C., Stecher, C. W., Smidt, K., Brock, B. & Rungby, J., 2011, I: Expert Opinion On Therapeutic Targets. 15, 10, s. 1153-62 10 s.

Uptake of silver from metallic silver surfaces induces cell death and a pro-inflammatory response in cultured J774 macrophages

Locht, L. J., Smidt, K., Rungby, J., Stoltenberg, M. & Larsen, A., 2011, I: Histology and Histopathology. 26, 6

SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress

Smidt, K., Jessen, N., Petersen, A. B., Larsen, A., Magnusson, N., Jeppesen, J. B., Stoltenberg, M., Culvenor, J. G., Tsatsanis, A., Brock, B., Schmitz, O., Wogensen, L., Bush, A. I. & Rungby, J., 2009, I: P L o S One. 4, 5, s. e5684

Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?

Egefjord, L., Jensen, J., Bang-Berthelsen, C., Petersen, A. B., Smidt, K., Schmitz, O., Karlsen, A. E., Pociot, F., Chimienti, F., Rungby, J. & Magnusson, N., 2009, I: B M C Endocrine Disorders. 9, 1, s. 7

Zinc transporters in the pathophysiology of diabetes

Smidt, K., 2009, Aarhus Universitet.

Glucose and zinc-depletion stimulate beta cell expression of ZnT3, a zinc transporter, whereas ZnT3 KO mice have decreased beta cell capacity

Jeppesen, J. B., Larsen, A., Jessen, N., Magnusson, N., Egefjord, L., Wogensen, L., B., B., Schmitz, O., K., S., Stoltenberg, M. & J., R., 2008, I: Diabetologia. 50, Suppl. 1, s. S207 1 s.

Amyloid plaques arise from zinc-enriched cortical layers in APP/PS1 transgenic mice and are paradoxically enlarged with dietary zinc deficiency

Stoltenberg, M., Bush, AI., Jensen, G. B., Smidt, K., Larsen, A., Rungby, J., Lund, S., Jensen, P. D. & Danscher, G., 2007, I: Neuroscience. 150, s. 357-69

Zinc-transporter genes in human visceral and subcutaneous adipocytes: lean versus obese

Smidt, K., Pedersen, S. B., Brock, B., Schmitz, O., Fisker, S., Bendix, J., Wogensen, L. & Rungby, J., 2007, I: Molecular and Cellular Endocrinology. 264(1-2), s. 68-73 6 s.

Real-time PCR: Housekeeping Genes in the INS-1E Beta-cell Line

Smidt, K., Wogensen, L., Brock, B., Schmitz, O. & Rungby, J., 2006, I: Horm. Metab. Res.. 38, (1), s. 8-11 4 s.

Real-timePCR: Housekeepings genes in the INS-1E β-cell Line

K., S., Wogensen, L., B., B., O., S. & J., R., 2006, I: Horm. Metab. Res.. 38, s. 8-11 4 s.

Tomosyn is expressed in beta-cells and negatively regulates insulin exocytosis

Zhang, W., Lilja, L., Mandic, SA., Gromada, J., Smidt, K., Jansson, J., Takai, Y., Bark, C., Berggren, PO. & Meister, B., 2006, I: Diabetes. 55, 3

Long-term parathyroid- and c-cell function after radioiodine for benign thyroid diseases

Mortensen, L. S., Smidt, K., Jørgensen, A., Nielsen, J. T., Laurberg, P., Søndergaard, L., Rungby, J. & Theil, J., jul. 2005, I: Basic & Clinical Pharmacology & Toxicology. 97, 1, s. 22-8 7 s.

Long-term parathyroid- and C-cell function after radioiodine for benign thyroid diseases

Mortensen, L. S., Smidt, K., Jørgensen, A., Nielsen, J. T., Laurberg, P., LG, S. & Rungby, J., 2005, I: Basic & Clinical Pharmacology & Toxicology. 97, s. 22-8 7 s.

Neuronal calcium sensor-1 potentiates glucose-dependent exocytosis in pancreatic beta cells through activation of phosphatidylinositol 4-kinase beta

Gromada, J., Bark, C., Smidt, K., Efanov, A. M., Janson, J., Mandic, S. A., Webb, D-L., Zhang, W., Meister, B., Jeromin, A. & Berggren, P-O., 2005, I: Proceedings of the National Academy of Sciences of the United States of America. 102, 29, s. 10303-8 6 s.

Zinc fluxes during acute and chronic exposure of INS-1E cells to increasing glucose levels

Sondergaard, LG., Brock, B., Stoltenberg, M., Flyvbjerg, A., Schmitz, O., Smidt, K., Danscher, G. & Rungby, J., 2005, I: Horm. Metab. Res.. 37, s. 133-139

A nine-nucleotide deletion and splice variation in the coding region of the interferon induced ISG12 gene

Smidt, K. C. J., Hansen, L. L., Søgaard, T. M. M., Petersen, L. K., Knudsen, U. B. & Martensen, P. M., 30 jul. 2003, I: B B A - Proteins and Proteomics. 1638, 3, s. 227-34 8 s.

A nine-nucleotide deletion and splice variation in the coding region of the interferon induced ISG12 gene

Smidt, K., Hansen, L. L., Søgaard, T. M. M., Petersen, L. K., Knudsen, U. B. & Martensen, P. M., 30 jul. 2003, I: BBA General Subjects. 1636, 3, s. 227-234 8 s.