Institut for Biomedicin

Julie Werenberg Dreier

Birth characteristics and risk of febrile seizures

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Standard

Birth characteristics and risk of febrile seizures. / Christensen, Kirstine J.; Dreier, Julie W.; Skotte, Line; Feenstra, Bjarke; Grove, Jakob; Børglum, Anders; Mitrovic, Mitja; Cotsapas, Chris; Christensen, Jakob.

I: Acta Neurologica Scandinavica, Bind 144, Nr. 1, 07.2021, s. 51-57.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Christensen, KJ, Dreier, JW, Skotte, L, Feenstra, B, Grove, J, Børglum, A, Mitrovic, M, Cotsapas, C & Christensen, J 2021, 'Birth characteristics and risk of febrile seizures', Acta Neurologica Scandinavica, bind 144, nr. 1, s. 51-57. https://doi.org/10.1111/ane.13420

APA

Christensen, K. J., Dreier, J. W., Skotte, L., Feenstra, B., Grove, J., Børglum, A., Mitrovic, M., Cotsapas, C., & Christensen, J. (2021). Birth characteristics and risk of febrile seizures. Acta Neurologica Scandinavica, 144(1), 51-57. https://doi.org/10.1111/ane.13420

CBE

Christensen KJ, Dreier JW, Skotte L, Feenstra B, Grove J, Børglum A, Mitrovic M, Cotsapas C, Christensen J. 2021. Birth characteristics and risk of febrile seizures. Acta Neurologica Scandinavica. 144(1):51-57. https://doi.org/10.1111/ane.13420

MLA

Christensen, Kirstine J. o.a.. "Birth characteristics and risk of febrile seizures". Acta Neurologica Scandinavica. 2021, 144(1). 51-57. https://doi.org/10.1111/ane.13420

Vancouver

Christensen KJ, Dreier JW, Skotte L, Feenstra B, Grove J, Børglum A o.a. Birth characteristics and risk of febrile seizures. Acta Neurologica Scandinavica. 2021 jul;144(1):51-57. https://doi.org/10.1111/ane.13420

Author

Christensen, Kirstine J. ; Dreier, Julie W. ; Skotte, Line ; Feenstra, Bjarke ; Grove, Jakob ; Børglum, Anders ; Mitrovic, Mitja ; Cotsapas, Chris ; Christensen, Jakob. / Birth characteristics and risk of febrile seizures. I: Acta Neurologica Scandinavica. 2021 ; Bind 144, Nr. 1. s. 51-57.

Bibtex

@article{25c92761b5a04c479c8705ab85d7f0c6,
title = "Birth characteristics and risk of febrile seizures",
abstract = "Objective: Febrile seizure is a common childhood disorder that affects 2–5% of all children, and is associated with later development of epilepsy and psychiatric disorders. This study determines how the incidence of febrile seizures correlates with birth characteristics, age, sex and brain development. Methods: This is a cohort study of all children born Denmark between 1977 and 2011 who were alive at 3 months of age (N = 2,103,232). The Danish National Patient Register was used to identify children with febrile seizures up to 5 years of age. Follow-up ended on 31 December 2016 when all cohort members had potentially reached 5 years of age. Results: In total, 75,593 (3.59%, 95% CI: 3.57–3.62%) were diagnosed with febrile seizures. Incidence peaked at 16.7 months of age (median: 16.7 months, interquartile range: 12.5–24.0). The 5-year cumulative incidence of febrile seizures increased with decreasing birth weight (<1500 g; 5.42% (95% CI: 4.98–5.88% vs. 3,000–4,000 g; 3.53% (95% CI: 3.50–3.56%)) and with decreasing gestational age at birth (31–32 weeks; 5.90% (95% CI: 5.40–6.44%) vs. 39–40 weeks; 3.56% (95% CI: 3.53–3.60)). Lower gestational age at birth was associated with higher age at onset of a first febrile seizure; an association that essentially disappeared when correcting for age from conception. Conclusions: The risk of febrile seizures increased with decreasing birth weight and gestational age at birth. The association between low gestational age at birth and age at first febrile seizure suggests that onset of febrile seizures is associated with the stage of brain development.",
keywords = "birth weight, brain development, febrile seizures and epilepsy, gestational age",
author = "Christensen, {Kirstine J.} and Dreier, {Julie W.} and Line Skotte and Bjarke Feenstra and Jakob Grove and Anders B{\o}rglum and Mitja Mitrovic and Chris Cotsapas and Jakob Christensen",
note = "Publisher Copyright: {\textcopyright} 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
month = jul,
doi = "10.1111/ane.13420",
language = "English",
volume = "144",
pages = "51--57",
journal = "Acta Neurologica Scandinavica",
issn = "0001-6314",
publisher = "Wiley-Blackwell Munksgaard",
number = "1",

}

RIS

TY - JOUR

T1 - Birth characteristics and risk of febrile seizures

AU - Christensen, Kirstine J.

AU - Dreier, Julie W.

AU - Skotte, Line

AU - Feenstra, Bjarke

AU - Grove, Jakob

AU - Børglum, Anders

AU - Mitrovic, Mitja

AU - Cotsapas, Chris

AU - Christensen, Jakob

N1 - Publisher Copyright: © 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/7

Y1 - 2021/7

N2 - Objective: Febrile seizure is a common childhood disorder that affects 2–5% of all children, and is associated with later development of epilepsy and psychiatric disorders. This study determines how the incidence of febrile seizures correlates with birth characteristics, age, sex and brain development. Methods: This is a cohort study of all children born Denmark between 1977 and 2011 who were alive at 3 months of age (N = 2,103,232). The Danish National Patient Register was used to identify children with febrile seizures up to 5 years of age. Follow-up ended on 31 December 2016 when all cohort members had potentially reached 5 years of age. Results: In total, 75,593 (3.59%, 95% CI: 3.57–3.62%) were diagnosed with febrile seizures. Incidence peaked at 16.7 months of age (median: 16.7 months, interquartile range: 12.5–24.0). The 5-year cumulative incidence of febrile seizures increased with decreasing birth weight (<1500 g; 5.42% (95% CI: 4.98–5.88% vs. 3,000–4,000 g; 3.53% (95% CI: 3.50–3.56%)) and with decreasing gestational age at birth (31–32 weeks; 5.90% (95% CI: 5.40–6.44%) vs. 39–40 weeks; 3.56% (95% CI: 3.53–3.60)). Lower gestational age at birth was associated with higher age at onset of a first febrile seizure; an association that essentially disappeared when correcting for age from conception. Conclusions: The risk of febrile seizures increased with decreasing birth weight and gestational age at birth. The association between low gestational age at birth and age at first febrile seizure suggests that onset of febrile seizures is associated with the stage of brain development.

AB - Objective: Febrile seizure is a common childhood disorder that affects 2–5% of all children, and is associated with later development of epilepsy and psychiatric disorders. This study determines how the incidence of febrile seizures correlates with birth characteristics, age, sex and brain development. Methods: This is a cohort study of all children born Denmark between 1977 and 2011 who were alive at 3 months of age (N = 2,103,232). The Danish National Patient Register was used to identify children with febrile seizures up to 5 years of age. Follow-up ended on 31 December 2016 when all cohort members had potentially reached 5 years of age. Results: In total, 75,593 (3.59%, 95% CI: 3.57–3.62%) were diagnosed with febrile seizures. Incidence peaked at 16.7 months of age (median: 16.7 months, interquartile range: 12.5–24.0). The 5-year cumulative incidence of febrile seizures increased with decreasing birth weight (<1500 g; 5.42% (95% CI: 4.98–5.88% vs. 3,000–4,000 g; 3.53% (95% CI: 3.50–3.56%)) and with decreasing gestational age at birth (31–32 weeks; 5.90% (95% CI: 5.40–6.44%) vs. 39–40 weeks; 3.56% (95% CI: 3.53–3.60)). Lower gestational age at birth was associated with higher age at onset of a first febrile seizure; an association that essentially disappeared when correcting for age from conception. Conclusions: The risk of febrile seizures increased with decreasing birth weight and gestational age at birth. The association between low gestational age at birth and age at first febrile seizure suggests that onset of febrile seizures is associated with the stage of brain development.

KW - birth weight

KW - brain development

KW - febrile seizures and epilepsy

KW - gestational age

UR - http://www.scopus.com/inward/record.url?scp=85103574099&partnerID=8YFLogxK

U2 - 10.1111/ane.13420

DO - 10.1111/ane.13420

M3 - Journal article

C2 - 33822360

AN - SCOPUS:85103574099

VL - 144

SP - 51

EP - 57

JO - Acta Neurologica Scandinavica

JF - Acta Neurologica Scandinavica

SN - 0001-6314

IS - 1

ER -