Institut for Biomedicin

Jacob Giehm Mikkelsen

Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA

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Strategies leading to the long-term suppression of inappropriate ocular angiogenesis are required to avoid the need for repetitive monthly injections for treatment of diseases of the eye, such as age-related macular degeneration (AMD). The present study aimed to develop a strategy for the sustained repression of vascular endothelial growth factor (VEGF), which is identified as the key player in exudative AMD.
OriginalsprogEngelsk
TidsskriftJournal of Gene Medicine (Online)
Vol/bind14
Nummer11
Sider (fra-til)632-41
Antal sider10
ISSN1099-498X
DOI
StatusUdgivet - 2012

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