Inger Mechlenburg

Efficacy of pre-operative progressive resistance training on post-operative outcomes in patients undergoing total knee arthroplasty

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OBJECTIVE: To investigate the efficacy of 4 weeks of pre-operative and 4-week post-operative progressive resistance training (PRT) compared to 4 weeks of post-operative PRT only on functional performance, muscle strength and patient-reported outcomes in patients undergoing total knee arthroplasty (TKA).

METHODS: In total 59 patients were randomized to 4 weeks of pre-operative PRT (intervention group) or to a group who "lived as usual" (control group). Both groups performed 4 weeks of PRT after TKA. At 6 and 1 weeks before TKA, and at 1, 6 and 12 weeks after TKA performance-based measures (30s chair stand test (30sCST), timed-up-and-go (TUG) and walking tests), knee extensor and flexor muscle strength (dynamometry), patient-reported functional performance, health-related quality of life, and pain scores were evaluated.

RESULTS: When comparing the changes from baseline to the primary test point 6 weeks after TKA, a significant group difference in favor of the intervention group was found for the 30sCST (2.5 rep. (0.9;4.1) vs. -1.1 rep. (-2.8;0.7), p<0.004), the TUG (-0.7 sec (-1.6;0.1) vs. 0.8 sec (-0.1;1.7), p=0.015), normalized knee extensor muscle strength (-0.2 Nm/kg (-0.3;-0.1) vs. -0.4 Nm/kg (-0.5;-0.3), p=0.002) and normalized knee flexor muscle strength (0.1 Nm/kg (0.0;0.2) vs. 0.0 Nm/kg (-0.1;0.1), p=0.016). No differences were found between groups on patient-reported outcomes.

CONCLUSION: Supervised pre-operative PRT is an efficacious and safe intervention for improving post-operative functional performance and muscle strength, but improvements in patient-reported outcomes were not detected. This article is protected by copyright. All rights reserved.

TidsskriftArthritis Care & Research
StatusUdgivet - 29 dec. 2015

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