Iben Blaabjerg Sundtoft

Cervical Collagen Concentration within Fifteen Months after Delivery

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  • Gynækologisk/Obstetrisk afd. Y- SKS
OBJECTIVE: Cervical collagen concentration decreases during pregnancy. The increased risk of preterm birth following a short interpregnancy interval may be explained by an incomplete remodeling of the cervix. The objective of this study was to describe the changes in cervical collagen concentration over 15 months following delivery.
METHODS: The collagen concentrations were determined in cervical biopsies obtained from 15 women at 3, 6, 9, 12, and 15 months after delivery.
RESULTS: The mean cervical collagen concentrations were 50, 59, 63, 65, and 65 % of dry weight (SD 4.2 – 6.5). This increase was statistically significant until month 9, but not between months 9 and 12.
CONCLUSIONS: Low collagen concentrations in the uterine cervix may contribute to the association between a short interpregnancy interval and preterm birth.
OriginalsprogEngelsk
TidsskriftAmerican Journal of Obstetrics and Gynecology
Vol/bind205
Nummer1
Sider (fra-til)59.e1-3
ISSN0002-9378
StatusUdgivet - jul. 2011
BegivenhedNordic Congress of Obstetrics and Gynecology, NFOG 2010 - Copenhagen, Danmark
Varighed: 15 jun. 201018 jun. 2010
Konferencens nummer: 37th

Konference

KonferenceNordic Congress of Obstetrics and Gynecology, NFOG 2010
Nummer37th
LandDanmark
ByCopenhagen
Periode15/06/201018/06/2010

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