Henrik Gammelager

Perioperative Doppler measurements of renal perfusion are associated with acute kidney injury in patients undergoing cardiac surgery

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Perioperative Doppler measurements of renal perfusion are associated with acute kidney injury in patients undergoing cardiac surgery. / Hermansen, Johan Lyngklip; Pettey, Gabriela; Sørensen, Heidi Tofte; Nel, Samantha; Tsabedze, Nqoba; Hørlyck, Arne; Chakane, Palesa Motshabi; Gammelager, Henrik; Juhl-Olsen, Peter.

I: Scientific Reports, Bind 11, Nr. 1, 19738, 12.2021.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

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Hermansen, Johan Lyngklip ; Pettey, Gabriela ; Sørensen, Heidi Tofte ; Nel, Samantha ; Tsabedze, Nqoba ; Hørlyck, Arne ; Chakane, Palesa Motshabi ; Gammelager, Henrik ; Juhl-Olsen, Peter. / Perioperative Doppler measurements of renal perfusion are associated with acute kidney injury in patients undergoing cardiac surgery. I: Scientific Reports. 2021 ; Bind 11, Nr. 1.

Bibtex

@article{032ce7d7dde448a0b7651ead64f45e91,
title = "Perioperative Doppler measurements of renal perfusion are associated with acute kidney injury in patients undergoing cardiac surgery",
abstract = "Acute kidney injury (AKI) is a frequent and severe complication in cardiac surgery. Normal renal function is dependent on adequate renal perfusion, which may be altered in the perioperative period. Renal perfusion can be assessed with Doppler measurement. We aimed to determine the association between Doppler measurements of renal perfusion and the development of AKI. This was a prospective, observational study of 100 patients with ≥ one risk factor for postoperative AKI undergoing open-heart surgery. Doppler ultrasound examinations were performed before surgery and on the first and fourth postoperative day. AKI was defined according to the KDIGO criteria and subdivided into mild (KDIGO stage 1) and severe AKI (KDIGO stage 2 + 3). Thirty-three patients developed AKI, 25 developed mild and eight developed severe AKI. Abnormal renal venous flow pattern on the first postoperative day was significantly associated with the development of severe AKI (OR 8.54 (95% CI 1.01; 72.2), P = 0.046), as were portal pulsatility fraction (OR 1.07 (95% CI 1.02; 1.13), P = 0.005). Point-of-care Doppler ultrasound measurements of renal perfusion are associated with the development of AKI after cardiac surgery. Renal and portal Doppler ultrasonography can be used to identify patients at high risk or very low risk of AKI after cardiac surgery.",
author = "Hermansen, {Johan Lyngklip} and Gabriela Pettey and S{\o}rensen, {Heidi Tofte} and Samantha Nel and Nqoba Tsabedze and Arne H{\o}rlyck and Chakane, {Palesa Motshabi} and Henrik Gammelager and Peter Juhl-Olsen",
note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",
year = "2021",
month = dec,
doi = "10.1038/s41598-021-99141-y",
language = "English",
volume = "11",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",
number = "1",

}

RIS

TY - JOUR

T1 - Perioperative Doppler measurements of renal perfusion are associated with acute kidney injury in patients undergoing cardiac surgery

AU - Hermansen, Johan Lyngklip

AU - Pettey, Gabriela

AU - Sørensen, Heidi Tofte

AU - Nel, Samantha

AU - Tsabedze, Nqoba

AU - Hørlyck, Arne

AU - Chakane, Palesa Motshabi

AU - Gammelager, Henrik

AU - Juhl-Olsen, Peter

N1 - Publisher Copyright: © 2021, The Author(s).

PY - 2021/12

Y1 - 2021/12

N2 - Acute kidney injury (AKI) is a frequent and severe complication in cardiac surgery. Normal renal function is dependent on adequate renal perfusion, which may be altered in the perioperative period. Renal perfusion can be assessed with Doppler measurement. We aimed to determine the association between Doppler measurements of renal perfusion and the development of AKI. This was a prospective, observational study of 100 patients with ≥ one risk factor for postoperative AKI undergoing open-heart surgery. Doppler ultrasound examinations were performed before surgery and on the first and fourth postoperative day. AKI was defined according to the KDIGO criteria and subdivided into mild (KDIGO stage 1) and severe AKI (KDIGO stage 2 + 3). Thirty-three patients developed AKI, 25 developed mild and eight developed severe AKI. Abnormal renal venous flow pattern on the first postoperative day was significantly associated with the development of severe AKI (OR 8.54 (95% CI 1.01; 72.2), P = 0.046), as were portal pulsatility fraction (OR 1.07 (95% CI 1.02; 1.13), P = 0.005). Point-of-care Doppler ultrasound measurements of renal perfusion are associated with the development of AKI after cardiac surgery. Renal and portal Doppler ultrasonography can be used to identify patients at high risk or very low risk of AKI after cardiac surgery.

AB - Acute kidney injury (AKI) is a frequent and severe complication in cardiac surgery. Normal renal function is dependent on adequate renal perfusion, which may be altered in the perioperative period. Renal perfusion can be assessed with Doppler measurement. We aimed to determine the association between Doppler measurements of renal perfusion and the development of AKI. This was a prospective, observational study of 100 patients with ≥ one risk factor for postoperative AKI undergoing open-heart surgery. Doppler ultrasound examinations were performed before surgery and on the first and fourth postoperative day. AKI was defined according to the KDIGO criteria and subdivided into mild (KDIGO stage 1) and severe AKI (KDIGO stage 2 + 3). Thirty-three patients developed AKI, 25 developed mild and eight developed severe AKI. Abnormal renal venous flow pattern on the first postoperative day was significantly associated with the development of severe AKI (OR 8.54 (95% CI 1.01; 72.2), P = 0.046), as were portal pulsatility fraction (OR 1.07 (95% CI 1.02; 1.13), P = 0.005). Point-of-care Doppler ultrasound measurements of renal perfusion are associated with the development of AKI after cardiac surgery. Renal and portal Doppler ultrasonography can be used to identify patients at high risk or very low risk of AKI after cardiac surgery.

U2 - 10.1038/s41598-021-99141-y

DO - 10.1038/s41598-021-99141-y

M3 - Journal article

C2 - 34611205

VL - 11

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

IS - 1

M1 - 19738

ER -