Hanne Primdahl

Oncocytic carcinoma of the salivary glands: A Danish national study

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

DOI

  • Marie Westergaard-Nielsen, Department of ORL - Head and Neck Surgery, Odense University Hospital, Denmark. Electronic address: marie.westergaard-nielsen@rsyd.dk.
  • ,
  • Christian Godballe, Department of ORL - Head and Neck Surgery; Department of Oncology, Odense University Hospital, Odense, Denmark.
  • ,
  • Lisbeth Juhler Andersen, Department of Oncology, Aalborg University Hospital, Aalborg, Denmark.
  • ,
  • Hanne Primdahl
  • Claus A Kristensen, Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
  • ,
  • Elo Andersen, Department of Oncology, Herlev Hospital, Denmark.
  • ,
  • Kristine Bjørndal, Department of ORL - Head and Neck Surgery; Department of Oncology, Odense University Hospital, Odense, Denmark.
OBJECTIVES:
To present a Danish national series of oncocytic carcinoma (OC) patients, including data on treatment, recurrence and survival.
METHODS:
From the national Danish database of salivary gland carcinomas, all patients diagnosed with OC from 1990 to 2005 were identified and data concerning demographics, tumor site, clinical stage and treatment profiles were extracted. A follow-up was carried out.
RESULTS:
Of the 15 cases of salivary gland OC, eight were female. The incidence was 0.02/100.000 inhabitants per year in Denmark, 13 patients presented with OC in the parotid gland and two patients with OC in the submandibular gland. Eight patients had nodal involvement at the time of diagnosis. None of the patients had distant metastases at the time of diagnosis. All patients were treated with primary surgery and seven patients received adjuvant radiotherapy. Half of the patients had recurrence. Six patients were alive at 5 years follow up and one patient was alive without recurrence at 10 years follow up.
CONCLUSIONS:
This study is the first to report a national incidence of oncocytic carcinoma in the salivary glands. The results confirm oncocytic carcinoma to be a salivary gland carcinoma with a poor prognosis. All patients experiencing recurrence died of the disease. Treatment must be aggressive. National registries are necessary to achieve further knowledge for future treatment recommendations.
OriginalsprogEngelsk
TidsskriftAuris Nasus Larynx
Vol/bind45
Nummer4
Sider (fra-til)825-830
Antal sider6
ISSN0385-8146
DOI
StatusUdgivet - 2018

Se relationer på Aarhus Universitet Citationsformater

ID: 119187080