Hamidreza Ardalani


Hamidreza Ardalani


I received my M.Sc. in chemistry of medicinal plants at IAU, Iran, where I studied the effects of plant’s hormones on biochemical responses. Meantime, I was involved in the researches about the clinical efficacy of plant’s secondary metabolites (PSMs) on hyperlipidemia, hypertension and diabetes. As a research assistant at University of Copenhagen, I conducted a study on metabolite profiling of endophytic fungi to discover antidiabetic and antibiotic compounds and validated a high-resolution method to find the antibacterial bioactive compounds from complex crude extracts. Currently, I am working on my Ph.D. at Aarhus University, studying the uptake and metabolization of phytochemicals and pesticides in honey bees. I endeavor to clarify some agro-chemical inquiries using a combination of state-of-the-art techniques such as chromatography, mass spectrometry, RT-qPCR and metabolomics.


Ph.D. project: Uptake and metabolisation of phytochemicals and pesticides in honey bees

Aims: Honey bees are ideal pollinators and subject to numerous stresses such as reduced flower diversity, new parasites, and chronical exposure to agrochemicals. In this project, I attempt to investigate the effects of PSMs on the detoxification system of honey bees and the sacbrood virus (SBV) level when the bees are co-exposed to selected pesticides. The combination of analytical techniques (LC-Qtrap-MS/MS, GC-TOF-MS, UPLC-Orbitrap-MS/MS, NMR), biological approaches (RT-qPCR), and state-of-the-art metabolomics will provide a comprehensive approach in addressing agro-ecological questions. Investigating how PSMs can up-regulate bees' systems to detoxify xenobiotics and identification of the enzymes involved in this process can elucidate how bees face the toxicity of chemicals in an agricultural setting.




Natural products chemistry

Chemical ecology


ID: 118840795