Birgitte Vrou Offersen

Professor, Klinisk professor

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Birgitte Vrou Offersen

Klinisk professor

  • Institut for Klinisk Medicin - Eksperimentel Klinisk Onkologi
Postaddresse:
Palle Juul-Jensens Boulevard 35
8200
Aarhus N
Danmark

E-mail: bvo@oncology.au.dk

Fødselsår

1968

Uddannelser

2007Speciallæge, Afdelingen for Experimental Klinisk Onkologi, Aarhus Universitetshospital, Danmark
2002Ph.d., hvor ?
1995Cand. Med., hvor ?
1987Mat.-Fys. Student, hvorfra ?

Akademiske grader

2002Ph.d., Methodological and prognostic evaluation of immunohistochemical assessment of angiogenesis in human carcinomas.
1995Diplomeksamen, Udvikling af metode til vurdering af angiogenese i humane tumorer.

Forskningsområder

Clinical radiation oncology and breast cancer

Nuværende ansættelse

2011-Klinisk lektor, Aarhus Universitet, Danmark

Tidligere ansættelser

2009Overlæge, Onkologisk afdeling, Århus Sygehus, Danmark
2007-2009Afdelingslæge, Onkologisk afdeling, Århus Sygehus, Danmark
20071. Reservelæge, Onkologisk afdeling, Århus Sygehus, Danmark
2006-20071. Reservelæge, Onkologisk afdeling, Ålborg Sygehus, Danmark
2004-2006Kursusreservelæge, Onkologisk afdeling, Århus Sygehus, Danmark
2002-2003Introduktionsstilling, Onkologisk afdeling, Århus Sygehus, Danmark
2003-2004Intern Medicin, Randers Centralsygehus, Danmark
1997-2002Ph.d.-studerende, Afdeling for Eksperimentel Klinisk Onkologi, Århus Sygehus, Danmark
1996-1997Turnus, Almen praksis, Kolding
1995-1996Turnus, Medicinsk og Ortopædkirurgiske afdelinger, Kolding Sygehus, Danmark

Publikationer og præsentationer

Publikationer: ?, Peer-reviewed artikler: ?, Bogkapitler: ?, H-index: ?, Citations: ?, Patenter: ?, Præsentationer ved videnskabelige møder (oral): ?

Udvalgs- og bestyrelsesposter

Chair on ESTRO workshop for target delineation in adjuvant breast radiotherapy (2012-)
Consultant, Department of Oncology, Aarhus University Hospital, Denmark (2010-)
Board member of Danish Breast Cancer Cooperative Group (DBCG) (2009-)
Secretary of committee for radiotherapy

Dansk Selskab for Klinisk Onkologi DSKO
European Society for Therapeutic Radiology and Oncology ESTRO
DBCG Radioterapi Udvalg
Danish Center for Interventional Research in Radiation oncology (CIRRO)
Flims Alumni Club

Medlem af DBCG's Bestyrelse (2009-)
Sekretær i DBCG's Radioterapi Udvalg (2008-)
Sekretær i FYO's bestyrelse (2006-2008).

Organisering af kliniske forsøg

Hovedinvestigator på DBCG HYPO og DBCG PBI (2009)
Hovedinvestigator på DBCG SIB, er nu i planlægningsfasen (start 2014)
Er Co.-investigator på ALLTO-protokollen (adjuverende trastuzumab/Lapatinib)

Vejledning

Vejleder for e Ph.d.-studerende, som undersøger værdien af bestråling af de parasternale lymfeknuder ved lymfeknudepositiv brystkræft


Bedømmelser

x

Priser og udmærkelser

I forbindelse med DBCG protokoller, ansøgt og fået penge til deltidsfrikøb fra klinikken fra Kræftens Bekæmpelse (2010)
Legat fra Breast Friends
Agnes Niebuhr Anderssons Mindefond (2009)

Større forskningsbevillinger

x

Ekstern bedømmer for fonde

x

Organisering af møder

x

Involvering i videnskabelige tidsskrifter

Radiotherapy and Oncology
British Journal of Cancer
Acta Oncologica
Lung Cancer

Medlemsskaber


x

Publikationer

Lymphatic Function in the Arms of Breast Cancer Patients-A Prospective Cohort Study

Alstrup, M., Johannessen, A. L., Mohanakumar, S., Offersen, B. V. & Hjortdal, V. E., aug. 2021, I: Plastic and Reconstructive Surgery - Global Open. 9, 8, s. e3779

Superficial margins in skin sparing and nipple sparing mastectomies for DCIS: A margin of potential concern

Tramm, T., Christiansen, P., Offersen, B. V., Madsen, K. B., Poortmans, P. & Kaidar-Person, O., aug. 2021, I: Radiotherapy and Oncology. 161, s. 177-182 6 s.

The Financial Impact on Reimbursement of Moderately Hypofractionated Postoperative Radiation Therapy for Breast Cancer: An International Consortium Report

Marta, G. N., Ramiah, D., Kaidar-Person, O., Kirby, A., Coles, C., Jagsi, R., Hijal, T., Sancho, G., Zissiadis, Y., Pignol, J. P., Ho, A. Y., Cheng, S. H. C., Offersen, B. V., Meattini, I. & Poortmans, P., maj 2021, I: Clinical Oncology. 33, 5, s. 322-330 9 s.

Risk of coronary artery disease after adjuvant radiotherapy in 29,662 early breast cancer patients: A population-based Danish Breast Cancer Group study

Milo, M. L. H., Thorsen, L. B. J., Paaske Johnsen, S., Nielsen, K. M., Brink Valentin, J., Alsner, J. & Offersen, B. V., apr. 2021, I: Radiotherapy & Oncology. 157, s. 106-113 8 s.

Selection criteria for early breast cancer patients in the DBCG proton trial – The randomised phase III trial strategy

Stick, L. B., Lorenzen, E. L., Yates, E. S., Anandadas, C., Andersen, K., Aristei, C., Byrne, O., Hol, S., Jensen, I., Kirby, A. M., Kirova, Y. M., Marrazzo, L., Matías-Pérez, A., Nielsen, M. M. B., Nissen, H. D., Oliveros, S., Verhoeven, K., Vikström, J. & Offersen, B. V., mar. 2021, I: Clinical and Translational Radiation Oncology. 27, s. 126-131 6 s.

Patient-reported outcomes in postmenopausal breast cancer survivors–comparisons with normative data

Nielsen, A. W. M., Kristensen, M. H., Offersen, B. V., Alsner, J., Zachariae, R. & Nielsen, H. M., jan. 2021, I: Acta Oncologica. 60, 1, s. 78-86 9 s.

Postmastectomy Radiation Therapy Planning After Immediate Implant-based Reconstruction Using the European Society for Radiotherapy and Oncology-Advisory Committee in Radiation Oncology Practice Consensus Guidelines for Target Volume Delineation

Kaidar-Person, O., Nissen, H. D., Yates, E. S., Andersen, K., Boersma, L. J., Boye, K., Canter, R., Costa, E., Daniel, S., Hol, S., Jensen, I., Lorenzen, E. L., Mjaaland, I., Nielsen, M. E. K., Poortmans, P., Vikström, J., Webb, J. & Offersen, B. V., jan. 2021, I: Clinical Oncology. 33, 1, s. 20-29 10 s.

Radiation oncology in the new virtual and digital era

Aznar, M. C., Bacchus, C., Coppes, R. P., Deutsch, E., Georg, D., Haustermans, K., Hoskin, P., Krause, M., Lartigau, E. F., Löck, S., Offersen, B., Overgaard, J., Thwaites, D. I., van der Kogel, A. J., van der Heide, U. A., Valentini, V. & Baumann, M., jan. 2021, I: Radiotherapy and Oncology. 154, s. A1-A4

5th ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 5)

Cardoso, F., Paluch-Shimon, S., Senkus, E., Curigliano, G., Aapro, M. S., André, F., Barrios, C. H., Bergh, J., Bhattacharyya, G. S., Biganzoli, L., Boyle, F., Cardoso, M. J., Carey, L. A., Cortés, J., El Saghir, N. S., Elzayat, M., Eniu, A., Fallowfield, L., Francis, P. A., Gelmon, K., Gligorov, J., Haidinger, R., Harbeck, N., Hu, X., Kaufman, B., Kaur, R., Kiely, B. E., Kim, S. B., Lin, N. U., Mertz, S. A., Neciosup, S., Offersen, B. V., Ohno, S., Pagani, O., Prat, A., Penault-Llorca, F., Rugo, H. S., Sledge, G. W., Thomssen, C., Vorobiof, D. A., Wiseman, T., Xu, B., Norton, L., Costa, A. & Winer, E. P., dec. 2020, I: Annals of Oncology. 31, 12, s. 1623-1649 27 s.

Analysis of cardiac substructure dose in a large, multi-centre danish breast cancer cohort (the DBCG HYPO trial): Trends and predictive modelling

Finnegan, R., Lorenzen, E. L., Dowling, J., Jensen, I., Berg, M., Thomsen, M. S., Delaney, G. P., Koh, E. S., Thwaites, D., Brink, C., Offersen, B. V. & Holloway, L., dec. 2020, I: Radiotherapy and Oncology. 153, s. 130-138 9 s.

Rates of re-excision and conversion to mastectomy after breast-conserving surgery with or without oncoplastic surgery: a nationwide population-based study

Heeg, E., Jensen, M. B., Holmich, L. R., Bodilsen, A., Tollenaar, R. A. E. M., Laenkholm, A. V., Offersen, B. V., Ejlertsen, B., Mureau, M. A. M. & Christiansen, P. M., dec. 2020, I: British Journal of Surgery. 107, 13, s. 1762-1772 11 s.

Fully automated detection of heart irradiation in cine MV images acquired during breast cancer radiotherapy

Poulsen, P. R., Thomsen, M. S., Hansen, R., Worm, E., Spejlborg, H. & Offersen, B., nov. 2020, I: Radiotherapy & Oncology. 152, s. 189-195 7 s.

Hypofractionated Versus Standard Fractionated Radiotherapy in Patients With Early Breast Cancer or Ductal Carcinoma In Situ in a Randomized Phase III Trial: The DBCG HYPO Trial

Offersen, B. V., Alsner, J., Nielsen, H. M., Jakobsen, E. H., Nielsen, M. H., Krause, M., Stenbygaard, L., Mjaaland, I., Schreiber, A., Kasti, U. M., Overgaard, J. & Danish Breast Cancer Group Radiation Therapy Committee, nov. 2020, I: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 38, 31, s. 3615-3625 11 s.

Patterns in detection of recurrence among patients treated for breast cancer

Saltbaek, L., Horsboel, T. A., Offersen, B. V., Andersson, M., Friberg, A. S., Skriver, S. K., Bidstrup, P. E., Overgaard, J., Johansen, C. & Dalton, S. O., nov. 2020, I: Breast Cancer Research and Treatment. 184, 2, s. 365-373 9 s.

Delineation of whole heart and substructures in thoracic radiation therapy: National guidelines and contouring atlas by the Danish Multidisciplinary Cancer Groups

Milo, M. L. H., Offersen, B. V., Bechmann, T., Diederichsen, A. C. P., Hansen, C. R., Holtved, E., Josipovic, M., Lörincz, T., Maraldo, M. V., Nielsen, M. H., Nordsmark, M., Nyström, P. W., Pøhl, M., Rose, H. K., Schytte, T., Yates, E. S. & Lorenzen, E. L., sep. 2020, I: Radiotherapy and Oncology. 150, s. 121-127 7 s.

A validated algorithm for register-based identification of patients with recurrence of breast cancer—Based on Danish Breast Cancer Group (DBCG) data

Aagaard Rasmussen, L., Jensen, H., Flytkjær Virgilsen, L., Jellesmark Thorsen, L. B., Vrou Offersen, B. & Vedsted, P., 1 apr. 2019, I: Cancer epidemiology. 59, s. 129-134 6 s.

Adjuvant radiotherapy does not affect hemostasis

Begtrup, K. M., Hojbjerg, J. A., Offersen, B. V. & Hvas, A-M., mar. 2019, I: Platelets. 30, 3, s. 387-395 9 s.

ESTRO consensus guideline for target volume delineation in the setting of postmastectomy radiation therapy after implant-based immediate reconstruction for early stage breast cancer

Kaidar-Person, O., Vrou Offersen, B., Hol, S., Arenas, M., Aristei, C., Bourgier, C., Joao Cardoso, M., Chua, B., Coles, C. E., Engberg Damsgaard, T., Gabrys, D., Jagsi, R., Jimenez, R., Kirby, A. M., Kirkove, C., Kirova, Y., Kouloulias, V., Marinko, T., Meattini, I., Mjaaland, I., Nader Marta, G., Witt Nystrom, P., Senkus, E., Skyttä, T., Tvedskov, T. F., Verhoeven, K. & Poortmans, P., 2019, I: Radiotherapy and Oncology. 137, s. 159-166 8 s.

4th ESO-ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 4)†

Cardoso, F., Senkus, E., Costa, A., Papadopoulos, E., Aapro, M., André, F., Harbeck, N., Aguilar Lopez, B., Barrios, C. H., Bergh, J., Biganzoli, L., Boers-Doets, C. B., Cardoso, M. J., Carey, L. A., Cortés, J., Curigliano, G., Diéras, V., El Saghir, N. S., Eniu, A., Fallowfield, L., Francis, P. A., Gelmon, K., Johnston, S. R. D., Kaufman, B., Koppikar, S., Krop, I. E., Mayer, M., Nakigudde, G., Offersen, B. V., Ohno, S., Pagani, O., Paluch-Shimon, S., Penault-Llorca, F., Prat, A., Rugo, H. S., Sledge, G. W., Spence, D., Thomssen, C., Vorobiof, D. A., Xu, B., Norton, L. & Winer, E. P., 1 aug. 2018, I: Annals of Oncology. 29, 8, s. 1634-1657 24 s.

The Assisi Think Tank Meeting and Survey of post MAstectomy Radiation Therapy after breast reconstruction: The ATTM-SMART report

Aristei, C., Kaidar-Person, O., Tagliaferri, L., Arenas, M., Coles, C. E., Offersen, B. V., Frezza, G., Leonardi, M. C., Valentini, V., Bourgier, C. & Poortmans, P. M. P., apr. 2018, I: European Journal of Surgical Oncology. 44, 4, s. 436-443 8 s.

Is DBCG abreast of new developments?

Offersen, B. V., Ejlertsen, B., Balslev, E., Flyger, H., Gerdes, A-M., Hansen, M. K., Hølmich, L. R., Jensen, M-B., Kristensen, B., Laenkholm, A-V., Mouridsen, H. T., Nielsen, M. H., Overgaard, J., Tuxen, M., Vejborg, I. & Christiansen, P., 18 jan. 2018, I: Acta Oncologica. 57, 1, s. 1-2 2 s.

Breast conserving surgery versus mastectomy: overall and relative survival-a population based study by the Danish Breast Cancer Cooperative Group (DBCG)

Christiansen, P., Carstensen, S. L., Ejlertsen, B., Kroman, N., Offersen, B., Bodilsen, A. & Jensen, M-B., jan. 2018, I: Acta Oncologica. 57, 1, s. 19-25 7 s.

DBCG hypo trial validation of radiotherapy parameters from a national data bank versus manual reporting

Brink, C., Lorenzen, E. L., Krogh, S. L., Westberg, J., Berg, M., Jensen, I., Thomsen, M. S., Yates, E. S. & Offersen, B. V., jan. 2018, I: Acta Oncologica. 57, 1, s. 107-112 6 s.

Forty years of landmark trials undertaken by the Danish Breast Cancer Cooperative Group (DBCG) nationwide or in international collaboration

Ejlertsen, B., Offersen, B. V., Overgaard, J., Christiansen, P., Jensen, M-B., Kroman, N., Knoop, A. S. & Mouridsen, H., jan. 2018, I: Acta Oncologica. 57, 1, s. 3-12 10 s.

The clinical database and implementation of treatment guidelines by the Danish Breast Cancer Cooperative Group in 2007-2016

Jensen, M-B., Laenkholm, A-V., Offersen, B. V., Christiansen, P., Kroman, N., Mouridsen, H. T. & Ejlertsen, B., jan. 2018, I: Acta Oncologica. 57, 1, s. 13-18 6 s.

The potential benefits from respiratory gating for breast cancer patients regarding target coverage and dose to organs at risk when applying strict dose limits to the heart: results from the DBCG HYPO trial

Berg, M., Lorenzen, E. L., Jensen, I., Thomsen, M. S., Lutz, C. M., Refsgaard, L., Nissen, H. D. & Offersen, B. V., jan. 2018, I: Acta Oncologica. 57, 1, s. 113-119 7 s.

Pectus excavatum and adjuvant radiotherapy for early stage breast cancer: balancing dose to target versus heart

Milo, M. L. H., Spejlborg, H., Thorsen, L. B. J. & Offersen, B. V., nov. 2017, I: Acta Oncologica. 56, 11, s. 1653-1656 4 s.

Loco-regional morbidity after breast conservation and axillary lymph node dissection for early breast cancer with or without regional nodes radiotherapy, perspectives in modern breast cancer treatment: the Skagen Trial 1 is active

Nielsen, H. M., Friis, R. B., Linnet, S. & Offersen, B. V., maj 2017, I: Acta Oncologica. 56, 5, s. 713-718 6 s.

Quality assessment of delineation and dose planning of early breast cancer patients included in the randomized Skagen Trial 1

Francolini, G., Thomsen, M. S., Yates, E. S., Kirkove, C., Jensen, I., Blix, E. S., Kamby, C., Nielsen, M. H., Krause, M., Berg, M., Mjaaland, I., Schreiber, A., Kasti, U-M., Boye, K. & Offersen, B. V., maj 2017, I: Radiotherapy & Oncology. 123, 2, s. 282-287 6 s.

Dosimetric assessment of an Atlas based automated segmentation for loco-regional radiation therapy of early breast cancer in the Skagen Trial 1: A multi-institutional study

Ibrahim, A. R. M. E., Francolini, G., Thomsen, M. S., Yates, E. S., Nyeng, T. B., Kirkove, C., Kamby, C., Blix, E. S., Nielsen, M. H., Taheri-Kadkhoda, Z., Berg, M. & Offersen, B. V., 2017, I: Clinical and Translational Radiation Oncology. 2, s. 36-40 5 s.

Loco-regional morbidity after breast conservation and axillary lymph node dissection for early breast cancer with or without regional nodes radiotherapy, perspectives in modern breast cancer treatment: the Skagen Trial 1 is active

Nielsen, H. M., Friis, R. B., Linnet, S. & Offersen, B. V., 2017, I: Acta Oncologica. Supplement. 56, 5, s. 713-718 6 s.

Internal and external validation of an ESTRO delineation guideline - dependent automated segmentation tool for loco-regional radiation therapy of early breast cancer

Ibrahim, A. R. M. E., Yates, E. S., Nyeng, T. B., Thomsen, M. S., Nielsen, H. M., Poortmans, P., Kirkove, C., Krause, M., Kamby, C., Mjaaland, I., Blix, E. S., Jensen, I., Berg, M., Lorenzen, E. L., Taheri-Kadkhoda, Z. & Offersen, B. V., dec. 2016, I: Radiotherapy & Oncology. 121, 3, s. 424-430 7 s.

Radiation-induced morbidity evaluated by high-frequency ultrasound

Schack, L. M. H., Alsner, J., Overgaard, J., Andreassen, C. N. & Offersen, B. V., dec. 2016, I: Acta Oncologica. 55, 12, s. 1498-1500 3 s.

The 2016 Assisi Think Tank Meeting on breast cancer: white paper

Aristei, C., Kaidar-Person, O., Arenas, M., Coles, C., Offersen, B. V., Bourgier, C., Frezza, G., Leonardi, M. C., Valentini, V. & Poortmans, P. M. P., nov. 2016, I: Breast Cancer Research and Treatment. 160, 2, s. 211-221 11 s.

Cardiovascular complications following thoracic radiotherapy in patients with cancer

Nielsen, K. M., Borchsenius, J. I. H., Offersen, B. V., Langer, S. W., Nielsen, H. M., Rasmussen, V. G. & Hansen, P. R., 26 sep. 2016, I: Ugeskrift for Laeger. 178, 39

Pattern of relapse after breast conserving therapy, a study of 1519 early breast cancer patients treated in the Central Region of Denmark 2000-2009

Bodilsen, A., Offersen, B. V., Christiansen, P. & Overgaard, J., 6 maj 2016, I: Acta Oncologica. s. 1-6 6 s.

Importance of margin width in breast-conserving treatment of early breast cancer

Bodilsen, A., Bjerre, K., Offersen, B. V., Vahl, P., Amby, N., Dixon, J. M., Ejlertsen, B., Overgaard, J. & Christiansen, P., maj 2016, I: Journal of Surgical Oncology. 113, 6, s. 609-15 7 s.

DBCG-IMN: A Population-Based Cohort Study on the Effect of Internal Mammary Node Irradiation in Early Node-Positive Breast Cancer

Thorsen, L. B. J., Offersen, B. V., Danø, H., Berg, M., Jensen, I., Pedersen, A. N., Zimmermann, S. J., Brodersen, H-J., Overgaard, M. & Overgaard, J., 1 feb. 2016, I: Journal of Clinical Oncology. 34, 4, s. 314-20 7 s.

ESTRO consensus guideline on target volume delineation for elective radiation therapy of early stage breast cancer, version 1.1

Offersen, B. V., Boersma, L. J., Kirkove, C., Hol, S., Aznar, M. C., Sola, A. B., Kirova, Y. M., Pignol, J-P., Remouchamps, V., Verhoeven, K., Weltens, C., Arenas, M., Gabrys, D., Kopek, N., Krause, M., Lundstedt, D., Marinko, T., Montero, A., Yarnold, J. & Poortmans, P., jan. 2016, I: Radiotherapy & Oncology. 118, 1, s. 205-8 4 s.

Setup error and motion during deep inspiration breath-hold breast radiotherapy measured with continuous portal imaging

Lutz, C. M., Poulsen, P. R., Fledelius, W., Offersen, B. V. & Thomsen, M. S., 2016, I: Acta Oncologica. 55, 2, s. 193-200 8 s.

Guidelines for time-to-event end point definitions in breast cancer trials: results of the DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer trials)

Gourgou-Bourgade, S., Cameron, D., Poortmans, P., Asselain, B., Azria, D., Cardoso, F., A'Hern, R., Bliss, J., Bogaerts, J., Bonnefoi, H., Brain, E., Cardoso, M. J., Chibaudel, B., Coleman, R., Cufer, T., Dal Lago, L., Dalenc, F., De Azambuja, E., Debled, M., Delaloge, S., Filleron, T., Gligorov, J., Gutowski, M., Jacot, W., Kirkove, C., MacGrogan, G., Michiels, S., Negreiros, I., Offersen, B. V., Penault Llorca, F., Pruneri, G., Roche, H., Russell, N. S., Schmitt, F., Servent, V., Thürlimann, B., Untch, M., van der Hage, J. A., van Tienhoven, G., Wildiers, H., Yarnold, J., Bonnetain, F., Mathoulin-Pélissier, S., Bellera, C. & Dabakuyo-Yonli, T. S., dec. 2015, I: Annals of Oncology. 26, 12, s. 2505-6 2 s.

The Influence of Repeat Surgery and Residual Disease on Recurrence After Breast-Conserving Surgery: A Danish Breast Cancer Cooperative Group Study

Bodilsen, A., Bjerre, K., Offersen, B. V., Vahl, P., Ejlertsen, B., Overgaard, J. & Christiansen, P., 16 jul. 2015, I: Annals of Surgical Oncology.

Regional radiotherapy in high-risk breast cancer: is the issue solved?

Krause, M., Petersen, C., Offersen, B. V. & Baumann, M., jul. 2015, I: British Journal of Radiology. 88, 1051, 20150071.

ESTRO consensus guideline on target volume delineation for elective radiation therapy of early stage breast cancer

Offersen, B. V., Boersma, L. J., Kirkove, C., Hol, S., Aznar, M. C., Biete Sola, A., Kirova, Y. M., Pignol, J-P., Remouchamps, V., Verhoeven, K., Weltens, C., Arenas, M., Gabrys, D., Kopek, N., Krause, M., Lundstedt, D., Marinko, T., Montero, A., Yarnold, J. & Poortmans, P., jan. 2015, I: Radiotherapy & Oncology. 114, 1, s. 3-10 8 s.

Regional recurrence after adjuvant breast cancer radiotherapy is not due to insufficient target coverage

Nielsen, H. M. & Offersen, B. V., jan. 2015, I: Radiotherapy & Oncology. 114, 1, s. 1-2 2 s.

CT-planned internal mammary node radiotherapy in the DBCG-IMN study: benefit versus potentially harmful effects

Thorsen, L. B. J., Thomsen, M. S., Berg, M., Jensen, I., Josipovic, M., Overgaard, M., Overgaard, J., Skogholt, P., Offersen, B. V. & Danish Breast Cancer Cooperative Group Radiotherapy Committee, aug. 2014, I: Acta Oncologica. 53, 8, s. 1027-34 8 s.

Is current evidence about intraoperative partial breast irradiation sufficient for broad implementation in clinical practice?

Kaidar-Person, O., Yarnold, J., Offersen, B. V. & Poortmans, P., jul. 2014, I: European Journal of Surgical Oncology. 40, 7, s. 791-3 3 s.

Inter-observer variation in delineation of the heart and left anterior descending coronary artery in radiotherapy for breast cancer: a multi-centre study from Denmark and the UK

Lorenzen, E. L., Taylor, C. W., Maraldo, M., Nielsen, M. H., Offersen, B. V., Andersen, M. R., O'Dwyer, D., Larsen, L., Duxbury, S., Jhitta, B., Darby, S. C., Ewertz, M. & Brink, C., aug. 2013, I: Radiotherapy & Oncology. 108, 2, s. 254-8 5 s.

Is regional nodes radiotherapy an alternative to surgery?

Offersen, B. V., Nielsen, H. M., Overgaard, M. & Overgaard, J., aug. 2013, I: Breast. 22, Suppl. 2, s. S118-S128 11 s.

Legal termination of a pregnancy resulting from transplanted cryopreserved ovarian tissue due to cancer recurrence

Ernst, EH., Offersen, B. V., Andersen, C. Y. & Ernst, E., jul. 2013, I: Journal of Assisted Reproduction and Genetics. 30, 7, s. 975-8 4 s.

Delineation of target volumes and organs at risk in adjuvant radiotherapy of early breast cancer: national guidelines and contouring atlas by the Danish Breast Cancer Cooperative Group

Nielsen, M. H., Berg, M., Pedersen, A. N., Andersen, K., Glavicic, V., Jakobsen, E. H., Jensen, I., Josipovic, M., Lorenzen, E. L., Nielsen, H. M., Stenbygaard, L., Thomsen, M. S., Vallentin, S., Zimmermann, S., Offersen, B. V. & Danish Breast Cancer Cooperative Group Radiotherapy Committee, maj 2013, I: Acta Oncologica. 52, 4, s. 703-10 8 s.

Quality assurance of conventional non-CT-based internal mammary lymph node irradiation in a prospective Danish Breast Cancer Cooperative Group trial: The DBCG-IMN study

Thorsen, L. B. J., Thomsen, M. S., Overgaard, M., Overgaard, J. & Offersen, B. V., 2013, I: Acta Oncologica. 52, 7, s. 1526-34 9 s.

Mortality rates among early-stage hormone receptor-positive breast cancer patients: a population-based cohort study in Denmark

Christiansen, P., Bjerre, K., Ejlertsen, B. L., Jensen, M-B., Rasmussen, B. B., Lænkholm, A-V., Kroman, N. T., Ewertz, M., Offersen, B. V., Toftdahl, D. B., Møller, S., Mouridsen, H. T. & Danish Breast Cancer Cooperative Group, 2011, I: National Cancer Institute. Journal (Print). 103, 18, s. 1363-72 10 s.

Radiation-induced heart morbidity after adjuvant radiotherapy of early breast cancer - Is it still an issue?

Offersen, B., Højris, I. & Overgaard, M., 2011, I: Radiotherapy & Oncology. 100, 2, s. 157-9 3 s.

Should Postmastectomy Radiotherapy to the Chest Wall and Regional Lymph Nodes Be Standard for Patients with 1-3 Positive Lymph Nodes?

Offersen, B. V., Brodersen, H-J., Nielsen, M. M., Overgaard, J. & Overgaard, M., 2011, I: Breast Care. 6, 5, s. 347-351 5 s.

Should postmastectomy radiotherapy to the chest wall and regional lymph nodes be standard for patients with 1–3 positive lymph nodes?

Offersen, B. V., Brodersen, H-J., Nielsen, M. M., Overgaard, J., Overgaard, M. & DBCG Radiotherapy Committee, 2011, I: Breast Care. 6, 5, s. 347-351 4 s.

Matrix metalloproteinase-9 measured in urine from bladder cancer patients is an independent prognostic marker of poor survival

Offersen, B. V., Knap, M. M., Horsman, M. R., Verheijen, J., Hanemaaijer, R. & Overgaard, J., 1 nov. 2010, I: Acta Oncologica. 49, 8, s. 1283-7 5 s.

Accelerated partial breast irradiation as part of breast conserving therapy of early breast carcinoma: A systematic review

Offersen, B. V., Overgaard, M., Kroman, N. & Overgaard, J., jan. 2009, I: Radiotherapy & Oncology. 90, 1, s. 1-13 13 s.

A comparison among HER2, TP53, PAI-1, angiogenesis, and proliferation activity as prognostic variables in tumours from 408 patients diagnosed with early breast cancer

Offersen, B. V., Alsner, J., Ege Olsen, K., Riisbro, R., Brünner, N., Sørensen, F. B., Sørensen, B. S., Schlemmer, B. O. & Overgaard, J., 2008, I: Acta Oncologica. 47, 4, s. 618-32 15 s.

A comparison between p53 accumulation determined by immunohistochemistry and TP53 mutations as prognostic variables in tumours from breast cancer patients

Alsner, J., Jensen, V., Kyndi, M., Offersen, B. V., Vu, P., Børresen-Dale, A-L. & Overgaard, J., 2008, I: Acta Oncologica. 47, 4, s. 600-7 8 s.

Urokinase plasminogen activator and plasminogen activator inhibitor type-1 in nonsmall-cell lung cancer: relation to prognosis and angiogenesis

Offersen, B. V., Pfeiffer, P., Andreasen, P. & Overgaard, J., jan. 2007, I: Lung Cancer. 56, 1, s. 43-50 8 s.

Lack of association between level of Plasminogen Activator Inhibitor-1 and estimates of tumor angiogenesis in early breast cancer

Danish Breast Cancer Cooperative Group (DBCG) Tumor Biology Committee, 2007, I: Acta Oncologica. 46, 6, s. 782-91 9 s.

Urokinase plasminogen activator and plasminogen activator inhibitor type-1 in non-small cell lung cancer: Relation to prognosis and angiogenesis.

Offersen, B. V., Pfeiffer, P., Andreasen, P. & Overgaard, J., 2007, I: Lung Cancer.

The prognostic relevance of estimates of proliferative activity in early breast cancer

Offersen, B. V., Sørensen, F. B., Knoop, A. & Overgaard, J., dec. 2003, I: Histopathology. 43, 6, s. 573-582 10 s.

The myofibroblast is the predominant plasminogen activator inhibitor-1-expressing cell type in human breast carcinomas

Offersen, B. V., Nielsen, B. S., Høyer-Hansen, G., Rank, F., Hamilton-Dutoit, S., Overgaard, J. & Andreasen, P. A., nov. 2003, I: American Journal of Pathology. 163, 5, s. 1887-1899 13 s.

Vitronectin in human breast carcinomas

Aaboe, M., Offersen, B. V., Christensen, A. & Andreasen, P., 20 maj 2003, I: B B A - Molecular Basis of Disease. 1638, 1, s. 72-82 11 s.

Quantification of angiogenesis as a prognostic marker in human carcinomas: acritical evaluation of histopathological methods for estimation of vascular density

Offersen, B. V., Borre, M. & Overgaard, J., maj 2003, I: European Journal of Cancer. 39, 7, s. 881-890 10 s.

Intense inflammation in bladder carcinoma is associated with angiogenesis and indicates good prognosis

Offersen, B. V., Knap, M., Marcussen, N., Horsman, M. R., Hamilton-Dutoit, S. J. & Overgaard, J., 2 dec. 2002, I: British Journal of Cancer. 87, 12, s. 1422-1430 9 s.

Comparison of methods of microvascular staining and quantification in prostate carcinoma: Relevance to Prognosis

Offersen, B. V., Borre, M., Sørensen, F. B. & Overgaard, J., feb. 2002, I: Acta Pathologica Microbiologica et Immunologica Scandinavica. 110, 2, s. 177-185 9 s.

Chalkley estimates of angiogenesis in early breast cancer--relevance to prognosis

Offersen, B. V., Sørensen, F. B., Yilmaz, M., Knoop, A., Overgaard, J. & Committee, D. B. C. C. G. T. B., 2002, I: Acta Oncologica. 41, 7-8, s. 695-703 9 s.

Comparison of methods of microvascular staining and quantification in prostate carcinoma: Relevance to prognosis

Offersen, B. V., Borre, M., Sørensen, FB. & Overgaard, J., 2002, I: Acta Pathologica Microbiologica et Immunologica Scandinavica. 110, s. 177-85

Comparison of methods of microvascular staining and quantification in prostate carcinoma: relevance to prognosis

Offersen, B. V., Borre, M., Sørensen, F. B. & Overgaard, J., 2002, I: Acta Pathologica Microbiologica et Immunologica Scandinavica. 110, 2, s. 177-85 8 s.

Patterns of angiogenesis in nonsmall-cell lung carcinoma

Offersen, B. V., Pfeiffer, P., Hamilton-Dutoit, S. & Overgaard, J., 15 apr. 2001, I: Cancer. 91, 8, s. 1500-1509 10 s.

Patterns of angiogenesis in nonsmall-cell lung carcinoma

Offersen, B. V., Pfeiffer, P., Hamilton-Dutoit, S. & Overgaard, J., 2001, I: Cancer. 91, 8, s. 1500-9 9 s.

Angiogenesis - a prognostic marker for prostate cancer

Borre, M., Offersen, B. V., Nerstrøm, B. & Overgaard, J., 1999, I: Ugeskrift for Laeger. 25, s. 3832-36

Immunohistochemical determination of tumour angiogenesis measured in the maximal microvessel density in human prostate cancer

Offersen, B. V., Borre, M. & Overgaard, J., 1998, I: Acta Pathologica Microbiologica et Immunologica Scandinavica. 106, s. 463-9

Mcrovessel density predicts survival in prostate cancer patients subjected to watchful waiting

Borre, M., Offersen, B. V., Nerstrøm, B. & Overgaard, J., 1998, I: British Journal of Cancer. 78, s. 940-4