Aarhus Universitet

Bente Vilsen

  1. 2019
  2. Udgivet

    Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation. / Mikkelsen, Stine A; Mogensen, Louise S; Vilsen, Bente; Molday, Robert S; Vestergaard, Anna L; Andersen, Jens Peter.

    I: Journal of Biological Chemistry, Bind 294, Nr. 15, 04.2019, s. 5970-5979.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  3. Udgivet

    Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase. / Roenn, Christian P; Li, Melody; Schack, Vivien R; Forster, Ian C; Holm, Rikke; Toustrup-Jensen, Mads S; Andersen, Jens P; Petrou, Steven; Vilsen, Bente.

    I: Journal of Biological Chemistry, Bind 294, Nr. 1, 04.01.2019, s. 269-280.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  4. Udgivet

    Distinct effects of Q925 mutation on intracellular and extracellular Na+ and K+ binding to the Na+, K+-ATPase. / Nielsen, Hang N; Spontarelli, Kerri; Holm, Rikke; Andersen, Jens Peter; Einholm, Anja P.; Artigas, Pablo; Vilsen, Bente.

    I: Scientific Reports, Bind 9, Nr. 1, 13344, 2019.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  5. 2018
  6. Udgivet

    Germline De Novo Mutations in ATP1A1 Cause Renal Hypomagnesemia, Refractory Seizures, and Intellectual Disability. / Schlingmann, Karl P; Bandulik, S; Mammen, C; Tarailo-Graovac, M; Jensen, Rikke Holm; Baumann, M; König, J; Lee, JJY; Drögemøller, B; Imminger, K; Beck, BB; Altmüller, J; Thiele, H; Waldegger, S; Van't Hoff, W; Kleta, R; Warth, R; van Karnebeek, CDM; Vilsen, Bente; Bockenhauer, Detlef; Konrad, M.

    I: American Journal of Human Genetics, Bind 103, Nr. 5, 01.11.2018, s. 808-816.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  7. 2017
  8. Udgivet

    Arginine replacement of Cys932 converts Na,K-ATPase to an electroneutral pump. Poster presented by Rikke Holm at the 15th International Conference on Na,K-ATPase and related Transport ATPases, Otsu, Japan, 2017. / Jensen, Rikke Holm; Khandelwal, Jaanki; Einholm, Anja P.; Andersen, Jens Peter; Artigas, Pablo; Vilsen, Bente.

    2017. Poster session præsenteret ved The 15th International Conference on Na,K-ATPase and related transport ATPases, Japan.

    Publikation: KonferencebidragPosterForskning

  9. Udgivet

    Astrocytic Na,K-ATPase a2b1 and a2b2 manages [K+]o differently during synaptic activity. Poster at the 15th International Conference on Na,K-ATPase and Related Transport ATPases, Otsu, Japan, 2017. / Larsen, Brian Roland; Stoica, Anca; Assentoft, Mette; Jensen, Rikke Holm; Holt, Leanne M.; Lykke-Hartmann, Karin; Olsen, Michelle L.; Vilsen, Bente; MacAulay, Nanna.

    2017.

    Publikation: KonferencebidragPosterForskning

  10. Udgivet
  11. Udgivet
  12. Udgivet
  13. Udgivet

    Disease mutations reveal residues critical to the interaction of P4-ATPases with lipid substrates. / Gantzel, Rasmus H; Mogensen, Louise S; Mikkelsen, Stine A; Vilsen, Bente; Molday, Robert S; Vestergaard, Anna L; Andersen, Jens P.

    I: Scientific Reports, Bind 7, Nr. 1, doi: 10.1038/s41598-017-10741-z., 05.09.2017, s. 10418.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  14. Udgivet

    Arginine substitution of a cysteine in transmembrane helix M8 converts Na+,K+-ATPase to an electroneutral pump similar to H+,K+-ATPase. / Holm, Rikke ; Khandelwal, J; Einholm, Anja P.; Andersen, Jens Peter; Artigas, Pablo; Vilsen, Bente.

    I: Proceedings of the National Academy of Sciences of the United States of America, Bind 114, Nr. 2, 10.01.2017, s. 316-321.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  15. Udgivet

    The α2β2 isoform combination dominates the astrocytic Na+ /K+ -ATPase activity and is rendered nonfunctional by the α2.G301R familial hemiplegic migraine type 2-associated mutation. / Stoica, Anca; Larsen, Brian; Assentoft, Mette; Jensen, Rikke Holm; Holt, Leanne; Vilhardt, Frederik; Vilsen, Bente; Lykke-Hartmann, Karin; MacAulay, Nanna.

    I: Glia, Bind 65, Nr. 11, 2017, s. 1777-1793.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  16. 2016
  17. Udgivet

    Glutamate transporter activity promotes enhanced Na+/K+-ATPase -mediated extracellular K+ management during neuronal activity. / Larsen, Brian R; Holm, Rikke; Vilsen, Bente; Macaulay, Nanna.

    I: The Journal of Physiology, Bind 594, Nr. 22, 15.11.2016, s. 6627-6641.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  18. Udgivet

    Neurological disease mutations of α3 Na+,K+-ATPase: Structural and functional perspectives and rescue of compromised function. / Holm, Rikke ; Toustrup-Jensen, Mads Schak; Einholm, Anja P.; Schack, Vivien; Andersen, Jens Peter; Vilsen, Bente.

    I: B B A - Bioenergetics, Bind 1857, Nr. 11, 11.2016, s. 1807–1828.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisReviewForskningpeer review

  19. Udgivet

    Importance of a potential protein kinase A phosphorylation site of Na+,K+-ATPase and its interaction network for Na+ binding. / Einholm, Anja P.; Nielsen, Hang Nguyen; Holm, Rikke; Toustrup-Jensen, Mads Schak; Vilsen, Bente.

    I: Journal of Biological Chemistry, Bind 291, Nr. 20, 13.05.2016, s. 10934-47.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  20. Udgivet
  21. 2015
  22. Udgivet

    Specific mutations in mammalian P4-ATPase ATP8A2 catalytic subunit entail differential glycosylation of the accessory CDC50A subunit. / Vestergaard, Anna L; Mikkelsen, Stine A; Coleman, Jonathan A; Molday, Robert S; Vilsen, Bente; Andersen, Jens Peter.

    I: FEBS Letters, Bind 589, 22.11.2015, s. 3908-3914.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  23. Udgivet

    Analysis of amino acid residues of potential importance for phosphatidylserine specificity of P4-type ATPase ARP8A2. / Mogensen, Louise; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; Coleman, Jonathan Allan; Vilsen, Bente; Molday, Robert S.; Andersen, Jens Peter.

    2015. Poster session præsenteret ved 4th International Workshop on Expression, Structure and Function of Membrane Proteins, Firenze, Italien.

    Publikation: KonferencebidragPosterForskning

  24. Udgivet
  25. Udgivet
  26. Udgivet

    Scanning mutagenesis of transmembrane segments M5 and M6 of the mammalian flippase ATP8A2 – evidence for a classic transport pathway? / Mikkelsen, Stine; Vestergaard, Anna Lindeløv; Coleman, Jonathan Allan; Vilsen, Bente; S. Molday, Robert; Andersen, Jens Peter.

    2015.

    Publikation: KonferencebidragPosterForskning

  27. Udgivet

    Rescue of Na+ affinity in aspartate 928 mutants of Na+,K+-ATPase by secondary mutation of glutamate 314. / Holm, Rikke; Einholm, Anja P; Andersen, Jens P; Vilsen, Bente.

    I: Journal of Biological Chemistry, Bind 290, Nr. 15, 10.04.2015, s. 9801-11.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  28. 2014
  29. Udgivet

    Functional study of selected ATP1A3 mutations causing alternating hemiplegia of childhood. / Rønn, Christian Philip; Schack, Vivien; Vilsen, Bente.

    2014.

    Publikation: KonferencebidragPosterForskning

  30. Udgivet

    Generation of transgenic Yucatan minipigs expressing the Na+,K+-ATPase, ATP1A3, disease mutations. / Henriksen, Carina; Liu, Ying; Madsen, Lone Bruhn; Schmidt, Mette; Bendixen, Christian; Thomsen, Bo; Callesen, Henrik; Larsen, Knud Erik; Vilsen, Bente.

    2014. Poster session præsenteret ved 14th International ATPase Conference “Na,K‐ATPase and related transport , Lunteren, Holland.

    Publikation: KonferencebidragPosterForskning

  31. Udgivet

    Generation of transgenic Yucatan minipigs expressing the Na+,K+-ATPase, ATP1A3, disease mutations. / Henriksen, Carina; Liu, Ying; Madsen, Lone Bruhn; Schmidt, Mette; Bendixen, Christian; Thomsen, Bo; Callesen, Henrik; Larsen, Knud Erik; Vilsen, Bente.

    2014. Abstract fra 14th International ATPase Conference “Na,K‐ATPase and related transport , Lunteren, Holland.

    Publikation: KonferencebidragKonferenceabstrakt til konferenceForskning

  32. Udgivet

    Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease. / Toustrup-Jensen, Mads Schak; Einholm, Anja P.; Schack, Vivien; Nielsen, Hang Nguyen; Holm, Rikke; Sobrido, Maria-Jesus; Andersen, Jens Peter; Clausen, Torben; Vilsen, Bente.

    2014. Poster session præsenteret ved 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Holland.

    Publikation: KonferencebidragPosterForskning

  33. Udgivet

    Rescue of Na+ and H+ binding in Na+,K+-ATPase M8 aspartate mutants by secondary mutation. / Holm, Rikke; Einholm, Anja P.; Andersen, Jens Peter; Vilsen, Bente.

    2014. Poster session præsenteret ved 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Holland.

    Publikation: KonferencebidragPosterForskning

  34. Udgivet

    Analysis of Amino Acid Residues of Potential Importance for Phosphati-dylserine Specificity of P4-type ATPase ATP8A2. / Mogensen, Louise; Vestergaard, Anna Lindeløv; Mikkelsen, Stine; Coleman, Jonathan Allan; Vilsen, Bente; Molday, Robert S.; Andersen, Jens Peter.

    2014. Poster session præsenteret ved 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Holland.

    Publikation: KonferencebidragPosterForskning

  35. Udgivet

    Darier disease mutation E917K of SERCA2b relieves the inhibitory influence of the 11th transmembrane segment. / Mikkelsen, Stine; Holdensen, Anne Nyholm; Vangheluwe, Peter; Vilsen, Bente; Andersen, Jens Peter.

    2014. Poster session præsenteret ved 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Holland.

    Publikation: KonferencebidragPosterForskning

  36. Udgivet

    Stability cluster links hydrofobic gate to K873 in ATP8A2. / Mikkelsen, Stine; Vestergaard, Anna Lindeløv; Coleman, Jonathan Allan; Vilsen, Bente; Molday, Robert S.; Andersen, Jens Peter.

    2014. Poster session præsenteret ved 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Holland.

    Publikation: KonferencebidragPosterForskning

  37. Udgivet

    GIutamate-induced astrocytic [Na+]i elevation – a mechanism to increase K+ clearance via the Na+/K+-ATPase? / Larsen, Brian R; Holm, Rikke; Vilsen, Bente; Macaulay, Nanna.

    2014. Poster session præsenteret ved 46th Sandbjerg Meeting on Membrane Transport, Danmark.

    Publikation: KonferencebidragPosterForskning

  38. Udgivet

    Distinct neurological disorders with ATP1A3 mutations. / Heinzen, Erin L; Arzimanoglou, Alexis; Brashear, Allison; Clapcote, Steven J; Gurrieri, Fiorella; Goldstein, David B; Jóhannesson, Sigurður H; Mikati, Mohamad A; Neville, Brian; Nicole, Sophie; Ozelius, Laurie J; Poulsen, Hanne; Schyns, Tsveta; Sweadner, Kathleen J; van den Maagdenberg, Arn; Vilsen, Bente; for the ATP1A3 Working Group: .

    I: Lancet Neurology, Bind 13, Nr. 5, 05.2014, s. 503-514.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  39. Udgivet

    Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2. / Vestergaard, Anna L; Coleman, Jonathan A; Lemmin, Thomas; Mikkelsen, Stine A; Molday, Laurie L; Vilsen, Bente; Molday, Robert S; Dal Peraro, Matteo; Andersen, Jens Peter.

    I: Proceedings of the National Academy of Sciences of the United States of America, Bind 111, Nr. 14, 08.04.2014, s. E1334-43.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  40. Udgivet

    Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease. / Toustrup-Jensen, Mads Schak; Einholm, Anja P.; Schack, Vivien; Nielsen, Hang Nguyen; Holm, Rikke; Sobrido, María-Jesús; Andersen, Jens Peter; Clausen, Torben; Vilsen, Bente.

    I: Journal of Biological Chemistry, Bind 289(6), 07.02.2014, s. 3186-3197.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  41. Udgivet

    Consequences of mutation to Gln923 for Na+ and K+ binding in Na+/K+-ATPase. / Nielsen, Hang Nguyen; Einholm, Anja P.; Vilsen, Bente.

    2014. Poster session præsenteret ved 14th International Conference Na,K-ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease, Lunteren, Holland.

    Publikation: KonferencebidragPosterForskning

  42. Udgivet

    Elucidation of the functional role of a potential PKA site in Na+,K+-ATPase: Importance of Ser938 in binding of intracellular Na+. / Einholm, Anja P.; Nielsen, Hang Nguyen; Holm, Rikke; Toustrup-Jensen, Mads Schak; Vilsen, Bente.

    2014. Poster session præsenteret ved 14th International Conference Na,K-ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease, Lunteren, Holland.

    Publikation: KonferencebidragPosterForskning

  43. Udgivet

    Importance of Residues Outside the Cation Binding Pocket for Na+ and K+ Binding to the Na+/K+-ATPase. / Christiansen, Line; Toustrup-Jensen, Mads Schak; Einholm, Anja P.; Vilsen, Bente.

    2014. Poster session præsenteret ved 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Holland.

    Publikation: KonferencebidragPosterForskning

  44. Udgivet

    Somatic ATP1A1, ATP2B3, and KCNJ5 Mutations in Aldosterone-Producing Adenomas. / Williams, Tracy Ann; Monticone, Silvia; Schack, Vivien R; Stindl, Julia; Burrello, Jacopo; Buffolo, Fabrizio; Annaratone, Laura; Castellano, Isabella; Beuschlein, Felix; Reincke, Martin; Lucatello, Barbara; Ronconi, Vanessa; Fallo, Francesco; Bernini, Giampaolo; Maccario, Mauro; Giacchetti, Gilberta; Veglio, Franco; Warth, Richard; Vilsen, Bente; Mulatero, Paolo.

    I: Hypertension, Bind 63(1), 2014, s. 188-195.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  45. Udgivet

    Somatic mutations in Na+,K+-ATPase and plasma membrane Ca2+-ATPase lead to aldosterone producing adenomas (Conn’s syndrome) : Presenting author: Vivien Schack. / Beuschlein, Felix; Boulkroun, Sheerazed; Osswald, Andrea; Wieland, Thomas; Nielsen, Hang Nguyen; Lichtenauer, Urs D; Penton, David; Schack, Vivien R.; Amar, Laurence; Fisher, Evelyn; Walther, Anett; Tauber, Philipp; Schwarzmayr, Thomas; Diener, Susanne; Graf, Elisabeth; Allolio, Bruno; Samson-Couterie, Benoit; Benecke, Arndt; Quinkler, Marcus; Fallo, Francesco; Plouin, Pierre-Francois; Mantero, Franco; Meitinger, Thomas; Mulatero, Paolo; Jeunemaitre, Xavier; Warth, Richard; Vilsen, Bente; Zennaro, Maria-Christina; Strom, Tim M; Reincke, Martin.

    2014. Poster session præsenteret ved 14th International ATPase Conference “Na,K‐ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease”, Lunteren, Holland.

    Publikation: KonferencebidragPosterForskning

  46. Udgivet
  47. 2013
  48. Udgivet

    Molecular Cloning and Characterization of Porcine Na+/K+-ATPase Isoforms α1, α2, α3 and the ATP1A3 Promoter. / Henriksen, Carina; Kjaer-Sorensen, Kasper; Einholm, Anja Pernille; Madsen, Lone Bruhn; Momeni, Jamal; Bendixen, Christian; Oxvig, Claus; Vilsen, Bente; Larsen, Knud .

    I: P L o S One, Bind 8, Nr. 11, e79127, 13.11.2013.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  49. Udgivet
  50. Udgivet
  51. Udgivet
  52. Udgivet

    Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state. / Kanai, Ryuta; Ogawa, Haruo; Vilsen, Bente; Cornelius, Flemming; Toyoshima, Chikashi.

    I: Nature, Bind 502, Nr. 7470, 10.10.2013, s. 201-6.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  53. Udgivet

    Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension. / Beuschlein, Felix; Boulkroun, Sheerazed; Osswald, Andrea; Wieland, Thomas; Nielsen, Hang N; Lichtenauer, Urs D; Penton, David; Schack, Vivien R; Amar, Laurence; Fischer, Evelyn; Walther, Anett; Tauber, Philipp; Schwarzmayr, Thomas; Diener, Susanne; Graf, Elisabeth; Allolio, Bruno; Samson-Couterie, Benoit; Benecke, Arndt; Quinkler, Marcus; Fallo, Francesco; Plouin, Pierre-Francois; Mantero, Franco; Meitinger, Thomas; Mulatero, Paolo; Jeunemaitre, Xavier; Warth, Richard; Vilsen, Bente; Zennaro, Maria-Christina; Strom, Tim M; Reincke, Martin.

    I: Nature Genetics, Bind 45, Nr. 4, 17.02.2013, s. 440–444.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  54. 2012
  55. Udgivet

    Na+,K+-ATPase amino acids involved in transport of the 3rd sodium ion. / Holm, Rikke; Einholm, Anja P.; Toustrup-Jensen, Mads Schak; Andersen, Jens Peter; Vilsen, Bente.

    2012. Poster session præsenteret ved 3rd International Workshop on Expression, Structure and Function of Membrane Proteins, Florence, Italien.

    Publikation: KonferencebidragPosterForskning

  56. Udgivet

    Flip i cellemembranen. / Vestergaard, Anna Lindeløv; Vilsen, Bente; Andersen, Jens Peter.

    I: Aktuel Naturvidenskab, Bind 2012-2, 09.05.2012, s. 18-19.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelFormidling

  57. Udgivet

    Critical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P4-ATPase ATP8A2. / Coleman, Jonathan A; Vestergaard, Anna L; Molday, Robert S; Vilsen, Bente; Andersen, Jens Peter.

    I: Proceedings of the National Academy of Sciences of the United States of America, Bind 109, Nr. 5, 31.01.2012, s. 1449-54.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  58. Udgivet

    Functional impacts of the Darier Disease mutation E917K/E918K and addition of two different tails to SERCA. / Mikkelsen, Stine; Holdensen, Anne Nyholm; Vilsen, Bente; Andersen, Jens Peter.

    2012. Poster session præsenteret ved 3rd International Workshop on Expression, Structure and Function of Membrane Proteins , Florence, Italien.

    Publikation: KonferencebidragPosterForskning

  59. Udgivet

    Genetic suppression of agrin reduces mania-like behavior in Na+ , K+ -ATPase α3 mutant mice. / Kirshenbaum, G S; Clapcote, S J; Petersen, J; Vilsen, Bente; Ralph, M R; Roder, J C.

    I: Genes, Brain and Behavior, Bind 11, Nr. 4, 2012, s. 436-43.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  60. Udgivet

    Inhibition of Phosphorylation of Na+,K+-ATPase by Mutations Causing Familial Hemiplegic Migraine. / Schack, Vivien Rodacker; Holm, Rikke; Rønn, Christian Philip; Vilsen, Bente.

    2012. Poster session præsenteret ved 3rd International Workshop on Expression, Structure and Function of Membrane Proteins, Florence, Italien.

    Publikation: KonferencebidragPosterForskning

  61. Udgivet

    Inhibition of phosphorylation of Na+,K+-ATPase by mutations causing familial hemiplegic migraine. / Schack, Vivien Rodacker; Holm, Rikke; Vilsen, Bente.

    I: Journal of Biological Chemistry, Bind 287, Nr. 3, 2012, s. 2191-202.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  62. Udgivet
  63. Udgivet
  64. Udgivet
  65. 2011
  66. Udgivet

    Destabilization of the Rossmann fold of Na+,K+-ATPase by mutations causing Familial Hemiplegic Migraine. / Schack, Vivien Rodacker; Holm, Rikke; Vilsen, Bente.

    2011. Poster session præsenteret ved 13th International P-type ATPase meeting, Pacific Grove, USA.

    Publikation: KonferencebidragPosterForskning

  67. Udgivet

    Characterization of the P4-ATPase ATP8A2: Critical Roles of Key Residues in the Fourth Transmembrane Segment in Aminophospholipid Transport : Poster for the 13th international ATPase conference, Pacific Grove, CA, USA. / Vestergaard, Anna Lindeløv; Coleman, Jonathan A.; Molday, Robert S.; Vilsen, Bente; Andersen, Jens Peter.

    2011. Poster session præsenteret ved 13th International ATPase conference, .

    Publikation: KonferencebidragPosterForskning

  68. Udgivet
  69. Udgivet

    Characterization of the P4-ATPase ATP8A2: Identification of Key Residues Involved in Catalysis and Lipid Transport : Poster for the 13th international ATPase conference, Pacific Grove, CA, USA. / Coleman, Jonathan Allan; Vestergaard, Anna Lindeløv; Molday, Robert S.; Vilsen, Bente; Andersen, Jens Peter.

    2011. Poster session præsenteret ved 13th international ATPase conference Na,K-ATPase and related ATPases, Asilomar, Pacific Grove, CA, USA.

    Publikation: KonferencebidragPosterForskning

  70. Udgivet

    A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps. / Morth, Jens Preben; Pedersen, Bjørn Panella; Buch-Pedersen, Morten Jeppe; Andersen, Jens Peter; Vilsen, Bente; Palmgren, Michael G; Nissen, Poul.

    I: Nature Reviews. Molecular Cell Biology, Bind 12, 01.2011, s. 60-70.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  71. Udgivet

    Decreased neuronal Na+, K+ -ATPase activity in Atp1a3 heterozygous mice increases susceptibility to depression-like endophenotypes by chronic variable stress. / Kirshenbaum, G S; Saltzman, K; Rose, B; Petersen, J; Vilsen, Bente; Roder, J C.

    I: Genes, Brain and Behavior, Bind 10, Nr. 5, 2011, s. 542-550.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  72. Udgivet

    Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase α3 sodium pump. / Kirshenbaum, Greer S; Clapcote, Steven J; Duffy, Steven; Burgess, Christian R; Petersen, Janne; Jarowek, Karolina J; Yücel, Yeni H; Cortez, Miguel A; Snead, O Carter; Vilsen, Bente; Peever, John H; Ralph, Martin R; Roder, John C.

    I: Proceedings of the National Academy of Sciences of the United States of America, Bind 108, Nr. 44, 2011, s. 18144-18149.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  73. Udgivet

    Na+,K+-ATPase amino acids involved in transport of the 3rd sodium ion. / Holm, Rikke; Einholm, Anja P.; Toustrup-Jensen, Mads Schak; Andersen, Jens Peter; Vilsen, Bente.

    2011. Poster session præsenteret ved 13th international ATPase conference Na,K-ATPase and related ATPases, Asilomar, Pacific Grove, CA, USA.

    Publikation: KonferencebidragPosterForskning

  74. Udgivet

    The rapid-onset dystonia parkinsonism mutation D923N of the Na+,K+-ATPase alpha3 isoform disrupts Na+ interaction at the third Na+ site and leads to a rise in intracellular Na+ in cell cultur. / Einholm, Anja P.; Toustrup-Jensen, Mads Schak; Holm, Rikke; Andersen, Jens Peter; Vilsen, Bente.

    2011. Poster session præsenteret ved 13th international ATPase conference Na,K-ATPase and related ATPases, Asilomar, Pacific Grove, CA, USA.

    Publikation: KonferencebidragPosterForskning

  75. Udgivet

    Two neurological disease mutations in the C-terminus of the Na+,K+-ATPase change the intracellular Na+ and K+ content in transfected mammalian COS-1 cell lines. / Toustrup-Jensen, Mads Schak; Einholm, Anja P.; Nielsen, Hang Nguyen; Holm, Rikke; Clausen, Torben; Vilsen, Bente.

    2011. Poster session præsenteret ved 13th international ATPase conference Na,K-ATPase and related ATPases, Asilomar, Pacific Grove, CA, USA.

    Publikation: KonferencebidragPosterForskning

  76. 2010
  77. Udgivet

    The rapid-onset dystonia Parkinsonism mutation D923N of the Na+,K+-ATPase alpha-3 isoform disrupts Na+interaction at the third Na+ site. / Einholm, Anja P.; Toustrup-Jensen, Mads Schak; Holm, Rikke; Andersen, Jens Peter; Vilsen, Bente.

    I: Journal of Biological Chemistry, Bind 285, Nr. 34, 20.08.2010, s. 26245-26254.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  78. Udgivet
  79. 2009
  80. Udgivet

    Mutation I810N in the A3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS. / Clapcote, Steven J.; Duffy, Steven; Xie, Gang; Kirshenbaum, Greer; Bechard, Allison R.; Schack, Vivien Rodacker; Petersen, Janne; Sinai, Laleh; Saab, Bechara J.; Lerch, Jason P.; Minassian, Berge A.; Ackerley, Cameron A.; Sled, John G.; Cortez, Miguel A.; Henderson, Jeffrey T.; Vilsen, Bente; Roder, John C.

    I: Proceedings of the National Academy of Sciences of the United States of America, Bind 106, Nr. 33, 18.08.2009, s. 14085-14090.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  81. Udgivet

    A C-terminal mutation of ATP1A3 underscores the crucial role of sodium affinity in the pathophysiology of rapid-onset dystonia-parkinsonism. / Blanco-Arias, Patricia; Einholm, Anja P.; Mamsa, Hafsa; Concheiro, Carla; Gutiérrez-de-Terán, Hugo; Romero, Jesús; Toustrup-Jensen, Mads Schak; Carracedo, Ángel; Jen, Joanna; Vilsen, Bente; Sobrido, María-Jesús.

    I: Human Molecular Genetics, Bind 18, Nr. 13, 2009, s. 2370-2377.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  82. Udgivet

    A new RDP mutation of ATP1A3 with an in-frame insertion of a tyrosine at the very C-terminus of the protein provides further evidence for a key regulatory role of the C-terminal tail of Na+,K+-ATPase. / Einholm, Anja P.; Toustrup-Jensen, Mads Schak; Holm, Rikke; Blanco-Arias, Patricia; Mamsa, Hafsa; Concheiro, Carla; Gutiérrez-Terán, Hugo; Romero, Jesús; Carracedo, Ángel; Jen, Joanna; Sorbrido, María-Jesús; Vilsen, Bente.

    2009. Poster session præsenteret ved 2nd International Workshop on Expression, Structure and Function of Membrane Proteins, Florence, Italien.

    Publikation: KonferencebidragPosterForskning

  83. Udgivet

    Crystal Structure of a type IIC P-type ATPase. / Morth, Jens Preben (Opfinder); Andersen, Jens Peter (Opfinder); Vilsen, Bente (Opfinder); Nissen, Poul (Opfinder).

    Patentnummer: PCT/DK2008/050307. dec. 12, 2008.

    Publikation: PatentForskning

  84. Udgivet

    Functional analysis of Na+,K+-ATPase mutations associated with two neurological disorders. / Schack, Vivien Rodacker; Holm, Rikke; Vilsen, Bente.

    2009. Poster session præsenteret ved 2nd International Workshop on Expression, Structure and Function of Membrane Proteins, Firenze, Italien.

    Publikation: KonferencebidragPosterForskning

  85. Udgivet

    Identification and Function of a Cytoplasmic K+ site of the Na+,K+-ATPase. / Schack, Vivien Rodacker; Vilsen, Bente.

    2009. Poster session præsenteret ved PhD Day 2009, Faculty of Health Sciences, University of Aarhus, Århus, Danmark.

    Publikation: KonferencebidragPosterForskning

  86. Udgivet

    P-type ATPases as drug targets: Tools for medicine and science. / Yatime, Laure; Buch-Pedersen, Morten Jeppe; Musgaard, Maria; Morth, Jens Preben; Winther, Anne-Marie Lund; Pedersen, Bjørn Panyella; Olesen, Claus Elsborg; Andersen, Jens Peter; Vilsen, Bente; Schiøtt, Hanne Birgit; Palmgren, Michael; Møller, Jesper Vuust; Nissen, Poul; Fedosova, Natalya.

    I: B B A - Bioenergetics, Bind 1787, Nr. 4, 2009, s. 207-20.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  87. Udgivet

    The C Terminus of Na+,K+-ATPase Controls Na+ Affinity on Both Sides of the Membrane through Arg935. / Toustrup-Jensen, Mads Schak; Holm, Rikke; Einholm, Anja P.; Schack, Vivien Rodacker; Morth, Jens Preben; Nissen, Poul; Andersen, Jens Peter; Vilsen, Bente.

    I: Journal of Biological Chemistry, Bind 284, Nr. 28, 2009, s. 18715-18725.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  88. Udgivet

    The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations. / Morth, J Preben; Poulsen, Hanne; Toustrup-Jensen, Mads S; Schack, Vivien Rodacker; Egebjerg, Jan; Andersen, Jens Peter; Vilsen, Bente; Nissen, Poul.

    I: Royal Society of London. Philosophical Transactions. Biological Sciences, Bind 364, Nr. 1514, 2009, s. 217-27.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  89. 2008
  90. Udgivet

    Crystal Structure of D351A and P312A Mutant Forms of the Mammalian Sarcoplasmic Reticulum Ca2+-ATPase Reveals Key Events in Phosphorylation and Ca2+ Release. / Marchand, Alexandre; Winther, Anne-Marie Lund; Holm, Peter; Olesen, Claus; Montigny, Cedric; Arnou, Bertrand; Champeil, Philippe; Clausen, Johannes D.; Vilsen, Bente; Andersen, Jens Peter; Nissen, Poul; Jaxel, Christine; Møller, Jesper Vuust; le Maire, Marc.

    I: Journal of Biological Chemistry, Bind 283, Nr. 21, 2008, s. 14867-14882.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  91. Udgivet

    Electrophysiological studies of a proposed voltage modulator in the Na,K-ATPase. / Poulsen, Hanne; Morth, Jens Preben; Vilsen, Bente; Jensen, Jan Egebjerg; Nissen, Poul.

    2008. Poster session præsenteret ved 12th International ATPase Conference: Na,K-ATPase and Related Transport ATPases of P-type: Structures, Mechanisms, and Roles in Health and Disease, Aarhus, Danmark.

    Publikation: KonferencebidragPosterForskning

  92. Udgivet

    Functional analysis of a potential regulatory K+-binding site in the Na+, K+-ATPase. / Schack, Vivien Rodacker; Vilsen, Bente.

    2008. Poster session præsenteret ved PhD day 2008, Faculty of Health Sciences, University of Aarhus, Århus, Danmark.

    Publikation: KonferencebidragPosterForskning

  93. Udgivet

    Identification and function of a cytoplasmic K+ site of the Na+,K+-ATPase. / Schack, Vivien Rodacker; Morth, Jens Preben; Toustrup-Jensen, Mads Schak; Anthonisen, Anne Nyholm; Nissen, Poul; Andersen, Jens Peter; Vilsen, Bente.

    2008. Poster session præsenteret ved 12th International ATPase Conference:  Na,K-ATPase and Related Transport ATPases of P-type: Structures, Mechanisms, and Roles in Health and Disease, Aarhus, Danmark.

    Publikation: KonferencebidragPosterForskning

  94. Udgivet

    Identification and function of a cytoplasmic K+ site of the Na+,K+ATPase. / Schack, Vivien Rodacker; Morth, Jens Preben; Toustrup-Jensen, Mads S; Anthonisen, Anne Nyholm; Nissen, Poul; Andersen, Jens Peter; Vilsen, Bente.

    I: Journal of Biological Chemistry, Bind 283, Nr. 41, 2008, s. 27982-90.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  95. Udgivet

    Importance of Ser938 for Na+ binding to Na+,K+-ATPase. / Einholm, Anja P.; Jensen, Rikke Holm; Toustrup-Jensen, Mads Schak; Andersen, Jens Peter; Vilsen, Bente.

    2008. Poster session præsenteret ved 12th International ATPase Conference: Na,K-ATPase and Related Transport ATPases of P-type: Structures, Mechanisms, and Roles in Health and Disease., Aarhus, Danmark.

    Publikation: KonferencebidragPosterForskning

  96. Udgivet

    Na+,K+ pumpen vedbliver at overraske. / Vilsen, Bente.

    I: Ugeskrift for Laeger, Bind 170, Nr. 21, 2008, s. 1821-1823.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisReviewForskning

  97. 2007
  98. Udgivet

    ATP-binding Modes and Functionally Important Interdomain Bonds of Sarcoplasmic Reticulum Ca2+-ATPase Revealed by Mutation of Glycine 438, Glutamate 439, and Arginine 678. / Clausen, Johannes D.; McIntosh, David B.; Anthonisen, Anne Nyholm; Woolley, David G.; Vilsen, Bente; Andersen, Jens Peter.

    I: Journal of Biological Chemistry, Bind 282, Nr. 28, 2007, s. 20686-20697.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  99. Udgivet

    Crystal structure of the sodium-potassium pump. / Morth, J Preben; Pedersen, Bjørn Panyella; Toustrup-Jensen, Mads S; Sørensen, Thomas L-M; Petersen, Janne; Andersen, Jens Peter; Vilsen, Bente; Nissen, Poul.

    I: Nature, Bind 450, Nr. 7172, 2007, s. 1043-1049.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  100. Udgivet

    Importance of Leu99 in transmembrane segment M1 of the Na+, K+ -ATPase in the binding and occlusion of K+. / Einholm, Anja P.; Andersen, Jens Peter; Vilsen, Bente.

    I: Journal of Biological Chemistry, Bind 282, Nr. 33, 2007, s. 23854-23866.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  101. Udgivet

    Mutations Phe785Leu and Thr618Met in Na+, K+-ATPase, Associated with Familial Rapid-Onset Dystonia Parkinsonism, Interfere with Na+ Interaction by Distinct Mechanisms. / Schack, Vivien Rodacker; Toustrup-Jensen, Mads Schak; Vilsen, Bente.

    2007. Poster session præsenteret ved PhD day 2007, Faculty of Health Sciences, University of Aarhus, Århus, Danmark.

    Publikation: KonferencebidragPosterForskning

  102. Udgivet

    Mutations Phe785Leu and Thr618Met in Na+, K+-ATPase, Associated with Familial Rapid-Onset Dystonia Parkinsonism, Interfere with Na+ Interaction by Distinct Mechanisms. / Schack, Vivien Rodacker; Toustrup-Jensen, Mads Schak; Vilsen, Bente.

    2007. Poster session præsenteret ved Membrane Protein Isolation, Crystallization and Structure Determination (TRAMP-6), Århus, Danmark.

    Publikation: KonferencebidragPosterForskning

  103. Udgivet

    Roles of transmembrane segment M1 of Na(+),K (+)-ATPase and Ca (2+)-ATPase, the gatekeeper and the pivot. / Einholm, Anja P.; Andersen, Jens Peter; Vilsen, Bente.

    I: Journal of Bioenergetics and Biomembranes, Bind 39, Nr. 5-6, 2007, s. 357-366.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisReviewForskning

  104. 2006
  105. Udgivet

    Asparagine 706 and glutamate 183 at the catalytic site of sarcoplasmic reticulum Ca2+-ATPase play critical but distinct roles in E2 states. / Clausen, Johannes D.; McIntosh, David B.; Woolley, David G.; Anthonisen, Anne Nyholm; Vilsen, Bente; Andersen, Jens Peter.

    I: Journal of Biological Chemistry, Bind 281, 2006, s. 9471-9481.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  106. Udgivet

    Mutations Phe785Leu and Thr618Met in Na+,K+-ATPase, associated with Familial Rapid-onset Dystonia Parkinsonism, interfere with Na+ interaction by distinct mechanisms. / Rodacker, Vivien; Jensen, Mads Toustrup; Vilsen, Bente.

    I: Journal of Biological Chemistry, Bind 281, Nr. 27, 2006, s. 18539-18548.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  107. 2005
  108. Udgivet

    Functional Comparison between Secretory Pathway Ca2+/Mn2+-ATPase (SPCA) 1 and Sarcoplasmic Reticulum Ca2+-ATPase (SERCA) 1 Isoforms by Steady-state and Transient Kinetic Analyses. / Dode, L.; Andersen, Jens Peter; Raeymaekers, L.; Missiaen, L.; Vilsen, Bente; Wuytack, F.

    I: Journal of Biological Chemistry, Bind 280, 2005, s. 39124-39134.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  109. Udgivet

    Interaction between the Catalytic Site and the A-M3 Linker Stabilizes E2/E2P Conformational States of Na+,K+-ATPase. / Jensen, Mads Toustrup; Vilsen, Bente.

    I: Journal of Biological Chemistry, Bind 280, 2005, s. 10210-10218.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  110. Udgivet

    Mutation Phe785-Leu, Associated with Rapid-onset Dystonia Parkinsonism, in the Na+, K+-ATPase, Interferes Severely with the Na+Binding Properties but not with the K+ Binding Properties. / Schack, Vivien Rodacker; Toustrup-Jensen, Mads Schak; Vilsen, Bente.

    2005. Poster session præsenteret ved 11th International Conference on the Na+/K+-ATPase and Related ATPases, Woods Hole, USA.

    Publikation: KonferencebidragPosterForskning

  111. Udgivet

    Mutation of Gly-94 in transmembrane segment M1 of Na+, K+-ATPase interferes with Na+ and K+ binding in E2P conformation. / Einholm, Anja P.; Jensen, Mads Toustrup; Andersen, Jens Peter; Vilsen, Bente.

    I: Proceedings of the National Academy of Science, USA, Bind 102, 2005, s. 11254-11259.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  112. 2004
  113. Udgivet

    Glutamate-183 in the conserved TGES motif of domain A of sarcoplasmic reticulum Ca2+-ATPase assists in catalysis of E2/E2P partial reactions. / Clausen, J.D.; Vilsen, B.; McIntosh, D.B.; Einholm, A.P.; Andersen, J.P.

    I: Proceedings of the National Academy of Sciences of the United States of America, Bind 101, 2004, s. 2776-2781.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  114. Udgivet

    Importance of transmembrane segment M1 of the sarcoplasmic reticulum Ca2+-ATPase in Ca2+ occlusion and phosphoenzyme processing. / Einholm, A.P.; Vilsen, B.; Andersen, J.P.

    I: Journal of Biological Chemistry, Bind 279, 2004, s. 15888-15896.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  115. Udgivet

    Localization of a K+-binding Site Involved in Dephosphorylation of the Sarcoplasmic Reticulum Ca2+-ATPase. / Sørensen, Thomas Lykke-Møller; Clausen, Johannes D.; Jensen, A.-M., L.; Vilsen, Bente; Møller, J.V.; Andersen, Jens Peter; Nissen, Poul.

    I: Journal of Biological Chemistry, Bind 279, Nr. 45, 2004, s. 46355-46358.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  116. Udgivet

    Roles of conserved P-domain residues and Mg2+ in ATP binding in the ground and Ca2+-activated states of sarcoplasmic reticulum Ca2+-ATPase. / McIntosh, D.B.; Clausen, J.D.; Woolley, D.G.; MacLennan, D.H.; Vilsen, B.; Andersen, J.P.

    I: Journal of Biological Chemistry, Bind 279, 2004, s. 32515-32523.

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

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