Aarhus University Seal / Aarhus Universitets segl

Asbjørn Mohr Drewes

Risk of gastrointestinal cancer in patients with unexplained chest/epigastric pain and normal upper endoscopy: a Danish 10-year follow-up study

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelRådgivning

  • Kardiovaskulært Forskningscenter, Aalborg Sygehus
  • Kirurgisk Afdeling L, NBG
  • Klinisk Epidemiologi
  • Medicinsk Gastroenterologisk Afdeling, Medicinsk Center, Aalborg Sygehus
  • Kirurgisk Gastroenterologisk Afdeling Aalborg
  • Center for visceral biomekanik og smerte, AAL
Unexplained chest/epigastric pain is a common symptom in the general population. However, it has not previously been studied whether such pain could be a marker of subsequent gastrointestinal cancer. We aimed to estimate the risk of gastrointestinal cancers in a Danish 10-year follow-up study among patients with chest/epigastric pain, normal upper endoscopy, and no prior discharge diagnosis of ischemic heart disease (N = 386), compared with population controls (N = 3860). The overall 10-year risk of gastrointestinal cancer (stomach, colorectal, liver, and pancreas) was 2.9% for patients with unexplained chest/epigastric pain vs. 1.5% for controls. The adjusted relative risks <1 year and > or =1 year after upper endoscopy were 8.4 (95% confidence interval [CI], 2.6-27.5) and 1.2 (95% CI, 0.5-2.9), respectively. We found that patients with unexplained chest/epigastric pain have an increased risk of gastrointestinal cancer within the first year after upper endoscopy. Consequently, unexplained chest/epigastric pain might be an early gastrointestinal cancer symptom.
OriginalsprogEngelsk
TidsskriftDigestive Diseases and Sciences
Vol/bind52
Nummer7
Sider (fra-til)1730-7
Antal sider7
ISSN0163-2116
DOI
StatusUdgivet - 2007

Se relationer på Aarhus Universitet Citationsformater

ID: 10183832