Asbjørn Mohr Drewes

Ravages of Diabetes on Gastrointestinal Sensory-Motor Function: Implications for Pathophysiology and Treatment

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

DOI

  • Hans Gregersen, Giome Center, College of Bioengineering, Chongqing University, Chongqing, China
  • ,
  • Donghua Liao
  • ,
  • Anne Mohr Drewes
  • ,
  • Asbjørn Mohr Drewes
  • Jingbo Zhao

Symptoms related to functional and sensory abnormalities are frequently encountered in patients with diabetes mellitus. Most symptoms are associated with impaired gastric and intestinal function. In this review, we discuss basic concepts of sensory-motor dysfunction and how they relate to clinical findings and gastrointestinal abnormalities that are commonly seen in diabetes. In addition, we review techniques that are available for investigating the autonomic nervous system, neuroimaging and neurophysiology of sensory-motor function. Such technological advances, while not readily available in the clinical setting, may facilitate stratification and individualization of therapy in diabetic patients in the future. Unraveling the structural, mechanical, and sensory remodeling in diabetes disease is based on a multidisciplinary approach that can bridge the knowledge from a variety of scientific disciplines. The final goal is to increase the understanding of the damage to GI structures and to sensory processing of symptoms, in order to assist clinicians with developing an optimal mechanics based treatment.

OriginalsprogEngelsk
Artikelnummer6
TidsskriftCurrent Gastroenterology Reports
Vol/bind18
Nummer2
Antal sider10
ISSN1534-312X
DOI
StatusUdgivet - jan. 2016

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